JSM 2012 Home

JSM 2012 Online Program

The views expressed here are those of the individual authors and not necessarily those of the JSM sponsors, their officers, or their staff.

Online Program Home

Activity Details

404 * Tue, 7/31/2012, 2:00 PM - 3:50 PM CC-Room 25A
Adaptive Designs with Applications in Phase I/II Trials — Contributed Papers
Biopharmaceutical Section
Chair(s): Annpey Pong, Merck
2:05 PM Bayesian Adaptive Phase II Trial Combining Proof of Concept and Dose-Finding: Comparison of Potential Models — Katherine Kacena, Aptiv Solutions ; Robert Noble, Aptiv Solutions ; Ping Chen, Aptiv Solutions ; Richard A Brigandi, GlaxoSmithKline
2:20 PM A Phase I Bayesian Adaptive Design to Simultaneously Optimize Dose and Schedule Among and Within Patients Jin Zhang, University of Michigan ; Thomas M Braun, University of Michigan
2:35 PM A Bayesian Phase I/II Trial Design with Delayed Outcomes Ick Hoon Jin, MD Anderson Cancer Center ; Ying Yuan, MD Anderson Cancer Center
2:50 PM A Phase I Trial Design for Incorporating Efficacy Outcomes That are Conditional Upon Absence of Dose-Limiting Toxicities Shan Kang, University of Michigan ; Thomas M Braun, University of Michigan ; Jeremy Michael George Taylor, University of Michigan
3:05 PM Two-stage futility analysis in phase III adaptive trials with time-to-event endpoint Xiaoyun (Nicole) Li, Merck & Co. ; Cong Chen, Merck
3:20 PM Web-EWOC: Interactive Web Tool for Designing and Conducting Dose-Finding Trials in Cancer Dror Berel, Cedars Sinai Medical Center ; Andre Rogatko, Cedars Sinai Medical Center ; Shao-Chi Huang, Cedars Sinai Medical Center ; Haibin Wang, Cedars Sinai Medical Center ; Galen Cook-Wiens, Cedars Sinai Medical Center ; Mourad Tighiouart, Cedars Sinai Medical Center
3:35 PM Phase III Design for Continuous Responses with an Adaptive Tuning Parameter Aleksandra Stein, University of Nebraska ; Aleksandra Stein, University of Nebraska

2012 JSM Online Program Home

For information, contact jsm@amstat.org or phone (888) 231-3473.

If you have questions about the Continuing Education program, please contact the Education Department.