368 – Methods and Applications in High-Dimensional Data, Part 1
Assessing Variability of RNA Molecule Crystallizations
Ryan Rahrig
Ohio Northern University
A method is described for detecting local conformational changes between two 3D structures of the same RNA. These structures may be crystallizations from the same molecule from the same organism, or they may be crystallizations of molecules from di?erent,yet related, organisms. In this approach, we study the variability that exists among the translation and rotation that are needed to superimpose local neighborhoods after global superposition. Each translation is represented by a three-dimensional vector as is each rotation. Thus, we investigate the variability that exists among sets of multivariate data.