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CC = Vancouver Convention Centre   F = Fairmont Waterfront Vancouver
* = applied session       ! = JSM meeting theme

Activity Details

617 * ! Thu, 8/2/2018, 8:30 AM - 10:20 AM CC-West 214
Indirect Comparisons of Treatment Effects for Clinical Regulatory and Health Economic Evaluations — Topic Contributed Papers
Biopharmaceutical Section
Organizer(s): Yanyan Zhu, Takeda Pharmaceuticals
Chair(s): James Signorovitch, Analysis Group
8:35 AM Retrospective Matched-Pairs Analysis for Clinical Trial Patient Level Data: a Simulation Study and General Considerations
Bingxia Wang, Takeda Pharmaceuticals Inc.; Chenchen Ma; Yanyan Zhu, Takeda Pharmaceuticals; Guohui Liu, Takeda Pharmaceuticals Inc
8:55 AM Inference for Clinical Trials That Rely on Historical Data: a Review of Statistical Approaches for Reducing Risk of Bias

Lei Nie, Division of Biometrics V, office of Biostatistics, CDER/FDA; James Signorovitch, Analysis Group; Rajeev Ayyagari, Analysis Group
9:15 AM An Overview of Matching Adjusted Indirect Comparisons in Single Arm Clinical Trials with Practical Recommendations and Potential Challenges

Dawn Odom, RTI Health Solutions; Molly Purser, RTI Health Solutions; Lawrence Rasouliyan, RTI Health Solutions
9:35 AM Matching Adjusted Indirect Comparisons: Sensitivity Analyzes and Graphical Diagnostics

Wei Gao, Analysis Group, Inc.; Vanya Rybkin, Analysis Group, Inc.; Zhiwen Yao, Analysis Group, Inc.; Michael Hellstern, Analysis Group, Inc.; James Signorovitch, Analysis Group
9:55 AM Uncontrolled Studies and Health Technology Appraisal ? The Need for Methods, Modeling, and Further Research

Anthony Hatswell, University College London
10:15 AM Floor Discussion