Conference Program Home
My Program
All Times EDT
Legend:
CC = Walter E. Washington Convention Center M = Marriott Marquis Washington, DC
* = applied session ! = JSM meeting theme
Activity Details
5 *
Sun, 8/7/2022,
2:00 PM -
3:50 PM
CC-201
Innovations in Digital Pathology and Spatial Transcriptomics: Statistical Challenges and Major Impacts — Invited Papers
International Chinese Statistical Association , Biometrics Section, Section on Statistics in Genomics and Genetics
Organizer(s): Himel Mallick, Merck Research Laboratories
Chair(s): Richard Baumgartner, Merck Research Laboratories
2:05 PM
Multi-Scale and Multi-Sample Analysis Enables Accurate Cell Type Clustering and Spatial Domain Detection in Spatial Transcriptomics
Zheng Li, University of Michigan ; Xiang Zhou, University of Michigan
2:25 PM
IHC Guided Deep Learning Myeloid Cell Detection Model Using HandE Data
Jeong Hwan Kook, Merck Research Laboratories
2:45 PM
Bayesian Modeling of Spatial Molecular Profiling Data
Qiwei Li, The University of Texas at Dallas ; Xi Jiang, Southern Methodist University; Minzhe Zhang, The University of Texas Southwestern Medical Center; Guanghua Xiao, The University of Texas Southwestern Medical Center
3:05 PM
A User-Friendly Tool for Cloud-Based, Whole-Slide Image Segmentation with Applications to Renal Histopathology
Pinaki Sarder, University at Buffalo
3:25 PM
Biomarker Discovery in Spatial Transcriptomics and Digital Pathology
Himel Mallick, Merck Research Laboratories
3:45 PM
Floor Discussion
22 * !
Sun, 8/7/2022,
2:00 PM -
3:50 PM
CC-143B
Statistical Learning in Cancer Medicine: From Early-Phase Trials to Preclinical Systems — Topic Contributed Papers
International Chinese Statistical Association , Biometrics Section, Section on Statistical Learning and Data Science
Organizer(s): Li-Xuan Qin, Memorial Sloan Kettering Cancer Center
Chair(s): Li-Xuan Qin, Memorial Sloan Kettering Cancer Center
2:05 PM
Hybrid Designs Using Concurrent Randomized Controls and Historical Evidence
Mithat Gonen, Memorial Sloan Kettering Cancer Center
2:25 PM
A Review of Bayesian Early-Phase Clinical Trials in Cancer Research
Hao Liu, Rutgers University
2:45 PM
Treatment Response Data for Patient-Derived Xenografts
Michael Lloyd, The Jackson Laboratory; Soner Koc, Seven Bridges Genomics; Anuj Srivastava, The Jackson Laboratory; Vivek Philip, The Jackson Laboratory; Tim Stearns, The Jackson Laboratory; Carol Bult, The Jackson Laboratory; Yvonne Evrard, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research; Jeffrey Moscow, Investigational Drug Branch, National Cancer Institute; Funda Meric-Bernstam, The University of Texas MD Anderson Cancer Center; Dennis Dean, Seven Bridges Genomics; Jeffrey H. Chuang, The Jackson Laboratory for Genomic Medicine
3:05 PM
Probabilistic Learning of Treatment Trees in Cancer
Veera Baladandayuthapani, University of Michigan ; Tsung-Hung Yao, University of Michigan; Zhenke Wu, University of Michigan, Ann Arbor; Karthik Bharath, University of Nottingham
3:25 PM
Discussant: Lisa McShane, National Cancer Institute
3:45 PM
Floor Discussion
38 !
Sun, 8/7/2022,
4:00 PM -
5:50 PM
CC-144B
Recent Advances in Adaptive Treatment Strategy Estimation — Invited Papers
Section on Statistics in Epidemiology , International Chinese Statistical Association, Section on Statistical Learning and Data Science
Organizer(s): Ai Ni, The Ohio State University
Chair(s): Yuan Chen, Memorial Sloan Kettering Cancer Center
4:05 PM
Adaptive Respondent-Driven Sampling
Eric Laber, Duke University ; Justin Weltz, Duke University; Alex Volfovsky, Duke University
4:30 PM
Ranking Tailoring Variables for Constructing Individualized Treatment Rules
Jiacheng Wu, University of Washington; Nina Galanter, University of Washington; Susan M Shortreed, Kaiser Permanente Washington Health Research Institute ; Erica EM Moodie, McGill University
4:55 PM
Contrast-Based Optimal Treatment Rule Estimation with Composite Survival Data
Ai Ni, The Ohio State University ; Xiaohan Guo, The Ohio State University
5:20 PM
Discussant: Yuanjia Wang, Columbia University
5:40 PM
Floor Discussion
82 * !
Mon, 8/8/2022,
8:30 AM -
10:20 AM
CC-152A
New Statistical Methods for Survival Analysis in Complex Biomedical Studies — Invited Papers
Lifetime Data Science Section , International Chinese Statistical Association, Biometrics Section
Organizer(s): Qingning Zhou, University of North Carolina at Charlotte
Chair(s): Qingning Zhou, University of North Carolina at Charlotte
8:35 AM
Support Vector Machine for Dynamic Survival Prediction with Time-Dependent Covariates
Wenyi Xie, University of North Carolina; Donglin Zeng, University of North Carolina ; Yuanjia Wang, Columbia University
9:00 AM
Some Recent Advances on Variable Selection for Interval-Censored Failure Time Data
(Tony) Jianguo J Sun, UNIVERSITY OF MISSOURI-COLUMBIA
9:25 AM
Spatial Dependence Modeling of Latent Susceptibility and Time to Joint Damage in Psoriatic Arthritis
Fangya Mao, University of Waterloo ; Richard Cook, University of Waterloo
9:50 AM
Feature Screening for Case-Cohort Studies with Failure Time Outcome
Jianwen Cai, University of North Carolina at Chapel Hill ; Jing Zhang, Zhongnan University of Economics and Law; Yanyan Liu, Wuhan University; Haibo Zhou, University of North Carolina at Chapel Hill
10:15 AM
Floor Discussion
100 * !
Mon, 8/8/2022,
8:30 AM -
10:20 AM
CC-150B
Cross Trial Borrowing in Drug Development: The Promising Potentials — Topic Contributed Papers
Biopharmaceutical Section , International Chinese Statistical Association, Section on Risk Analysis
Organizer(s): Qian Li, Statistics and Data Corporation
Chair(s): Qian Li, Statistics and Data Corporation
8:35 AM
Borrowing Information of a Surrogate Endpoint for Planning a Phase III Study
Hui Quan, Sanofi ; Zhixing Xu, Sanofi; Gautier Paux, Sanofi; Meehyung Cho, Sanofi; Xun Chen, Sanofi
8:55 AM
Implementation of Enrichment Designs in Platform Settings
Yeh-Fong Chen, Food and Drug Administration ; Feiran Jiao, FDA
9:15 AM
Type I Error Control Strategies Using a Conditional Hybrid Control in Randomized Clinical Trials
Hongyan Li, Statistics & Data Corporation ; Qian Li, Statistics and Data Corporation; Adam Hamm, Statistics & Data Corporation
9:35 AM
Discussant: Thomas Gwise, FDA/CDER
9:55 AM
Discussant: Qing Liu
10:15 AM
Floor Discussion
136 * !
Mon, 8/8/2022,
10:30 AM -
12:20 PM
CC-144C
Recent Advances in Clustered Time-to-Event Data — Topic Contributed Papers
Lifetime Data Science Section , International Chinese Statistical Association, Biometrics Section
Organizer(s): Mei-Ling Ting Lee, University of Maryland
Chair(s): (Tony) Jianguo J Sun, UNIVERSITY OF MISSOURI-COLUMBIA
10:35 AM
On the Analysis of Clustered Survival Data
DAVID OAKES, University of Rochester,
10:55 AM
Estimation and Testing for Clustered Bivariate Survival Databased on an Interval-Censored Version of the Clayton-Oakes Model
Bernard Rosner, Harvard Medical School ; Camden Bay, Harvard Medical School; Robert Glynn, Harvard Medical School; Gui-Shuang Ying, University of Pennsylvania; Maureen Maguire, University of Pennsylvania; Mei-Ling Ting Lee, University of Maryland
11:15 AM
Design and Analysis Methods for Randomized Clinical Trials with Clustered Survival Endpoints
Sin-Ho Jung, Duke University School of Medicine ; Jianghao Li, Eli Lilly and Company
11:35 AM
Adjusting for Informative Cluster Size in Pseudo-Value-Based Regression Approaches with Clustered Time-to-Event Data
Samuel C Anyaso-Samuel, University of Florida ; Somnath Datta, University of Florida
11:55 AM
Discussant: Jong H Jeong, University of Pittsburgh
12:15 PM
Floor Discussion
178
Mon, 8/8/2022,
2:00 PM -
3:50 PM
CC-101
Memorial Session for Michael Woodroofe — Invited Papers
Memorial , Caucus for Women in Statistics, IMS, International Chinese Statistical Association
Organizer(s): Bodhisattva Sen, Columbia University
Chair(s): Mary C Meyer, Colorado State University
2:05 PM
Michael Woodroofe: Statistician and Friend
David Siegmund, Stanford University
2:35 PM
Beautiful Ideas, Beautiful Mind, Impact Then, Now and Future - in Memory of Woodroofe
Jiayang Sun, George Mason University
3:05 PM
Michael Woodroofe: Shape Constraints and Biased Sampling Models
Jon Wellner, University of Washington
3:35 PM
Floor Discussion
217 * !
Tue, 8/9/2022,
8:30 AM -
10:20 AM
CC-150B
Theory and Algorithms for Adaptive Clinical Trial Design with Multiple Objectives — Invited Papers
WNAR , International Chinese Statistical Association, Biopharmaceutical Section
Organizer(s): Ying Lu, Stanford University School of Medicine
Chair(s): Ying Lu, Stanford University School of Medicine
8:35 AM
Grammar of Group Sequential Design
Presentation
Keaven M Anderson, Merck & Co., Inc. ; Yilong Zhang, Merck & Co., Inc.; Nan Xiao, Merck & Co., Inc.; Yujie Zhao, Merck & Co., Inc.
9:00 AM
Tight, Rigorous, and Automated Type I Error Proofs with Simulation
Michael Benjamin Sklar, Stanford University
9:25 AM
Optimizing Patient Enrollment in Global Clinical Trials by Metaheuristics
Weng Kee Wong, UCLA ; Mitchell Schepps, UCLA; Austin Matt, Amgen; Vlad Anisimov, Amgen
9:50 AM
Multi-Objective Approach to Assist in Selection of Efficient Clinical Trial Operation Design with Respect to Minimizing Expected Recruitment Time and the Geographic Site Footprint
Austin Matt, Amgen ; Vlad Anisimov, Amgen
10:15 AM
Floor Discussion
270 * !
Tue, 8/9/2022,
10:30 AM -
12:20 PM
CC-151B
Advanced Multivariate Time Series Modeling — Topic Contributed Papers
International Chinese Statistical Association , Business and Economic Statistics Section, Section on Statistical Learning and Data Science
Organizer(s): Mengyu Xu, University of Central Florida
Chair(s): Rui Xie, University of Central Florida
10:35 AM
A Stratified Penalization Method for Semiparametric Variable Labeling of Multi-Output, Time-Varying Coefficient Models
Ting Zhang, University of Georgia; Weiliang Wang, Boston University ; Yu Shao, Boston University
10:55 AM
CP Factor Model for Dynamic Tensors
Yuefeng Han, Rutgers University ; Rong Chen, Rutgers University; Cun-Hui Zhang, Rutgers University
11:15 AM
Tail Adversarial Stability for Linear Processes
Shuyang Bai, University of Georgia ; Ting Zhang, University of Georgia
11:35 AM
Recursive Quantile Estimation: Non-Asymptotic Confidence Bounds
Likai Chen, Washington University in Saint Louis ; Wei Biao Wu, University of Chicago; Georg Keilbar, University of Vienna
11:55 AM
Minimax Nonparametric Multiple-Sample Test Under Smoothing
Xin Xing, Virginia Tech
12:15 PM
Floor Discussion
310 * !
Tue, 8/9/2022,
2:00 PM -
3:50 PM
CC-152A
Data Integration and Information Synthesis in Survival Analysis — Invited Papers
Lifetime Data Science Section , Section on Statistics in Epidemiology, International Chinese Statistical Association
Organizer(s): Hong Zhu, University of Texas Southwestern Medical Center
Chair(s): Hong Zhu, University of Texas Southwestern Medical Center
2:05 PM
Risk Projection for Time-to-Event Outcome Leveraging Summary Statistics in the Target Population
Li Hsu, Fred Hutchinson Cancer Research Center ; Jiayin Zheng, Fred Hutchinson Cancer Research Center; Yingye Zheng, Fred Hutchinson Cancer Research Center
2:30 PM
Accommodating Population Differences in Model Validation
Ruth Pfeiffer, National Cancer Institute ; Yiyao Chen, Technical University of Munich; Mitchell Gail, National Cancer Institute; Donna P. Ankerst, Technical University of Munich
2:55 PM
Data Integration and Information Synthesis When Different Studies Have Similar but Not Exactly the Same Distribution
Jing Qin, Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases
3:20 PM
Cautionary Tales of 'Old' RCT Evidence in 'New' Era
Yu Shen, UT MD Anderson Cancer Center ; Jing Ning, UT MD Anderson Cancer Center
3:45 PM
Floor Discussion
364 * !
Wed, 8/10/2022,
8:30 AM -
10:20 AM
CC-151A
Modern Nonparametric Methods, with Applications in Complex Biomedical Data — Invited Papers
Section on Nonparametric Statistics , International Chinese Statistical Association, Section on Statistical Learning and Data Science
Organizer(s): Tracy Ke, Harvard University
Chair(s): Tracy Ke, Harvard University
8:35 AM
Distributed Nonparametric Function Estimation: Optimal Rate of Convergence and Cost of Adaptation
Tony Cai, University of Pennsylvania
9:00 AM
Fast, Model-Agnostic Confidence Intervals for Feature Importance
Genevera Allen, Rice University ; Lili Zheng, Rice University; Luqin Gan, Rice University
9:25 AM
Transfer Learning Under High-Dimensional Generalized Linear Models
Yang Feng, New York University ; Ye Tian, Columbia University
9:50 AM
Statistical Inference for Linear Mediation Models with High-Dimensional Mediators
Runze Li, Penn State University ; Xu Guo, Beijing Normal University; Jingyuan Liu, Xiamen University; Mudong Zeng, Penn State University
10:15 AM
Floor Discussion
374 * !
Wed, 8/10/2022,
8:30 AM -
10:20 AM
CC-201
Bayesian Clinical Trial Designs with Heterogeneous Patient Subgroups — Topic Contributed Papers
Biopharmaceutical Section , International Chinese Statistical Association, Section on Bayesian Statistical Science
Organizer(s): Kentaro Takeda, Astellas Pharma Global Development, Inc.
Chair(s): Kentaro Takeda, Astellas Pharma Global Development, Inc.
8:35 AM
Dose Finding with Heterogeneous Patient Subgroups
ANASTASIA IVANOVA, UNC at Chapel Hill ; Pooja Saha, Center for Biostatistics in AIDS Research, Department of Biostatistics, Harvard T.H. Chan
8:55 AM
Group-Sequential Enrichment Designs Based on Adaptive Regression of Response and Survival Time on High-Dimensional Covariates
Yeonhee Park, University of Wisconsin-Madison ; Suyu Liu, The University of Texas MD Anderson Cancer Center; Peter Thall, The University of Texas MD Anderson Cancer Center; Ying Yuan , the University of Texas MD Anderson Cancer Center
9:15 AM
BAGS: A Bayesian Adaptive Group Sequential Trial Design with Subgroup-Specific Survival Comparisons
Ruitao Lin, MD Anderson ; Peter Thall, The University of Texas MD Anderson Cancer Center; Ying Yuan , the University of Texas MD Anderson Cancer Center
9:35 AM
Bayesian Divide-and-Conquer Propensity Score–Based Approaches for Leveraging Real-World Data in Randomized Control Trials
Eric Baron, University of Connecticut ; Jian Zhu, Servier Pharmaceuticals; Sammi Tang, Servier Pharmaceuticals; Ming-Hui Chen, University of Connecticut
9:55 AM
Incorporating Historical Information for Randomized Clinical Trials: Dynamic Borrowing with Bias Control
Masataka Taguri, Yokohama City University
10:15 AM
Floor Discussion
385
Wed, 8/10/2022,
8:30 AM -
10:20 AM
CC-140A
SPEED: Statistical Methods and Applications in Medical Research, Risk Analysis, and Marketing Part 1 — Contributed Speed
Biopharmaceutical Section , Section on Medical Devices and Diagnostics, Section on Statistics in Imaging, IMS, International Chinese Statistical Association, Section on Risk Analysis, Section on Statistics in Marketing
Chair(s): Michael Higgins, Kansas State University
8:35 AM
Near Real-Time Surveillance of COVID-19 Vaccine Safety in the U.S. Food and Drug Administration Biologics Effectiveness and Safety (BEST) Initiative Data Network
Mao Hu, Acumen LLC ; Patricia Lloyd, US Food and Drug Administration; Cindy Ke Zhou, US Food and Drug Administration; An-Chi Lo, Acumen LLC; Yoganand Chillarige, Acumen LLC; John Hornberger, Acumen LLC; Jeffrey Kelman, Centers for Medicare & Medicaid Services; Anne Marie Kline, Aetna; Cheryl N McMahill-Walraven, Aetna; Kandace L. Amend, Optum Epidemiology; John D Seeger, Optum Epidemiology; Daniel Beachler, HealthCore, Inc.; Alex Secora, IQVIA; Christian Reich, IQVIA; Azadeh Shoaibi, US Food and Drug Administration; Hui Lee Wong, US Food and Drug Administration; Steven Anderson, US Food and Drug Administration
8:40 AM
Integration of Efficacy Biomarkers Together with Toxicity Endpoints in Immuno-Oncology Dose Finding Studies
Yiding Zhang, Sanofi ; Zhixing Xu, Sanofi; Ji Lin, Sanofi; Hui Quan, Sanofi
8:45 AM
Practical Implementation of Randomization in a Complex Site-Level Stepped-Wedge Cluster Pragmatic Randomized Trial
Wen Wan, Section of General Internal Medicine, University of Chicago ; Linda Rosul, Access community health network; Theodore Karrison, University of Chicago; Neda Laiteerapong, Section of General Internal Medicine, University of Chicago
8:50 AM
A Two-Stage Method to Minimize the Expected Sample Size of a Single-Arm Study Under the Alternative Hypothesis
Xiaobo Zhong, Bristol Myers Squibb ; Qian Li, Biostatistics and Strategic Consulting
8:55 AM
Improving Dose-Escalation Design with Historical and Concurrent Trial Data
Abhishek Kumar Dubey, Bristol Myer Squibb ; Arun Kumar Kumar, Bristol Myer Squibb; Kaushal Kumar Mishra, Bristol Myer Squibb
9:00 AM
BGLAM: A Bayesian General Logistic Autoregressive Model for Correlated Binary Outcomes
Ahmad Hakeem Abdul Wahab, Janssen Pharmaceuticals ; Arman Sabbaghi, Purdue University; Maggie O'Haire, Purdue University
9:05 AM
Practical Guidance on Mixture Priors Specification in Oncology Dose Escalation Models
Frank Shen, Bristol Myers Squibb ; Yanping Chen, Bristol Myers Squibb; Rong Liu, BMS
9:10 AM
Overlap Weight-Based Adaptive Bayesian Commensurate Prior for Augmenting the Control Arm of a Randomized Controlled Trial
Yeonil Kim, Merck & Co., Inc. ; Erina Paul, Merck & Co., Inc.
9:15 AM
Power Analysis for Longitudinal Cluster Randomized Trials with Binary Outcomes
Jijia Wang, UT Southwestern Medical Center
9:20 AM
Association of COVID Vaccine Hesitancy and Vaccine Misinformation Using Google Trends Analytics Vaccine Hesitancy
Lan Gao, The University of Tennessee at Chattanooga
9:30 AM
Extending the Weighted Generalized Score Statistic for Comparison of Correlated Means
Aaron D. Jones, Duke University ; Andrzej S. Kosinski, Duke University
9:35 AM
Can Cutaneous Squamous Cell Carcinoma Be Properly Graded? Investigation of the Differentiation Grading Among Dermatopathologists
Yevgeniya Gokun, The Ohio State University ; Xueliang Pan, The Ohio State University; David Carr, The Ohio State University; Katie Shahwan, The Ohio State University; Jessica Nash, The Ohio State University
9:45 AM
Homogeneity Test for Ordinal ROC Regression and Application to Facial Recognition
Ty Nguyen, University of Central Florida ; Larry Tang, University of Central Florida
9:50 AM
Club Exco: Clustering Brain Extreme Communities from Multi-Channel EEG Data
Matheus Bartolo Guerrero, King Abdullah University of Science and Technology ; Raphael Huser, King Abdullah University of Science and Technology (KAUST); Hernando Ombao, King Abdullah University of Science and Technology
9:55 AM
Large-Scale Correlation Screening Under Dependence for Brain Functional Connectivity Inference
Hanâ LBATH, Univ. Grenoble Alpes, CNRS, Inria, Grenoble INP, LJK ; Alexander Petersen, Brigham Young University; Sophie ACHARD, Univ. Grenoble Alpes, CNRS, Inria, Grenoble INP, LJK
10:00 AM
Correcting Under-Reporting in Cyber Incidents
Seema Sangari, Kennesaw State University ; Eric Dallal, Verisk
10:05 AM
Outcome-Dependent Sampling on Posterior Estimates of Salesperson Rankings
Neil Mercer, Google LLC ; Frank Yoon, Google LLC; Ignacio Martinez, Google LLC
10:10 AM
A Framework for Measuring Influencer Marketing
Gary Cohen, Amazon.com ; Vanja Dukic, Amazon.com
10:15 AM
Floor Discussion
398 * !
Wed, 8/10/2022,
10:30 AM -
12:20 PM
CC-202B
Recent Advances in Streaming Data Analytics — Invited Papers
International Chinese Statistical Association , WNAR, Section on Statistical Learning and Data Science
Organizer(s): Lan Luo, The University of Iowa
Chair(s): Peter Song, University of Michigan
10:35 AM
Multivariate Online Regression Analysis with Heterogeneous Streaming Data
Lan Luo, The University of Iowa ; Peter Song, University of Michigan
11:00 AM
Dynamic Statistical Inference in Massive Datastreams
Lilun Du, HKUST; Changliang Zou, Nankai University; Zhenke Wu, University of Michigan, Ann Arbor; Jingshen Wang, UC Berkeley
11:25 AM
Assessing Time-Varying Causal Effect Moderation in the Presence of Cluster-Level Treatment Effect Heterogeneity
Walter Dempsey, University of Michigan ; Zhenke Wu, University of Michigan, Ann Arbor; Jieru Shi, University of Michigan
11:50 AM
Statistical Inference for Online Decision-Making via Stochastic Gradient Descent
Rui Song, North Carolina State University
12:15 PM
Floor Discussion
408 * !
Wed, 8/10/2022,
10:30 AM -
12:20 PM
CC-144C
Recent Advances in Statistical Machine Learning — Topic Contributed Papers
Section for Statistical Programmers and Analysts , Section on Statistical Learning and Data Science, Section on Nonparametric Statistics, International Chinese Statistical Association
Organizer(s): Guan Yu, University of Pittsburgh
Chair(s): Gen Li, University of Michigan
10:35 AM
Locally Weighted Nearest Neighbor Classifier
Guan Yu, University of Pittsburgh ; Xingye Qiao, Binghamton University
10:55 AM
Contextual Dynamic Pricing with Unknown Noise
Yiyun Luo, UNC; Will Wei Sun, Purdue University ; Yufeng Liu, University of North Carolina
11:15 AM
Optimal and Safe Estimation for High-Dimensional, Semi-Supervised Learning
Yang Ning, Cornell University
11:35 AM
Learning Acceptance Regions for Many Classes with Anomaly Detection
Zhou Wang, Binghamton University; Xingye Qiao, Binghamton University
11:55 AM
Floor Discussion
443
Wed, 8/10/2022,
10:30 AM -
11:15 AM
CC-Hall D
SPEED: Statistical Methods and Applications in Medical Research, Risk Analysis, and Marketing Part 2 — Contributed Poster Presentations
Biopharmaceutical Section , Section on Medical Devices and Diagnostics, Section on Statistics in Imaging, IMS, International Chinese Statistical Association, Section on Risk Analysis, Section on Statistics in Marketing
Chair(s): Michael Higgins, Kansas State University
01:
Near Real-Time Surveillance of COVID-19 Vaccine Safety in the U.S. Food and Drug Administration Biologics Effectiveness and Safety (BEST) Initiative Data Network
Mao Hu, Acumen LLC ; Patricia Lloyd, US Food and Drug Administration; Cindy Ke Zhou, US Food and Drug Administration; An-Chi Lo, Acumen LLC; Yoganand Chillarige, Acumen LLC; John Hornberger, Acumen LLC; Jeffrey Kelman, Centers for Medicare & Medicaid Services; Anne Marie Kline, Aetna; Cheryl N McMahill-Walraven, Aetna; Kandace L. Amend, Optum Epidemiology; John D Seeger, Optum Epidemiology; Daniel Beachler, HealthCore, Inc.; Alex Secora, IQVIA; Christian Reich, IQVIA; Azadeh Shoaibi, US Food and Drug Administration; Hui Lee Wong, US Food and Drug Administration; Steven Anderson, US Food and Drug Administration
02:
Dose Finding via Efficacy Biomarkers and Toxicity Endpoints in Immuno-Oncology Clinical Trials
Yiding Zhang, Sanofi ; Zhixing Xu, Sanofi; Ji Lin, Sanofi; Hui Quan, Sanofi
03:
Practical Implementation of Randomization in a Complex Site-Level Stepped-Wedge Cluster Pragmatic Randomized Trial
Wen Wan, Section of General Internal Medicine, University of Chicago ; Linda Rosul, Access community health network; Theodore Karrison, University of Chicago; Neda Laiteerapong, Section of General Internal Medicine, University of Chicago
04:
A Two-Stage Method to Minimize the Expected Sample Size of a Single-Arm Study Under the Alternative Hypothesis
Xiaobo Zhong, Bristol Myers Squibb ; Qian Li, Biostatistics and Strategic Consulting
05:
Improving Dose-Escalation Design with Historical and Concurrent Trial Data
Abhishek Kumar Dubey, Bristol Myer Squibb ; Arun Kumar Kumar, Bristol Myer Squibb; Kaushal Kumar Mishra, Bristol Myer Squibb
06:
BGLAM: A Bayesian General Logistic Autoregressive Model for Correlated Binary Outcomes
Ahmad Hakeem Abdul Wahab, Janssen Pharmaceuticals ; Arman Sabbaghi, Purdue University; Maggie O'Haire, Purdue University
07:
Practical Guidance on Mixture Priors Specification in Oncology Dose Escalation Models
Frank Shen, Bristol Myers Squibb ; Yanping Chen, Bristol Myers Squibb; Rong Liu, BMS
08:
Overlap Weight-Based Adaptive Bayesian Commensurate Prior for Augmenting the Control Arm of a Randomized Controlled Trial
Yeonil Kim, Merck & Co., Inc. ; Erina Paul, Merck & Co., Inc.
09:
Power Analysis for Longitudinal Cluster Randomized Trials with Binary Outcomes
Jijia Wang, UT Southwestern Medical Center
10:
Association of COVID Vaccine Hesitancy and Vaccine Misinformation Using Google Trends Analytics Vaccine Hesitancy
Lan Gao, The University of Tennessee at Chattanooga
11:
Extending the Weighted Generalized Score Statistic for Comparison of Correlated Means
Aaron D. Jones, Duke University ; Andrzej S. Kosinski, Duke University
12:
Can Cutaneous Squamous Cell Carcinoma Be Properly Graded? Investigation of the Differentiation Grading Among Dermatopathologists
Yevgeniya Gokun, The Ohio State University ; Xueliang Pan, The Ohio State University; David Carr, The Ohio State University; Katie Shahwan, The Ohio State University; Jessica Nash, The Ohio State University
13:
Evaluation of Patient-Reported Outcomes Using Kappa Statistics
Saryet Kucukemiroglu, Food and Drug Administration; Manasi Sheth, Food and Drug Administration
14:
Statistical Considerations When Evaluating Diagnostic Devices with Categorical Output
Manasi Sheth, Food and Drug Administration
15:
Homogeneity Test for Ordinal ROC Regression and Application to Facial Recognition
Ty Nguyen, University of Central Florida ; Larry Tang, University of Central Florida
16:
Club Exco: Clustering Brain Extreme Communities from Multi-Channel EEG Data
Matheus Bartolo Guerrero, King Abdullah University of Science and Technology ; Raphael Huser, King Abdullah University of Science and Technology (KAUST); Hernando Ombao, King Abdullah University of Science and Technology
17:
Large-Scale Correlation Screening Under Dependence for Brain Functional Connectivity Inference
Hanâ LBATH, Univ. Grenoble Alpes, CNRS, Inria, Grenoble INP, LJK ; Alexander Petersen, Brigham Young University; Sophie ACHARD, Univ. Grenoble Alpes, CNRS, Inria, Grenoble INP, LJK
18:
Correcting Under-Reporting in Cyber Incidents
Seema Sangari, Kennesaw State University ; Eric Dallal, Verisk
19:
Outcome-Dependent Sampling on Posterior Estimates of Salesperson Rankings
Neil Mercer, Google LLC ; Frank Yoon, Google LLC; Ignacio Martinez, Google LLC
20:
A Framework for Measuring Influencer Marketing
Gary Cohen, Amazon.com ; Vanja Dukic, Amazon.com
471 !
Wed, 8/10/2022,
2:00 PM -
3:50 PM
CC-154A
New Frontier in Developments of Complex-Structured High-Dimensional Data Analysis — Topic Contributed Papers
International Chinese Statistical Association , IMS, Section on Statistics and Data Science Education
Organizer(s): Chenlu Ke, Virginia Commonwealth University; Jiaying Weng, Bentley University
Chair(s): Chenlu Ke, Virginia Commonwealth University
2:05 PM
Functional Group Lasso with Functional Predictor Selection
Jun Song, Korea University ; Ali Mahzarnia, UNC Charlotte
2:25 PM
Testing the Linear Mean and Constant Variance Conditions in Sufficient Dimension Reduction
Yuexiao Dong, Temple University
2:45 PM
Pseudo Sufficient Dimension Reduction with Ill-Conditioned Sample Covariance Matrix
Wenbo Wu, The University of Texas at San Antonio
3:05 PM
Subspace Estimation with Automatic Dimension and Variable Selection in Sufficient Dimension Reduction
Jing Zeng, Florida State University ; Qing Mai, Florida State University; Xin Zhang, Florida State University
3:25 PM
Triply Robust Surrogate-and-Model-Assisted Semi-Supervised Transfer Learning
Mengyan Li, Bentley University ; Tianxi Cai , Harvard University ; Molei Liu, Harvard University
3:45 PM
Floor Discussion
508 * !
Thu, 8/11/2022,
8:30 AM -
10:20 AM
CC-202A
Innovative Statistical Methods for Preclinical to Clinical Translatability in Drug Development — Topic Contributed Papers
Biopharmaceutical Section , Biometrics Section, International Chinese Statistical Association
Organizer(s): Dean Li, Pfizer
Chair(s): Dean Li, Pfizer
8:35 AM
Predicting Clinical Response Rate of BRAF Inhibitors in BRAF-Mutant Melanoma Using Preclinical Data
Shibing Deng, Pfizer Inc ; Douglas Robinson, Pfizer Inc
8:55 AM
A Bayesian Approach for MRE Back Translation Based Decision Making with the Attenuation Ratio Metric
Thomas Bradstreet, Bristol-Myers Squibb ; Haiying Tang, CHDI Management, Inc.; Matthew Fronheiser, Bristol-Myers Squibb; Thomas Petrone, Bristol-Myers Squibb; Lei Zhao, Bristol-Myers Squibb
9:15 AM
A Bayesian Gene Network Reveals Insight into the JAK-STAT Pathway in Systemic Lupus Erythematosus
Yushi Liu, Eli Lilly and Company
9:35 AM
Discussant: Alan Chiang, Lyell Immunopharma
9:55 AM
Floor Discussion
520
Thu, 8/11/2022,
8:30 AM -
10:20 AM
CC-141
Variable Selection, Model Selection, and Aggregated Inference — Contributed Papers
International Chinese Statistical Association
Chair(s): Shrabanti Chowdhury, Icahn school of Medicine at Mount Sinai
8:35 AM
Fréchet Sufficient Variable Selection with Graph Structure Among Predictors
Jiaying Weng, Bentley University
8:50 AM
Sufficient Dimension Folding with Categorical Predictors
Qingcong Yuan, Miami University ; Yuanwen Wang, Apple; Yuan Xue, University of International Business and Economics
9:05 AM
Confidence Envelopes for Model Selection Inference and Post Model Selection Inference
Lakmini Nadeesha Jayaweera Imiya Mohottige, Texas Tech University ; Adao Alex Trindade, Texas Tech University
9:20 AM
Minimum Discrepancy Approach for Dimension Reduction by Feature Filter
Pei Wang, Miami of Ohio
9:35 AM
Robust Tests for Combining P-Values Under Arbitrary Dependency Structures
Zhongxue Chen, Indiana University Bloomington
9:50 AM
The Poisson Multinomial Distribution and Its Applications in Voting Theory, Ecological Inference, and Machine Learning
ZHENGZHI LIN, Virginia Tech
10:05 AM
When to Initiate Cancer Screening Exam If Sensitivity Is a Function of Sojourn Time?
Dongfeng Wu, University of Louisville