This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.

Activity Details

238 Mon, 8/2/2010, 2:00 PM - 3:50 PM CC-302/303 (West)
Biomarkers — Contributed Papers
Biopharmaceutical Section
Chair(s): Neal Thomas, Pfizer Inc.
2:05 PM Evaluating Correlation and Some Misuses for Biomarker Qualification Within a Causal Correlation Framework Yue Wang, Merck & Co., Inc. ; Robin Mogg, Merck & Co., Inc. ; Peter H. Hu, Merck & Co., Inc. ; Jared Lunceford, Merck & Co., Inc. ; Peggy Wong, Merck Research Laboratories
2:20 PM Detecting a Cutoff Point for Predictive Biomarkers in Clinical Trials Using Contrast Tests Jianliang Zhang, MedImmune
2:35 PM Using Logistic Model with Measurement Errors in Covariates to Assess Baseline Biomarkers Association with Treatment Response Dion Chen, Centocor R&D, Inc. ; Jiandong Lu, Johnson & Johnson
2:50 PM An Orthogonal Transformed Aggregation Statistic to Test Gene Regulation with Prespecified Gene Sets or Pathways Shuyan (Sabrina) Wan, Merck Research Laboratories ; Nanshi Sha, Columbia University ; Peggy Wong, Merck Research Laboratories
3:05 PM Use of Receiver Operating Characteristic (ROC) Curves to Evaluate High-Throughput Screening (HTS) Methodologies Satya R. Siddani, Merck & Co., Inc.
3:20 PM Issues on Threshold Selection in Predictive Biomarker Analysis Li-an Xu, Bristol-Myers Squibb
3:35 PM Dimension Reduction Through Variable Selection: A Fibrosis Case Study Katja Sabine Remlinger, GlaxoSmithKline

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