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405 * Tue, 7/31/2012, 2:00 PM - 3:50 PM CC-Room 27A
Advances in Design and Analysis of Clinical Trials — Contributed Papers
Biopharmaceutical Section
Chair(s): Xiaoping Jiang, FDA/CDER/OTS/OB
2:05 PM Elemental Information Matrices in Optimal Design of Experiments Valerii Fedorov, Quintiles, Inc.
2:20 PM Minimal Plus One Point Designs for Testing Lack of Fit for Some Sigmoid Curve Models Ying Su, Merck ; Damaraju Raghavarao, Temple University
2:35 PM Isotonic Regression for Estimating the Highest Impedance Time Point for Deep Brain Stimulation Yufan Zhao, Boston Scientific Neuromodulation ; Lilly Chen, Boston Scientific Neuromodulation ; Nitzan Mekel-Bobrov, Boston Scientific Neuromodulation
2:50 PM Minimal Plus One Design Points for Some Mixture Models Yanyan Li, Teva Branded Pharmaceutical Products R&D, Inc. ; Damaraju Raghavarao, Temple University
3:05 PM Bayesian Two-Stage Sequential Design for Phase II Clinical Trials Sumihiro Suzuki, University of North Texas Health Science Center ; Jun Zhang, University of North Texas Health Science Center ; Shande Chen, University of North Texas Health Science Center
3:20 PM Hypothesis Testing and Estimation in Ordinal Data Under a Simple Crossover Design Kung-Jong Lui, San Diego State University ; Kuang-Chao Chao, Fu-Jen Catholic University
3:35 PM A Patient Recruitment Mixed Distribution Model with Center Initiation Cycle Times James Powers, Quintiles, Inc.



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