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217 * ! Tue, 8/9/2022, 8:30 AM - 10:20 AM CC-150B
Theory and Algorithms for Adaptive Clinical Trial Design with Multiple Objectives — Invited Papers
WNAR, International Chinese Statistical Association, Biopharmaceutical Section
Organizer(s): Ying Lu, Stanford University School of Medicine
Chair(s): Ying Lu, Stanford University School of Medicine
8:35 AM Grammar of Group Sequential Design
Keaven M Anderson, Merck & Co., Inc.; Yilong Zhang, Merck & Co., Inc.; Nan Xiao, Merck & Co., Inc.; Yujie Zhao, Merck & Co., Inc.
9:00 AM Tight, Rigorous, and Automated Type I Error Proofs with Simulation
Michael Benjamin Sklar, Stanford University
9:25 AM Optimizing Patient Enrollment in Global Clinical Trials by Metaheuristics
Weng Kee Wong, UCLA; Mitchell Schepps, UCLA; Austin Matt, Amgen; Vlad Anisimov, Amgen
9:50 AM Multi-Objective Approach to Assist in Selection of Efficient Clinical Trial Operation Design with Respect to Minimizing Expected Recruitment Time and the Geographic Site Footprint
Austin Matt, Amgen; Vlad Anisimov, Amgen
10:15 AM Floor Discussion