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619 * Thu, 8/2/2012, 8:30 AM - 10:20 PM CC-Room 23B
Methodologies Related to Dose Response/Dose Finding — Contributed Papers
Biopharmaceutical Section
Chair(s): James Jiao, Janssen Pharmaceuticals R&D
8:35 AM A Dose-Finding Design with Time-to-Toxicity Endpoint Rui Qin, Mayo Clinic ; Xian-Jin Xie, The University of Texas Southwestern Medical Center at Dallas
8:50 AM Interim Pharmacokinetic Assessment Using a Bayesian Decision Analysis in Phase II Clinical Trials Bo Jin, Pfizer Inc. ; Keying Ye, The University of Texas at San Antonio
9:05 AM Preliminary Assessment of MCPMod for Dose-Response Modeling James Reynolds ; Joseph Gao, Shire Development Inc.
9:20 AM Use of Order-Restricted Simultaneous Inferences in Clinical Dose Study Data Analysis Gang Jia, Merck Research Laboratories
9:35 AM Biological Optimum Dose-Finding Trials for Cancer Targeted Agents Hao Liu, Baylor College of Medicine
9:50 AM Analysis of High-Throughput Screening (HTS) Assay Data Based on Preliminary Test Inference Changwon Lim, Loyola University Chicago ; Pranab K. Sen, The University of North Carolina at Chapel Hill ; Shyamal Peddada, National Institute of Environmental Health Sciences
10:05 AM Classification of Dose-Response Curves in Cell-Based In Vitro Assay for Toxicity Evaluation of Heterogeneous Compounds Donghui Zhang, Sanofi U.S. Inc. ; Chunpeng Fan, Sanofi U.S. Inc.



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