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CC = Colorado Convention Center   H = Hyatt Regency Denver at Colorado Convention Center
* = applied session       ! = JSM meeting theme

Activity Details

343 Tue, 7/30/2019, 10:30 AM - 12:20 PM CC-111
Innovative Trial Designs and Analytics — Contributed Papers
Biopharmaceutical Section
Chair(s): Darcy Hille, Merck & Company Inc
10:35 AM On the Robustification of MAP Prior in Bayesian Historical Data Borrowing
Hongtao Zhang, AbbVie Inc.
10:50 AM Optimal Two-Stage Designs for Exploratory Basket Trials

Heng Zhou, Merck & Co., Inc; Fang Liu, Merck; Cai (Iris) Wu, Merck & Co., Inc; Cong Chen, Merck & Co., Inc
11:05 AM A Case Study of a Complex Design for a Clinical Trial with Features of Randomized Withdrawal and Parallel Randomization in a Rare Disease Area
Junxiang Luo, Sanofi-Aventis; Qi Zhang, Sanofi; Hui Quan, Sanofi US
11:20 AM A Bayesian Design with Conditional Borrowing of Historical Data in a Rare Disease Setting

Peng Sun; Ming-Hui Chen, University of Connecticut; Yiwei Zhang, Biogen; John Zhong, Biogen; Charlie Cao, Biogen; Guochen Song, Biogen; Zhenxun Wang, University of Minnesota,
11:35 AM Evaluation of False Discovery Rate in Platform Studies
Qiusheng Chen, Merck; Xiaoyun (Nicole) Li, Merck; Cong Chen, Merck & Co., Inc
11:50 AM Platform Trial Design with Incorporating Historical Data Dynamically
Weichao Bao, GlaxoSmithKline; Ohad Amit, GlaxoSmithKline; Sofia Paul, GlaxoSmithKline; Teri Ashton, GlaxoSmithKline; Karrie Wang, GlaxoSmithKline; Leah Suttner, GlaxoSmithKline
12:05 PM Adjustment of Subgroups Reversal Effect via Bayesian Borrowing Approach in Oncology Regulatory Submission
Rachael Liu, Takeda Pharmaceuticals ; Jianchang Lin, Takeda Pharmaceuticals; Veronica Bunn, Takeda Pharmaceuticals