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Wayne Nelson

Wayne Nelson Statistical Consulting



500 – Noninferiority and Equivalence Trials

Get More Information from Recurrent Events Data

Sponsor: Biopharmaceutical Section
Keywords: recurrent events, use all recurrences, disease recurrences, medical trials

Wayne Nelson

Wayne Nelson Statistical Consulting

Recurrent-events data arise in biomedical, engineering, sociological, business, and many other applications. Despite over 25 years of literature articles and books (e.g., Nelson 2003, Cook and Lawless, 2007) on analysis of such data, some current medical studies of recurrent diseases use only each patient's first occurrence time and ignore subsequent ones. This talk provides new results on how much information this poor practice loses and urges the use of all recurrences. Cook, R.J. and Lawless, J.F. (2007), The Statistical Analysis of Recurrent Events, 420 pp., Springer, New York. Nelson, Wayne B. (2003), Recurrent Events Data Analysis for Product Repairs, Disease Recurrences, and Other Applications, 151 pp., ASA-SIAM Series, SIAM, Philadelphia.

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