R2rtf - A Lightweight R Package to Produce Submission-Ready Tables and Figures in RTF Format

• Activity Number: 282 - Tools to Enable the Use of R by the Biopharmaceutical Industry in a Regulatory Setting
• Type: Topic-Contributed
• Date/Time: Wednesday, August 11, 2021 : 1:30 PM to 3:20 PM
• Sponsor: Biopharmaceutical Section
• Author(s): Yilong Zhang* and Siruo Wang and Simiao Ye and Madhusudhan Ginnaram and Keaven M Andersen
• Companies: Merck & Co., Inc. and John Hopkins University and Merck & Co., Inc. and Merck & Co., Inc. and Merck & Co. Inc.
• Keywords: clinical trials; R; RTF

Abstract

The use of open-source R is evolving in drug discovery, research and development for study design, data analysis, visualization, and report generation in the pharmaceutical industry. The ability to produce tables, listings and figures (TLFs) in customized rich text format (RTF) using R is crucial to enhance the workflow of using Microsoft Word to assemble analysis results. We developed an R package, r2rtf, that standardizes the approach to generate highly customized TLFs in RTF format. Code examples are provided to create customized RTF tables and figures with highlighted features. Based on the TLFs generated by r2rtf package, we further discuss a proposed process to submit the works to regulatory agency. The open-source r2rtf R package is available at: https://github.com/Merck/r2rtf.