Conference Program Home
  My Program

All Times EDT

Legend:
CC = Walter E. Washington Convention Center   M = Marriott Marquis Washington, DC
* = applied session       ! = JSM meeting theme

Activity Details


119 * !
Mon, 8/8/2022, 10:30 AM - 12:20 PM CC-151B
Statistics for Mobile and Wearable Device Data — Invited Papers
Business and Economic Statistics Section, Section on Medical Devices and Diagnostics, Section on Statistics in Epidemiology
Organizer(s): Nathaniel Josephs, Yale University
Chair(s): Nathaniel Josephs, Yale University
10:35 AM Impact of Close Interpersonal Contact on COVID-19 Incidence: Evidence from One Year of Mobile Device Data
Forrest W. Crawford, Yale University; Sydney A. Jones, CDC/CT DPH; Matthew Cartter, CT DPH; Samantha Dean, Yale School of Public Health; Joshua L. Warren, Yale School of Public Health; Zehang Richard Li, UCSC; Jacqueline Barbieri, Whitespace Ltd; Jared Campbell, Whitespace Ltd; Patrick Kenney, Whitespace Ltd; Thomas Valleau, Whitespace Ltd; Olga Morozova, Stony Brook University
11:00 AM Significance Testing in Four-Period Crossover Designs, with Application to Physical Activity Data in Cats
Ana-Maria Staicu, North Carolina State University; Salil Koner, University of Pennsylvania
11:25 AM Smartphone-Based Human Activity Recognition
Jukka-Pekka Onnela, Harvard T.H. Chan School of Public Health
11:50 AM Discussant: Eric Kolaczyk, Boston University
12:10 PM Floor Discussion
 
 

193 *
Mon, 8/8/2022, 2:00 PM - 3:50 PM CC-204B
Section on Medical Devices and Diagnostics: Student Paper Competition — Topic Contributed Papers
Section on Medical Devices and Diagnostics
Organizer(s): Tracy Bergemann, Medtronic Plc
Chair(s): Tracy Bergemann, Medtronic Plc
2:05 PM Batch Bayesian Optimization Design for Optimizing a Neurostimulator
Adam Kaplan , Center for Care Delivery and Outcomes Research ; Thomas Murray , University of Minnesota
2:25 PM Deep Spectral Q-Learning in Infinite Horizon with Applications in Mobile Health
Yuhe Gao, North Carolina State University; Chengchun Shi, London School of Economics and Political Science; Rui Song, North Carolina State University
2:45 PM Modeling and Estimating a Threshold Effect: An Application to Improving Cardiac Surgery Practices
Guangyu Yang, University of Michigan; Baqun Zhang, Shanghai University of Finance and Economics; Jonathan Haft, University of Michigan; Robert Hawkins, University of Michigan; David Sturmer, University of Michigan; Donald Likosky, University of Michigan; Min Zhang, University of Michigan
3:05 PM A Single Index Model for Longitudinal Outcomes to Optimize Individual Treatment Decision Rules
Lanqiu Yao, New York University School of Medicine; Thaddeus Tarpey, New York University
3:25 PM Estimating the Lifetime Risk of a False Positive Screening Test Result Presentation
Tim White, University of Minnesota; Sara Algeri, University of Minnesota
3:45 PM Floor Discussion
 
 

246
Tue, 8/9/2022, 8:30 AM - 10:20 AM CC-140A
Improved Disease Classification Through Extensions of ROC Curve Estimation and Biomarker Characterization — Contributed Papers
Section on Medical Devices and Diagnostics
Chair(s): Roseann White, Natera
8:35 AM Parametric and Semiparametric Multiple Imputation for Missing Biomarker Values
Peng Shi, University of Kansas Medical Center; Leonidas Bantis, University of Kansas Medical Center
8:50 AM Sampling Bias Adjustment for Bridging Efficacy from Multiple Clinical Trial Assays (CTA) to a Companion Diagnostics Assay (CDx)
Ja-An Lin, Illumina Inc; Yaji Xu, Illumina Inc; Aida Yazdanparast, Illumina Inc; Johan Surtihadi, Illumina Inc
9:05 AM Diagnostic Latent Class Model for Ordinal Classification
Xiaoyan Lin, University of South Carolina; Yun Yang, University of South Carolina; Kerrie Nelson, Boston University School of Public Health
9:20 AM Predicting Type 2 Diabetes Based on Multiclass AUC from Multinomial Logistic Regression Presentation
Paul G Wakim, NIH Clinical Center; Hima Tallam, NIH Clinical Center; Daniel C Elton, NIH Clinical Center; Sungwon Lee, NIH Clinical Center; Perry J Pickhardt, University of Wisconsin School of Medicine and Public Health; Ronald M Summers, NIH Clinical Center
9:35 AM Analyzing Partially Paired Data for Diagnostic Radiology Studies Using the Obuchowski-Rockette Method
Stephen L Hillis, ASA
9:50 AM Estimating Diagnostic Accuracy When Candidate Tests Are Subject to Detection Limits---Application to Diagnosing Early Stage Alzheimer Disease
Chengjie Xiong, Division of Biostatistics, Washington University in St. Louis; Jingqin Luo, Division of Public Health Sciences, Washington University in St. Louis; John Morris, Knight Alzheimer Disease Research Center, Washington University in St. Louis
10:05 AM Estimation and Inference on the Volume Under the ROC Surface in a Clinical Region of Interest
Kate Young, University of Kansas Medical Center; Leonidas Bantis, University of Kansas Medical Center
 
 

265 * !
Tue, 8/9/2022, 10:30 AM - 12:20 PM CC-143C
Stochastic Processes in Medicine and Medical Engineering: Theoretical Foundations and Applications — Topic Contributed Papers
Section on Medical Devices and Diagnostics, IMS, Section on Physical and Engineering Sciences
Organizer(s): Jan Beran, University of Konstanz
Chair(s): Sucharita Ghosh, Swiss Federal Research Institute WSL
10:35 AM Functional Time Series Modeling of Mechanically Ventilated Breathing Activity
Jan Beran, University of Konstanz
10:55 AM Scalable Gaussian Process Regression for Biomedical Time-Series Data
Jan Graßhoff, Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering; Philipp Rostalski, Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering
11:15 AM Incorporating Model Mismatch in a Bayesian Uncertainty Quantification Analysis of a Fluid-Dynamics Model of Pulmonary Blood Circulation Presentation
Mihaela Paun, University of Glasgow; Mitchel Colebank, University of California; Mette Olufsen, North Carolina State University; Nicholas Hill, University of Glasgow; Dirk Husmeier, University of Glasgow
11:35 AM Adaptive Frequency Band Analysis for Multivariate Biomedical Time Series
Scott Alan Bruce, Texas A&M University; Raanju Sundararajan, Southern Methodist University
11:55 AM Benefits of Noise in Biomedical Research: A Multiscale Point of View
Brani Vidakovic, Texas A&M University
12:15 PM Floor Discussion
 
 

292
Tue, 8/9/2022, 10:30 AM - 12:20 PM CC-Hall D
Contributed Poster Presentations: Section on Medical Devices and Diagnostics — Contributed Poster Presentations
Section on Medical Devices and Diagnostics
Chair(s): Gyuhyeong Goh, Kansas State University
42: Adaptive Learning Algorithms for Functional Data Analysis of Accelerometry Data
Margaret Banker, University of Michigan; Peter Song, University of Michigan
43: Re-Calibration the Right and Fair Way
Bertrand Haas, Amazon
 
 

319 * !
Tue, 8/9/2022, 2:00 PM - 3:50 PM CC-207B
Innovative Statistical and Machine Learning Methods for Wearable Device Data — Topic Contributed Papers
WNAR, Section on Medical Devices and Diagnostics, ENAR
Organizer(s): Chongzhi Di, Fred Hutchinson Cancer Research Center; Ken Wang, Fred Hutchinson Cancer Research Center
Chair(s): Jingjing Zou, University of California at San Diego (UCSD)
2:05 PM Sedentary Behavior Estimation with Hip-worn Accelerometer Data: Segmentation, Classification and Thresholding
Loki Natarajan, University of California at San Diego (UCSD); Jingjing Zou, University of California at San Diego (UCSD); Yiren Wang, University of California San Diego
2:25 PM Considerations to Address Missing Data When Deriving Clinical Trial Endpoints from Digital Health Technologies
Junrui Di, Pfizer Inc
2:45 PM Identifying Different Patterns Across Multiple Activity Behaviors Using Latent Class Analysis: A Compositional Data Approach
Annie Green Howard, UNC - Chapel Hill; Fang Wen, UNC - Chapel Hill; Chongzhi Di, Fred Hutchinson Cancer Research Center; Julie Buring, Harvard Medical School; Eric Shiroma, National Institute on Aging; Michael Kebede, UNC - Chapel HIll; Kelly Evenson, UNC - Chapel Hill; I-Min Lee, Harvard T.H. Chan School of Public Health
3:05 PM Calibration of an Accelerometer Activity Index Among Older Women and Its Association with Cardiometabolic Risk Factors
Guangxing Wang, Fred Hutchinson Cancer Research Center; Sixuan Wu, Inspur; Kelly Evenson, UNC - Chapel Hill; Ilsuk Kang, Fred Hutchinson Cancer Research Center; Michael LaMonte, University at Buffalo – SUNY; John Bellettiere, UCSD; I-Min Lee, Harvard T.H. Chan School of Public Health; Annie Green Howard, UNC - Chapel Hill; Andrea LaCroix, UCSD; Chongzhi Di, Fred Hutchinson Cancer Research Center
3:25 PM Discussant: Chongzhi Di, Fred Hutchinson Cancer Research Center
3:45 PM Floor Discussion
 
 

385
Wed, 8/10/2022, 8:30 AM - 10:20 AM CC-140A
SPEED: Statistical Methods and Applications in Medical Research, Risk Analysis, and Marketing Part 1 — Contributed Speed
Biopharmaceutical Section, Section on Medical Devices and Diagnostics, Section on Statistics in Imaging, IMS, International Chinese Statistical Association, Section on Risk Analysis, Section on Statistics in Marketing
Chair(s): Michael Higgins, Kansas State University
8:35 AM Near Real-Time Surveillance of COVID-19 Vaccine Safety in the U.S. Food and Drug Administration Biologics Effectiveness and Safety (BEST) Initiative Data Network
Mao Hu, Acumen LLC; Patricia Lloyd, US Food and Drug Administration; Cindy Ke Zhou, US Food and Drug Administration; An-Chi Lo, Acumen LLC; Yoganand Chillarige, Acumen LLC; John Hornberger, Acumen LLC; Jeffrey Kelman, Centers for Medicare & Medicaid Services; Anne Marie Kline, Aetna; Cheryl N McMahill-Walraven, Aetna; Kandace L. Amend, Optum Epidemiology; John D Seeger, Optum Epidemiology; Daniel Beachler, HealthCore, Inc.; Alex Secora, IQVIA; Christian Reich, IQVIA; Azadeh Shoaibi, US Food and Drug Administration; Hui Lee Wong, US Food and Drug Administration; Steven Anderson, US Food and Drug Administration
8:40 AM Integration of Efficacy Biomarkers Together with Toxicity Endpoints in Immuno-Oncology Dose Finding Studies
Yiding Zhang, Sanofi; Zhixing Xu, Sanofi; Ji Lin, Sanofi; Hui Quan, Sanofi
8:45 AM Practical Implementation of Randomization in a Complex Site-Level Stepped-Wedge Cluster Pragmatic Randomized Trial
Wen Wan, Section of General Internal Medicine, University of Chicago; Linda Rosul, Access community health network; Theodore Karrison, University of Chicago; Neda Laiteerapong, Section of General Internal Medicine, University of Chicago
8:50 AM A Two-Stage Method to Minimize the Expected Sample Size of a Single-Arm Study Under the Alternative Hypothesis
Xiaobo Zhong, Bristol Myers Squibb; Qian Li, Biostatistics and Strategic Consulting
8:55 AM Improving Dose-Escalation Design with Historical and Concurrent Trial Data
Abhishek Kumar Dubey, Bristol Myer Squibb; Arun Kumar Kumar, Bristol Myer Squibb; Kaushal Kumar Mishra, Bristol Myer Squibb
9:00 AM BGLAM: A Bayesian General Logistic Autoregressive Model for Correlated Binary Outcomes
Ahmad Hakeem Abdul Wahab, Janssen Pharmaceuticals; Arman Sabbaghi, Purdue University; Maggie O'Haire, Purdue University
9:05 AM Practical Guidance on Mixture Priors Specification in Oncology Dose Escalation Models
Frank Shen, Bristol Myers Squibb; Yanping Chen, Bristol Myers Squibb; Rong Liu, BMS
9:10 AM Overlap Weight-Based Adaptive Bayesian Commensurate Prior for Augmenting the Control Arm of a Randomized Controlled Trial
Yeonil Kim, Merck & Co., Inc. ; Erina Paul, Merck & Co., Inc.
9:15 AM Power Analysis for Longitudinal Cluster Randomized Trials with Binary Outcomes
Jijia Wang, UT Southwestern Medical Center
9:20 AM Association of COVID Vaccine Hesitancy and Vaccine Misinformation Using Google Trends Analytics Vaccine Hesitancy
Lan Gao, The University of Tennessee at Chattanooga
9:30 AM Extending the Weighted Generalized Score Statistic for Comparison of Correlated Means
Aaron D. Jones, Duke University; Andrzej S. Kosinski, Duke University
9:35 AM Can Cutaneous Squamous Cell Carcinoma Be Properly Graded? Investigation of the Differentiation Grading Among Dermatopathologists
Yevgeniya Gokun, The Ohio State University; Xueliang Pan, The Ohio State University; David Carr, The Ohio State University; Katie Shahwan, The Ohio State University; Jessica Nash, The Ohio State University
9:45 AM Homogeneity Test for Ordinal ROC Regression and Application to Facial Recognition
Ty Nguyen, University of Central Florida; Larry Tang, University of Central Florida
9:50 AM Club Exco: Clustering Brain Extreme Communities from Multi-Channel EEG Data
Matheus Bartolo Guerrero, King Abdullah University of Science and Technology; Raphael Huser, King Abdullah University of Science and Technology (KAUST); Hernando Ombao, King Abdullah University of Science and Technology
9:55 AM Large-Scale Correlation Screening Under Dependence for Brain Functional Connectivity Inference
Hanâ LBATH, Univ. Grenoble Alpes, CNRS, Inria, Grenoble INP, LJK; Alexander Petersen, Brigham Young University; Sophie ACHARD, Univ. Grenoble Alpes, CNRS, Inria, Grenoble INP, LJK
10:00 AM Correcting Under-Reporting in Cyber Incidents
Seema Sangari, Kennesaw State University; Eric Dallal, Verisk
10:05 AM Outcome-Dependent Sampling on Posterior Estimates of Salesperson Rankings
Neil Mercer, Google LLC; Frank Yoon, Google LLC; Ignacio Martinez, Google LLC
10:10 AM A Framework for Measuring Influencer Marketing
Gary Cohen, Amazon.com; Vanja Dukic, Amazon.com
10:15 AM Floor Discussion
 
 

400 * !
Wed, 8/10/2022, 10:30 AM - 12:20 PM CC-151B
Challenges and Opportunities for the Principled Calibration and QA/QC Assessments of AI and Machine Learning Methods Within Medical Device Applications — Invited Papers
Section on Medical Devices and Diagnostics, International Indian Statistical Association, American Medical Informatics Association
Organizer(s): Arvind Rao, University of Michigan
Chair(s): Ja-An Lin, Illumina Inc
10:35 AM Validation of Machine Learning-Enabled Diagnostic Medical Devices: Statistical Challenges and Opportunities from a Regulatory Perspective Presentation
Gene Anthony Pennello, Food and Drug Administration
10:55 AM Quality Assessment of AI Tools in Radiology
Arvind Rao, University of Michigan
11:15 AM Advancing Regulatory Science for Medical Devices and Medical Software Through Collaboration
Jithesh Veetil, PhD, MDIC
11:35 AM Modifying Artificial Intelligence/Machine Learning-Based Software and the Algorithm Change Protocol
Tarek Haddad, Medtronic Inc.; Donald Musgrove, Medtronic Inc.
11:55 AM Discussant: Tracy Bergemann, Medtronic Plc
12:15 PM Floor Discussion
 
 

443
Wed, 8/10/2022, 10:30 AM - 11:15 AM CC-Hall D
SPEED: Statistical Methods and Applications in Medical Research, Risk Analysis, and Marketing Part 2 — Contributed Poster Presentations
Biopharmaceutical Section, Section on Medical Devices and Diagnostics, Section on Statistics in Imaging, IMS, International Chinese Statistical Association, Section on Risk Analysis, Section on Statistics in Marketing
Chair(s): Michael Higgins, Kansas State University
01: Near Real-Time Surveillance of COVID-19 Vaccine Safety in the U.S. Food and Drug Administration Biologics Effectiveness and Safety (BEST) Initiative Data Network
Mao Hu, Acumen LLC; Patricia Lloyd, US Food and Drug Administration; Cindy Ke Zhou, US Food and Drug Administration; An-Chi Lo, Acumen LLC; Yoganand Chillarige, Acumen LLC; John Hornberger, Acumen LLC; Jeffrey Kelman, Centers for Medicare & Medicaid Services; Anne Marie Kline, Aetna; Cheryl N McMahill-Walraven, Aetna; Kandace L. Amend, Optum Epidemiology; John D Seeger, Optum Epidemiology; Daniel Beachler, HealthCore, Inc.; Alex Secora, IQVIA; Christian Reich, IQVIA; Azadeh Shoaibi, US Food and Drug Administration; Hui Lee Wong, US Food and Drug Administration; Steven Anderson, US Food and Drug Administration
02: Dose Finding via Efficacy Biomarkers and Toxicity Endpoints in Immuno-Oncology Clinical Trials
Yiding Zhang, Sanofi; Zhixing Xu, Sanofi; Ji Lin, Sanofi; Hui Quan, Sanofi
03: Practical Implementation of Randomization in a Complex Site-Level Stepped-Wedge Cluster Pragmatic Randomized Trial
Wen Wan, Section of General Internal Medicine, University of Chicago; Linda Rosul, Access community health network; Theodore Karrison, University of Chicago; Neda Laiteerapong, Section of General Internal Medicine, University of Chicago
04: A Two-Stage Method to Minimize the Expected Sample Size of a Single-Arm Study Under the Alternative Hypothesis
Xiaobo Zhong, Bristol Myers Squibb; Qian Li, Biostatistics and Strategic Consulting
05: Improving Dose-Escalation Design with Historical and Concurrent Trial Data
Abhishek Kumar Dubey, Bristol Myer Squibb; Arun Kumar Kumar, Bristol Myer Squibb; Kaushal Kumar Mishra, Bristol Myer Squibb
06: BGLAM: A Bayesian General Logistic Autoregressive Model for Correlated Binary Outcomes
Ahmad Hakeem Abdul Wahab, Janssen Pharmaceuticals; Arman Sabbaghi, Purdue University; Maggie O'Haire, Purdue University
07: Practical Guidance on Mixture Priors Specification in Oncology Dose Escalation Models
Frank Shen, Bristol Myers Squibb; Yanping Chen, Bristol Myers Squibb; Rong Liu, BMS
08: Overlap Weight-Based Adaptive Bayesian Commensurate Prior for Augmenting the Control Arm of a Randomized Controlled Trial
Yeonil Kim, Merck & Co., Inc. ; Erina Paul, Merck & Co., Inc.
09: Power Analysis for Longitudinal Cluster Randomized Trials with Binary Outcomes
Jijia Wang, UT Southwestern Medical Center
10: Association of COVID Vaccine Hesitancy and Vaccine Misinformation Using Google Trends Analytics Vaccine Hesitancy
Lan Gao, The University of Tennessee at Chattanooga
11: Extending the Weighted Generalized Score Statistic for Comparison of Correlated Means
Aaron D. Jones, Duke University; Andrzej S. Kosinski, Duke University
12: Can Cutaneous Squamous Cell Carcinoma Be Properly Graded? Investigation of the Differentiation Grading Among Dermatopathologists
Yevgeniya Gokun, The Ohio State University; Xueliang Pan, The Ohio State University; David Carr, The Ohio State University; Katie Shahwan, The Ohio State University; Jessica Nash, The Ohio State University
13: Evaluation of Patient-Reported Outcomes Using Kappa Statistics
Saryet Kucukemiroglu, Food and Drug Administration; Manasi Sheth, Food and Drug Administration
14: Statistical Considerations When Evaluating Diagnostic Devices with Categorical Output
Manasi Sheth, Food and Drug Administration
15: Homogeneity Test for Ordinal ROC Regression and Application to Facial Recognition
Ty Nguyen, University of Central Florida; Larry Tang, University of Central Florida
16: Club Exco: Clustering Brain Extreme Communities from Multi-Channel EEG Data
Matheus Bartolo Guerrero, King Abdullah University of Science and Technology; Raphael Huser, King Abdullah University of Science and Technology (KAUST); Hernando Ombao, King Abdullah University of Science and Technology
17: Large-Scale Correlation Screening Under Dependence for Brain Functional Connectivity Inference
Hanâ LBATH, Univ. Grenoble Alpes, CNRS, Inria, Grenoble INP, LJK; Alexander Petersen, Brigham Young University; Sophie ACHARD, Univ. Grenoble Alpes, CNRS, Inria, Grenoble INP, LJK
18: Correcting Under-Reporting in Cyber Incidents
Seema Sangari, Kennesaw State University; Eric Dallal, Verisk
19: Outcome-Dependent Sampling on Posterior Estimates of Salesperson Rankings
Neil Mercer, Google LLC; Frank Yoon, Google LLC; Ignacio Martinez, Google LLC
20: A Framework for Measuring Influencer Marketing
Gary Cohen, Amazon.com; Vanja Dukic, Amazon.com
 
 

470 * !
Wed, 8/10/2022, 2:00 PM - 3:50 PM CC-207B
Beyond Precision Medicine: Making It Personal with N-of-1 and Single Case Methods for Medicine, Rare Diseases, Digital Health, Behavior, and Wearables — Topic Contributed Papers
Biometrics Section, Section on Medical Devices and Diagnostics, Mental Health Statistics Section
Organizer(s): Eric J. Daza, Evidation Health
Chair(s): Ziwei Liao, Columbia University
2:05 PM Efficient Sequential N-of-1 Trials and Observational Studies
Nicholas Schork, The Translational Genomics Research Institute
2:25 PM Using Population Crossover Trials to Improve the Decision Process Regarding Treatment Individualization in N-of-1 Trials Presentation
Francisco J. Diaz, The University of Kansas Medical Center
2:45 PM Experiences with Large Series of Individual Trials for Personalized Health Presentation
Christopher Schmid, Brown University
3:05 PM Single Case Designs: MVA’: A Mobile Application for Conducting Single-Case Experimental Research Remotely
Mariola Moeyaert, University at Albany
3:25 PM Individual Average Treatment Effect Estimation Using Real-World Observational Data from Wearables Presentation
Eric J. Daza, Evidation Health; Logan Schneider, Alphabet Inc.
3:45 PM Floor Discussion
 
 

548 !
Thu, 8/11/2022, 10:30 AM - 12:20 PM CC-151B
Innovative Methods in Precision Medicine — Topic Contributed Papers
Biometrics Section, Biopharmaceutical Section, Section on Medical Devices and Diagnostics
Organizer(s): David Gold, Amgen, Inc.
Chair(s): David Gold, Amgen, Inc.
10:35 AM Adjusting for Misclassification in a Stratified Biomarker Clinical Trial
Susan Halabi, Duke University School of Medicine
10:55 AM Estimation Following Two-Stage Adaptive Enrichment Design
Peter Kimani, Warwick Medical School
11:15 AM Subgroup Identification in Clinical Trial
Xin Huang, AbbVie Inc.
11:35 AM Pharmacogenomics for Tailored Therapies in Labeling of FDA Oncology Drugs
Danni Yu, Nektar Therapeutics
11:55 AM Discussant: Kay Tatsuoka, Santen