JSM 2004 - Toronto

Abstract #300096

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Activity Number: 66
Type: Invited
Date/Time: Monday, August 9, 2004 : 8:30 AM to 10:20 AM
Sponsor: Section on Risk Analysis
Abstract - #300096
Title: Modeling the Risks of Emerging Threats to the Blood Supply
Author(s): Susie ElSaadany*+
Companies: Health Canada
Address: Population and Public Health Branch, Statistics and Risk Assessment Section, Ottawa, ON, K1A OL2, Canada
Keywords: mathematical modeling ; West Nile Virus ; public health ; infectious disease ; transmissible spongiform encephalopathies
Abstract:

Mathematical modeling is increasingly being used to identify useful interventions to reduce risks to the blood supply from emerging threats. Among those threats is the West Nile Virus. In 2002 several cases of West Nile Virus may have been transmitted via blood and blood products, categorizing the agent as a threat to the safety of the blood supply. Transmissible Spongiform Encephalopathies (TSEs) such as Creutzfeldt Jakob Disease (CJD) and variant Creutzfeldt Jakob Disease (vCJD) may similarly pose risks of transmission through blood products, although TSE transmission to humans via blood transfusion has not been observed. Progress on modeling the potential risks arising from these new emerging infectious agents and the effectiveness of current interventions, such as the blood donor questionnaire, will be presented. Examples will highlight the applications of modeling to addressing emerging infectious disease agents and the difficulty of modeling when data are limited and the resulting uncertainty high.


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