Abstract #301891

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JSM 2003 Abstract #301891
Activity Number: 461
Type: Invited
Date/Time: Thursday, August 7, 2003 : 10:30 AM to 12:20 PM
Sponsor: ENAR
Abstract - #301891
Title: Randomization Inference in Covariance Adjustment in a Randomized Controlled Trial with Incomplete Longitudinal Data
Author(s): Robert A. Greevy*+
Companies: The Wharton School, University of Pennsylvania
Address: 3730 Walnut St., Philadelphia, PA, 19104-6340,
Keywords:
Abstract:

A recent proposal for randomization inference in covariance adjustment offers the option to control for baseline imbalances with various regression methods while preserving the framework of a randomization test. Applied to a randomized controlled trial, narrower confidence intervals are achieved through adjusting for baseline differences. The method will be illustrated in a clinical trial of treatments following childhood cancer, with incomplete longitudinal data from a thick-tailed multivariate distribution.


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