Abstract:
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Ng and Hshieh (2016) proposed graphical approaches using scatter plot, Bland-Altman plot and Q-Q plot to assess (i) individual bioequivalence of a generic drug and (ii) interchangeability of a proposed biosimilar product to a reference product. In this paper, concordance correlation coefficient (Lin, 1989) is used instead of the plots. Simulated and real data are used to illustrate the new method.
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