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374 * ! Wed, 8/10/2022, 8:30 AM - 10:20 AM CC-201
Bayesian Clinical Trial Designs with Heterogeneous Patient Subgroups — Topic Contributed Papers
Biopharmaceutical Section, International Chinese Statistical Association, Section on Bayesian Statistical Science
Organizer(s): Kentaro Takeda, Astellas Pharma Global Development, Inc.
Chair(s): Kentaro Takeda, Astellas Pharma Global Development, Inc.
8:35 AM Dose Finding with Heterogeneous Patient Subgroups
ANASTASIA IVANOVA, UNC at Chapel Hill; Pooja Saha, Center for Biostatistics in AIDS Research, Department of Biostatistics, Harvard T.H. Chan
8:55 AM Group-Sequential Enrichment Designs Based on Adaptive Regression of Response and Survival Time on High-Dimensional Covariates
Yeonhee Park, University of Wisconsin-Madison; Suyu Liu, The University of Texas MD Anderson Cancer Center; Peter Thall, The University of Texas MD Anderson Cancer Center; Ying Yuan , the University of Texas MD Anderson Cancer Center
9:15 AM BAGS: A Bayesian Adaptive Group Sequential Trial Design with Subgroup-Specific Survival Comparisons
Ruitao Lin, MD Anderson; Peter Thall, The University of Texas MD Anderson Cancer Center; Ying Yuan , the University of Texas MD Anderson Cancer Center
9:35 AM Bayesian Divide-and-Conquer Propensity Score–Based Approaches for Leveraging Real-World Data in Randomized Control Trials
Eric Baron, University of Connecticut; Jian Zhu, Servier Pharmaceuticals; Sammi Tang, Servier Pharmaceuticals; Ming-Hui Chen, University of Connecticut
9:55 AM Incorporating Historical Information for Randomized Clinical Trials: Dynamic Borrowing with Bias Control
Masataka Taguri, Yokohama City University
10:15 AM Floor Discussion