JSM Activity #92

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Activity ID:  92
* Issues Relating to Crossover Trials
Date / Time / Room Sponsor Type
10:30 AM - 12:20 PM
Room: H-Murray Hill Suite B
Biometrics Section*, Biopharmaceutical Section*, ENAR Topic Contributed
Organizer: Lynn Wei, Merck & Company, Inc.; Xun Chen, Merck Research Laboratories
Chair: Hui Quan, Merck Research Laboratories
Floor Discussion 12:15 PM

Crossover design is often used in clinical trials including phase I pharmacokinetic trials and other phase trials in chronic disease. This session discusses issues related to design and analysis of cross-over trials and includes 5 presentations by speakers from both academia adn industry. Topics include practical issues in planning crossover trials in drug development, a non-parametric procedure, a more powerful bioequivalence analysis procedure, robustness of estimators, and an automated system for non-statisticians.
  301080  By:  Xun  Chen 10:35 AM 08/12/2002
A Note on ANOVA Assumptions and Robust Analysis for a Crossover Study

  301088  By:  Donghui  Zhang 10:55 AM 08/12/2002
A Highly Automated Crossover Study Analysis System for Non-statisticians

  301120  By:  Stephen J. Senn 11:15 AM 08/12/2002
Practical Issues in Planning Cross-over Trials in Drug Development

  301134  By:  Devan V. Mehrotra 11:35 AM 08/12/2002
A More Powerful Average Bioequivalence Analysis for the 2x2 Crossover

  301149  By:  Francois  Bellavance 11:55 AM 08/12/2002
A Nonparametric Procedure for the Analysis of Balanced Crossover Designs

JSM 2002

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Revised March 2002