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121 * ! Mon, 8/9/2021, 1:30 PM - 3:20 PM Virtual
In the Pipeline: Statistical Advances to Preserve Biological Signal in High-Throughput, Single-Cell Imaging and Sequencing Methods — Topic-Contributed Papers
Section on Statistics in Imaging, Section on Statistics in Genomics and Genetics, ENAR
Organizer(s): Coleman R Harris, Vanderbilt University Medical Center
Chair(s): Simon N Vandekar, Vanderbilt University
1:35 PM ComBat-Seq: Batch Effect Adjustment for RNA-Seq Count Data
W. Evan Johnson, Boston University School of Medicine; Yuqing Zhang, Gilead Sciences, Inc.; Giovanni Parmigiani, Harvard University
1:55 PM Comparison of Normalization Methods to Combine Batches of High-Dimensional Multiplexed Images
Coleman R Harris, Vanderbilt University Medical Center; Qi Liu, Vanderbilt University Medical Center; Eliot McKinley, Vanderbilt University Medical Center; Joseph Roland, Vanderbilt University Medical Center; Ken Lau, Vanderbilt University Medical Center; Robert Coffey, Vanderbilt University Medical Center; Simon N Vandekar, Vanderbilt University
2:15 PM Design and Analysis of High-Throughput Cell Imaging Studies
Johann Gagnon-Bartsch, University of Michigan; Gregory Hunt, College of William & Mary
2:35 PM Robust Re-Scaling of Imaging Data to Improve Discovery of Latent Effects
Gregory Hunt, College of William & Mary; Johann Gagnon-Bartsch, University of Michigan
2:55 PM Back to the Future: Viewing Single-Cell Assays Through the Lens of Chromatin Structure
Timothy J. Triche, Van Andel Institute; Benjamin K Johnson, Van Andel Institute; Hui J Shen, Van Andel Institute
3:15 PM Floor Discussion