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Activity Number: 82 - Evaluating Causal Effects Using Incomplete Data with Interference in Public Health Research
Type: Topic-Contributed
Date/Time: Monday, August 9, 2021 : 10:00 AM to 11:50 AM
Sponsor: ENAR
Abstract #317329
Title: Evaluating Disseminated Effects of Incomplete Data in Network-Based Studies for Public Health
Author(s): TingFang Lee* and Ashley Buchanan and Natallia Katenka and M. Elizabeth Halloran and Samuel Friedman and Georgios Nikolopoulos
Companies: College of Pharmacy, University of Rhode Island and College of Pharmacy, University of Rhode Island and Department of Computer Science and Statistics, University of Rhode Island and Public Health Sciences Division, Fred Hutch and Department of Population Health, NYU Grossman School of Medicine and Medical School, University of Cyprus
Keywords: Causal inference; Missing data; Network Studies; People who Use Drugs; HIV/AIDS

Estimating causal effects in the presence of interference among individuals embedded within a social network is often challenged by missing information. The disseminated effect is the effect among the unexposed participants who are part of a network with those who received an intervention. In these network-based studies, outcomes may be missing due to the administrative end of the study or participants being lost to follow-up, also known as censoring. We extend an inverse probability weighted (IPW) estimator for network-based observational studies, where the interference sets are defined to be each participant's nearest neighbors, to consider when the outcome is subject to right censoring. Specifically, we use the inverse probability censoring weights (IPCW) to quantify the disseminated effects in a network-based study. A simulation study was conducted to evaluate the performance of the IPCW estimators. We employed the method to evaluate the disseminated effects of community alerts on self-reported HIV risk behavior among people who inject drugs and their risk contacts in the Transmission Reduction Intervention Project (TRIP), 2013 to 2015, Athens, Greece.

Authors who are presenting talks have a * after their name.

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