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178 Mon, 8/5/2013, 10:30 AM - 12:20 PM CC-512ab
Bayesian Methods in Early-Phase Clinical Trials — Contributed Papers
Biopharmaceutical Section , International Society for Bayesian Analysis (ISBA) , International Chinese Statistical Association , Biometrics Section
Chair(s): John Scott, Center for Biologics Evaluation and Research/FDA
10:35 AM Bayesian PPOS Design for Pilot Drug Development Zhongwen Tang, Novartis Oncology ; Jyotirmoy Dey, Novartis Oncology
10:50 AM A Two-Stage Bayesian Design with Sample-Size Re-Estimation and Subgroup Analysis for Phase II Binary Response Trials Wei Zhong, Genentech Inc. ; Joseph S. Koopmeiners, University of Minnesota ; Bradley P. Carlin, University of Minnesota
11:05 AM A Novel Bayesian Approach to Designing Dose-Ranging Clinical Trials: A More Efficient Alternative to Traditional Approaches Jianjun Gan, GlaxoSmithKline ; Amy Cutrell, GlaxoSmithKline
11:20 AM Bayesian Adaptive Design in a Dose-Finding Study Zijiang Yang, Merck
11:35 AM Dose-Finding Using Bayesian E-Max Model to Find Minimum Effective Dose Yukiko Imai, GlaxoSmithKline
11:50 AM A Bayesian Design for Phase II Clinical Trials with Delayed Responses Based on Multiple Imputation Chunyan Cai, UT Health Science Center at Houston ; Suyu Liu, UT MD Anderson Cancer Center
12:05 PM Bayesian Dose-Finding for Combined Drugs with Discrete and Continuous Doses Lin Huo, Novartis Oncology ; Ying Yuan, UT MD Anderson Cancer Center ; Guosheng Yin, University of Hong Kong



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