Online Program Home
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All Times EDT
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* = applied session ! = JSM meeting theme
Activity Details
2 !
Sun, 8/8/2021,
1:30 PM -
3:20 PM
Virtual
When Causal Inference Meets Reinforcement Learning: The Story of Mobile-Delivered Interventions — Invited Papers
IMS , ENAR, Biometrics Section
Organizer(s): Min Qian, Columbia University
Chair(s): Chengchun Shi, LSE
1:35 PM
Assessing Time-Varying Causal Effects in the Presence of Cluster-Level Treatment Effect Heterogeneity
Jieru Hera Shi, University of Michigan, Ann Arbor; Zhenke Wu, University of Michigan, Ann Arbor ; Walter Dempsey, University of Michigan
2:00 PM
Policy Evaluation Under Interference
Stefan Wager, Stanford University
2:25 PM
We Used RL, but … Did It Work?!
Peng Liao, Harvard University ; Susan Murphy, Harvard University; Predrag Klasnja, University of Michigan
2:50 PM
Discussant: Michael Kosorok, University of North Carolina at Chapel Hill
3:10 PM
Floor Discussion
4 * !
Sun, 8/8/2021,
1:30 PM -
3:20 PM
Virtual
Theoretical and Empirical Contributions to Data Analytic Practice — Invited Papers
ENAR , Ad Hoc Statistical Leadership Training Committee, Business Analytics/Statistics Education Interest Group, Caucus for Women in Statistics
Organizer(s): Roger Peng, Johns Hopkins University
Chair(s): Jeffrey Leek, Johns Hopkins Bloomberg School of Public Health
1:35 PM
Evaluating the Alignment of a Data Analysis Between Analyst and Audience
Stephanie C Hicks, Johns Hopkins Bloomberg School of Public Health ; Roger Peng, Johns Hopkins University
2:00 PM
How Data Scientists Navigate the Outer Loop of Client Collaborations in Industry and Academia
Sean Kross, The University of California San Diego
2:25 PM
Examining the Impact of Software Instruction on Completion of Data Analysis Tasks
Lucy D'Agostino McGowan, Wake Forest University
2:50 PM
Discussant: Roger Peng, Johns Hopkins University
3:10 PM
Floor Discussion
5 * !
Sun, 8/8/2021,
1:30 PM -
3:20 PM
Virtual
Novel Methods for Microbiome Data Analysis — Invited Papers
Section on Statistics in Genomics and Genetics , Biometrics Section, ENAR
Organizer(s): Shulei Wang, University of Illinois at Urbana-Champaign
Chair(s): Shulei Wang, University of Illinois at Urbana-Champaign
1:35 PM
Deep Learning to Predict the Biosynthetic Gene Clusters in Bacterial Genomes
Hongzhe Li, University of Pennsylvania
2:00 PM
Kernel Methods for Identifying of Genetic Variants Associated with Microbiome Composition
Michael C Wu, Fred Hutchinson Cancer Research Center
2:25 PM
Model-Based Approaches to Dimension Reduction, Unconstrained Ordination, and Composition Estimation for Microbiome Data
Tao Wang, Shanghai Jiao Tong University
2:50 PM
Correcting Measurement Error in High-Throughput Sequencing Data
David Clausen, University of Washington
3:15 PM
Floor Discussion
13 *
Sun, 8/8/2021,
1:30 PM -
3:20 PM
Virtual
Advances in Longitudinal Methods in Research on Aging and Dementia from the MEthods for LOngitudinal Studies of DEMentia (MELODEM) Initiative — Invited Papers
Biometrics Section , Lifetime Data Science Section, ENAR
Organizer(s): Michelle Shardell, University of Maryland School of Medicine
Chair(s): Michelle Shardell, University of Maryland School of Medicine
1:35 PM
Prediction of Dementia Types Using Machine Learning Methods
Chung-Chou H. Chang, University of Pittsburgh; Yueting Wang, University of Pittsburgh ; Yichen Jia, University of Pittsburgh; Mary Ganguli, University of Pittsburgh
1:55 PM
Causal Mediation Analysis of the Timing of Risk Factors for Incident Cognitive Impairment
Nicole Armstrong, Alpert Medical School of Brown University
2:15 PM
Joint Modeling of the Temporal Relationships Between Multivariate Longitudinal Markers of Alzheimer’s Disease Progression and Clinical Endpoints
Anaïs Rouanet, Inserm U1219 - Bordeaux Population Health research center ; Cécile Proust-Lima, University of Bordeaux
2:35 PM
Estimating Heterogenous Effects of Education on Dementia Using Bayesian Trees
Jordan Weiss, University of California, Berkeley ; Sameer Deshpande, Massachusetts Institute of Technology - CSAIL
2:55 PM
Using Hidden Markov Models to Track Cognitive Decline
Presentation
Terry Michael Therneau, Mayo Clinic
3:20 PM
Discussant: Cécile Proust-Lima, University of Bordeaux
3:15 PM
Floor Discussion
15 * !
Sun, 8/8/2021,
1:30 PM -
3:20 PM
Virtual
Emerging Statistical Challenges and Opportunities in Mental Health Research — Invited Panel
Mental Health Statistics Section , Biometrics Section, ENAR, Caucus for Women in Statistics
Organizer(s): Adam Ciarleglio, George Washington University
Chair(s): Adam Ciarleglio, George Washington University
1:35 PM
Emerging Statistical Challenges and Opportunities in Mental Health Research
Panelists:
Melanie Wall, Columbia University
Eva Petkova, New York University School of Medicine
Garrett Fitzmaurice, Harvard University
Susan Shortreed, Kaiser Permanente Washington Health Research Institute
3:15 PM
Floor Discussion
33
Sun, 8/8/2021,
3:30 PM -
5:20 PM
Virtual
Sensitivity Analysis with Nonignorable Missing Data: Recent Work from Academia, Industry, and Regulatory Agencies — Invited Papers
ENAR , IMS, Society for Clinical Trials
Organizer(s): Shu Yang, North Carolina State University
Chair(s): Shu Yang, North Carolina State University
3:35 PM
Sensitivity Analysis Applications in Some Regulatory Experience
Eiji Ishida, FDA
4:00 PM
Control-Based Imputation in Longitudinal Clinical Trials for Continuous Outcomes with Outliers
G. Frank Liu, Merck Sharp & Dohme Corp. ; Yilong Zhang, Merck & Co., Inc.; Gregory Golm, Merck & Co., Inc.
4:25 PM
Global Sensitivity Analysis of Randomized Trials with Non-Monotone Missing Binary Outcomes: Application to Studies of Substance Use Disorders
Daniel Scharfstein, University of Utah
4:50 PM
Discussant: Roderick Joseph Little, University of Michigan
5:10 PM
Floor Discussion
43 * !
Sun, 8/8/2021,
3:30 PM -
5:20 PM
Virtual
Distributed Regressions in Real-World Data — Invited Papers
Section on Statistics in Epidemiology , ENAR, Section for Statistical Programmers and Analysts
Organizer(s): Yong Chen, University of Pennsylvania
Chair(s): Jiayi Tong, University of Pennsylvania
3:35 PM
Distributed Privacy-Preserving Estimation of Time-to-Event Models
Chao-Kang Jason Liang, National Institute of Allergy and Infectious Diseases
4:00 PM
Combining Cox Regressions Across a Heterogeneous Distributed Research Network Facing Small and Zero Counts
Martijn Schuemie, Janssen R&D
4:25 PM
Statistical Inferences with Distributed Estimators
Cheng Yong Tang, Temple University
4:50 PM
Distributed Regression: Estimation, Prediction, and Inference
Yong Chen, University of Pennsylvania
5:15 PM
Floor Discussion
62 * !
Mon, 8/9/2021,
10:00 AM -
11:50 AM
Virtual
Large Population Physical Activity Studies Using Wearable Devices: Challenges and Future Directions — Invited Papers
Section on Statistics in Epidemiology , ENAR, Biometrics Section
Organizer(s): Ekaterina Smirnova, Virginia Commonwealth University
Chair(s): Ekaterina Smirnova, Virginia Commonwealth University
10:05 AM
Unraveling the Relationship Between Physical Activity and Health Using Wearable Sensors
Charles Matthews, National Cancer Institute Shady Grove
10:25 AM
Fast Univariate Inference for Longitudinal Functional Models
Erjia Cui, Johns Hopkins Bloomberg School of Public Health ; Andrew Leroux, University of Colorado Anschutz Medical Campus; Ciprian Crainiceanu, Johns Hopkins University; Ekaterina Smirnova, Virginia Commonwealth University
10:45 AM
The Digital Biomarker Discovery Project: An Open Source Toolbox Biosignal Analysis
Jessilyn Dunn, Duke University ; Brinnae P Bent, Duke University; Emilia Grzesiak, Duke University; Chentian Jiang, Duke University; Yuankai P Qi, Duke University; Yihang P Jiang, Duke University; Peter P Cho, Duke University
11:05 AM
Genome-Wide Association Studies of 27 Accelerometry-Derived Physical Activity Measurements Identifies 6 Novel Loci and Links with Blood and Immune Mechanisms
Guanghao Qi, Johns Hopkins University ; Diptavo Dutta, Johns Hopkins University; Andrew Leroux, University of Colorado Anschutz Medical Campus; Debashree Ray, Johns Hopkins University; Ciprian Crainiceanu, Johns Hopkins University; Nilanjan Chatterjee, Johns Hopkins University
11:25 AM
New Methodology for Characterizing Circadian Rhythm in Actigraphy Data Collected from a Wearable Device
Sungduk Kim, National Cancer Institute ; Paul S. Albert, National Cancer Institute
11:45 AM
Floor Discussion
68 !
Mon, 8/9/2021,
10:00 AM -
11:50 AM
Virtual
Recent Advances of Causal Inferences in Human Genetics — Invited Papers
WNAR , Section on Statistics in Genomics and Genetics, ENAR
Organizer(s): Jingshen Wang, UC Berkeley; Chong Wu, Florida State University
Chair(s): Chong Wu, Florida State University
10:05 AM
Inferring Causal Direction Between Two Traits in the Presence of Invalid Instrumental Variables
Haoran Xue, University of Minnesota ; Wei Pan, University of Minnesota
10:30 AM
Testing for the Direction of Mediation in Genomics Studies
James Dai, Fred Hutchinson Cancer Research Center ; Heng Chen, Fred Hutchinson Cancer Research Center
10:55 AM
Debiased Inference in Mendelian Randomization After Selecting Among High-Dimensional Genetic Instruments
Chong Wu, Florida State University; Jingshen Wang, UC Berkeley
11:20 AM
KnockoffScreen: A Powerful Method for the Identification of Putative Causal Loci in Whole-Genome Sequencing Data via Knockoff Statistics
Iuliana Ionita-Laza, Columbia University; Zihuai He, Stanford University
11:45 AM
Floor Discussion
70 * !
Mon, 8/9/2021,
10:00 AM -
11:50 AM
Virtual
Statistical Advances for Multi-Omics Data of Complex Diseases — Invited Papers
Section on Statistics in Genomics and Genetics , ENAR, Biometrics Section, Caucus for Women in Statistics
Organizer(s): Jiebiao Wang, University of Pittsburgh
Chair(s): Jiebiao Wang, University of Pittsburgh
10:05 AM
SpotClean adjusts for spot swapping in spatial transcriptomics data
Christina Kendziorski, UW-Madison ; Zijian Ni, UW-Madison; Jared Brown, UW-Madison; Chitrasen Mohanty, UW-Madison
10:30 AM
Multi-Omics Analysis of Psychosis in Alzheimer’s Disease
Ying Ding, University of Pittsburgh
10:55 AM
Integrating GWAS and multi-omics QTL summary statistics to elucidate disease genetic mechanisms via a hierarchical low-rank model
Lin Chen, University of Chicago ; Yihao Lu, University of Chicago
11:20 AM
Integrative Single Cell Analysis of DNA Alterations and Chromatin Accessibility in Cancer
Chi-Yun Wu, University of Pennsylvania; Nancy Zhang, The University of Pennsylvania ; Hanlee Ji, Stanford University
11:45 AM
Floor Discussion
82 * !
Mon, 8/9/2021,
10:00 AM -
11:50 AM
Virtual
Evaluating Causal Effects Using Incomplete Data with Interference in Public Health Research — Topic-Contributed Papers
ENAR , Section on Statistics in Epidemiology, Biopharmaceutical Section
Organizer(s): TingFang Lee, College of Pharmacy, University of Rhode Island
Chair(s): Ashley Buchanan, College of Pharmacy, University of Rhode Island
10:05 AM
Causal Effects with Hidden Treatment Diffusion Over Partially Unobserved Networks
Costanza Tortù, Ecole Polytechnique ; Irene Crimaldi, IMT Lucca; Fabrizia Mealli, University of Florence; Laura Forastiere, Yale University
10:25 AM
Doubly Robust Treatment Effect Estimation with Missing Attributes
Imke Mayer, Centre d'Analyse et de Mathématiques Sociales, EHESS ; Erik Sverdrup, Graduate School of Business, Stanford University; Tobias Gauss, Department of Anesthesia and Intensive Care, Beaujon Hospital, AP-HP; Jean-Denis Moyer, Department of Anesthesia and Intensive Care, Beaujon Hospital, AP-HP; Stefan Wager, Stanford University; Julie Josse, INRIA Sophia-Antipolis
10:45 AM
Evaluating Disseminated Effects of Incomplete Data in Network-Based Studies for Public Health
Presentation
TingFang Lee, College of Pharmacy, University of Rhode Island ; Ashley Buchanan, College of Pharmacy, University of Rhode Island; Natallia Katenka, Department of Computer Science and Statistics, University of Rhode Island; M. Elizabeth Halloran, Public Health Sciences Division, Fred Hutch; Samuel Friedman, Department of Population Health, NYU Grossman School of Medicine; Georgios Nikolopoulos, Medical School, University of Cyprus
11:05 AM
Leveraging Influencers in the Design of Network-Structured Studies to Estimate Direct and Spillover Effects
Junhan Fang, Yale School of Public Health ; Donna Spiegelman, Yale School of Public Health; Laura Forastiere, Yale University
11:25 AM
Discussant: Samrachana Adhikari, NYU School of Medicine
11:45 AM
Floor Discussion
91
Mon, 8/9/2021,
10:00 AM -
11:50 AM
Virtual
High Dimensional Data, Causal Inference, Biostats Education, and More — Contributed Speed
ENAR
Chair(s): Wodan Ling, Fred Hutchinson Cancer Research Center
10:05 AM
Bayesian Nonparametric Models for Freely Diffusing SmFRET Data
Roberto Rivera, University of Puerto Rico at Mayaguez ; Jared Hidalgo, University of Puerto Rico - Mayaguez; Axel Cortes Cubero, University of Puerto Rico at Mayaguez; Roberto Reyes, University of Puerto Rico at Mayaguez
10:10 AM
Principal Component Analysis of Hybrid Functional and Vector Data
Jeong Hoon Jang, Indiana University
10:15 AM
A P-Value-Free FDR Controlling Approach for High-Dimensional Variable Selection
Arkaprabha Ganguli, Michigan State University ; David Todem, Michigan State University
10:20 AM
Multisite Learning with High-Dimensional Data via a Distributed Algorithm for Penalized Regression (ADAP)
Xiaokang Liu, University of Pennsylvania ; Rui Duan, Harvard University; Chongliang Luo, University of Pennsylvania; Alexis Ogdie, University of Pennsylvania ; Jason H. Moore, University of Pennsylvania ; Henry R. Kranzler, University of Pennsylvania ; Jiang Bian, University of Florida Health Cancer Center; Yong Chen, University of Pennsylvania
10:25 AM
Prediction of Relapse in Chronic Disease Using Fragmented Medical Records
Jiasheng Shi, University of Pennsylvania Perelman School of Medicine ; Jing Huang, University of Pennsylvania Perelman School of Medicine
10:30 AM
Relaxed Conditional Likelihood for Sparse Data Under a Rectangular Array Embedding
Samuel Aiyedipe, Department of Biostatistics and Bioinformatics, Emory University ; John Hanfelt, Emory University
10:35 AM
Three-Phase Generalized Raking and Multiple Imputation Estimators to Address Errors in Routinely Collected Data
Gustavo Amorim, Vanderbilt University Medical Center ; Ran Tao, Vanderbilt University Medical Center; Sarah Lotspeich, Vanderbilt University Medical Center; Pamela Shaw, Kaiser Permanente Washington Health Research Institute; Thomas Lumley, University of Auckland; Rena Patel, University of Washington; Bryan Shepherd, Department of Biostatistics, Vanderbilt University School of Medicine
10:40 AM
Tests for Heteroscedasticity
Timothy Mark Beasley, UAB
10:45 AM
Lossless Distributed Linear Mixed Model with Application to Integration of Heterogeneous Health Care Data
Chongliang Luo, University of Pennsylvania ; Md. Nazmul Islam, UnitedHealth Group; Natalie E. Sheils, UnitedHealth Group; Rui Duan, Harvard University; Jenna Reps, Janssen Research and Development LLC; Jiayi Tong, University of Pennsylvania; Mackenzie Edmonson, University of Pennsylvania; Martijn Schuemie, Janssen R&D; John Buresh, UnitedHealth Group; Yong Chen, University of Pennsylvania
10:50 AM
A Job-Ready Assessment for Post-Graduate-Level Introductory Biostatistics Courses
Darsy Darssan, The University of Queensland ; Pakhi Sharma, The University of Queensland; Alexandra Robbins-Hill, The University of Queensland; Gail Williams, The University of Queensland
11:00 AM
Information-Based Mediation Analysis on High-Dimensional Metagenomic Data
Lingling An, University of Arizona ; Kyle Carter, University of Arizona; Meng Lu, University of Arizona; Hongmei Jiang, Northwestern University
11:05 AM
Increasing efficiency and reducing bias of vaccine effect estimates, by using non-targeted virus strains
Lola Etievant, National Cancer Institute, NIH ; Mitchell Gail, NCI-DCEG; Joshua Sampson, National Cancer Institute, NIH
11:10 AM
When Randomized Interventional Indirect Effects Tell Stories About Mediated Effects (and When They Don’t)
Presentation
Caleb Miles, Columbia University
11:15 AM
Comparison of Propensity Score Weighting Methods for Subgroup Survival Analysis
Siyun Yang, Duke University ; Fan Li, Duke University; Laine Thomas, Duke University, Department of Biostatistics and Bioinformatics
11:20 AM
Optimal Weighting for Estimating Generalized Average Treatment Effects
Michele Santacatterina, George Washington University ; Nathan Kallus, Cornell University
11:25 AM
Laplace and Saddlepoint Approximations in High Dimensions
Yanbo Tang, University of Toronto ; Nancy Reid, University of Toronto
11:30 AM
Randomization Tests to Address Disruptions in Clinical Trials
Diane Uschner, George Washington University
11:35 AM
Mathematical Modeling of the Transmission Dynamics of COVID-19
Ruzong Fan, Georgetown University Medical Center (GUMC)
11:40 AM
Statistical Challenges of Launching a Randomized Controlled Trial of a COVID-19 Therapeutic at the Start of the Pandemic
Pamela Shaw, Kaiser Permanente Washington Health Research Institute ; Grace Choi, University of Pennsylvania; Haidaliza Soto-Calderon, University of Pennsylvania; Lizette Grajales, University of Pennsylvania; Katharine Bar, University of Pennsylvania
11:45 AM
Updating an Introductory Biostatistics Course to Support Diversity, Equity, Inclusion, and Transparency
Priya Srikanth, Oregon Health & Science University ; Amber Lin, Oregon Health & Science University
119 * !
Mon, 8/9/2021,
1:30 PM -
3:20 PM
Virtual
SciComm and Stats: Communicating Statistics to the Public in the New Decade — Invited Panel
ENAR , Committee on Membership Retention and Recruitment, Council of Emerging and New Statisticians (CENS), Caucus for Women in Statistics
Organizer(s): Jeong Hoon Jang, Indiana University; Sarah Samorodnitsky, University of Minnesota
Chair(s): Nicole Butera, George Washington University
1:35 PM
SciComm and Stats: Communicating Statistics to the Public in the New Decade
Panelists:
John Bailer, Miami University
Irineo Cabreros, RAND
Natalie Dean, University of Florida
Regina Nuzzo, American Statistical Association
Brian Tarran, Significance Magazine
Nick Thieme, Atlanta Journal-Constitution
3:15 PM
Floor Discussion
121 * !
Mon, 8/9/2021,
1:30 PM -
3:20 PM
Virtual
In the Pipeline: Statistical Advances to Preserve Biological Signal in High-Throughput, Single-Cell Imaging and Sequencing Methods — Topic-Contributed Papers
Section on Statistics in Imaging , Section on Statistics in Genomics and Genetics, ENAR
Organizer(s): Coleman R Harris, Vanderbilt University Medical Center
Chair(s): Simon N Vandekar, Vanderbilt University
1:35 PM
ComBat-Seq: Batch Effect Adjustment for RNA-Seq Count Data
W. Evan Johnson, Boston University School of Medicine ; Yuqing Zhang, Gilead Sciences, Inc.; Giovanni Parmigiani, Harvard University
1:55 PM
Comparison of Normalization Methods to Combine Batches of High-Dimensional Multiplexed Images
Presentation
Coleman R Harris, Vanderbilt University Medical Center ; Qi Liu, Vanderbilt University Medical Center; Eliot McKinley, Vanderbilt University Medical Center; Joseph Roland, Vanderbilt University Medical Center; Ken Lau, Vanderbilt University Medical Center; Robert Coffey, Vanderbilt University Medical Center; Simon N Vandekar, Vanderbilt University
2:15 PM
Design and Analysis of High-Throughput Cell Imaging Studies
Johann Gagnon-Bartsch, University of Michigan ; Gregory Hunt, College of William & Mary
2:35 PM
Robust Re-Scaling of Imaging Data to Improve Discovery of Latent Effects
Gregory Hunt, College of William & Mary ; Johann Gagnon-Bartsch, University of Michigan
2:55 PM
Back to the Future: Viewing Single-Cell Assays Through the Lens of Chromatin Structure
Timothy J. Triche, Van Andel Institute ; Benjamin K Johnson, Van Andel Institute; Hui J Shen, Van Andel Institute
3:15 PM
Floor Discussion
128 *
Mon, 8/9/2021,
1:30 PM -
3:20 PM
Virtual
New Methods and Diagnostics for Propensity Score Matching — Topic-Contributed Papers
Health Policy Statistics Section , Biometrics Section, ENAR
Organizer(s): Ben B. Hansen, University of Michigan
Chair(s): Ben B. Hansen, University of Michigan
1:35 PM
Evaluating and Improving a Matched Comparison of Antidepressants and Bone Density
Ruoqi Yu, University of Pennsylvania
1:55 PM
Accounting for Inexact Matching via Model-Weighted Randomization Inference and Partially Randomized Design
Samuel D. Pimentel, University of California, Berkeley
2:15 PM
Fast Algorithms for Propensity Score Matching
Presentation
Pavel Ruzankin, Novosibirsk State University ; Anton S. Tarasenko, Novosibirsk State University
2:35 PM
Full Matching with More Precise Set Size Constraints
Presentation
Mark Fredrickson, University of Michigan, Ann Arbor ; Ben B. Hansen, University of Michigan
2:55 PM
Discussant: Thomas E. Love, Case Western Reserve University School of Medicine
3:15 PM
Floor Discussion
139 * !
Tue, 8/10/2021,
10:00 AM -
11:50 AM
Virtual
Recent Advances of Semi-Supervised Learning: Techniques and Applications — Invited Papers
Section on Statistical Learning and Data Science , Section on Nonparametric Statistics, ENAR
Organizer(s): Jiwei Zhao, University of Wisconsin-Madison
Chair(s): Jiwei Zhao, University of Wisconsin-Madison
10:05 AM
Optimal Semi-Supervised Estimation and Inference for High-Dimensional Linear Regression
Yang Ning, Cornell University ; Jiwei Zhao, University of Wisconsin-Madison; Heping Zhang, Yale University
10:25 AM
Inference for Maximin Effects: A Sampling Approach to Aggregating Heterogenous High-Dimensional Regression Models
Zijian Guo, Rutgers University
10:45 AM
Semi-Supervised Off Policy Reinforcement Learning
Aaron Sonabend, Harvard University ; Tianxi Cai, Harvard T.H. Chan School of Public Health
11:05 AM
Doubly Robust Semi-Supervised Inference for Means Under MAR-Type Labeling Mechanisms with Selection Bias and Decaying Propensity Scores
Abhishek Chakrabortty, Texas A&M University
11:25 AM
Semi-Supervised Learning with Network Information
Linda Zhao, University of Pennsylvania; Junhui Cai, University of Pennsylvania ; Haipeng Shen, University of Hong Kong; Dan Yang, University of Hong Kong; Wu Zhu, University of Pennsylvania
11:45 AM
Floor Discussion
143 * !
Tue, 8/10/2021,
10:00 AM -
11:50 AM
Virtual
New Machine Learning Tools for Mobile Health Data and Individual Intervention — Invited Papers
Lifetime Data Science Section , Section on Statistical Learning and Data Science, IMS, ENAR
Organizer(s): Annie Qu, Unviersity of California Irvine
Chair(s): Bin Nan, University of California Irvine
10:05 AM
Inference of Causal Relations with Interventions
Chunlin Li, University of Minnesota; Xiaotong T Shen, University of Minnesota ; Wei Pan, University of Minnesota
10:30 AM
Tracking Weight Loss Before and During Pregnancy
Heping Zhang, Yale University
10:55 AM
Efficient Learning of Optimal Individualized Treatment Rules
Weibin Mo, University of North Carolina; Yufeng Liu, University of North Carolina at Chapel Hill
11:20 AM
Supervised Learning of Health-Related Secret Codes from Wearable Devices Data
Peter X.K. Song, University of Michigan
11:45 AM
Floor Discussion
144 * !
Tue, 8/10/2021,
10:00 AM -
11:50 AM
Virtual
Biases, Batch Effects, and Novel Statistical Methodologies: Handling Them in Large-Scale Microbiome Sequencing Studies — Invited Papers
ENAR , Biometrics Section, Canadian Statistical Sciences Institute
Organizer(s): Ni Zhao, Johns Hopkins University
Chair(s): Anna Plantinga, Williams College
10:05 AM
ConQuR: Batch Effect Correction for Microbiome Data via Conditional Quantile Regression
Wodan Ling, Fred Hutchinson Cancer Research Center ; Michael C Wu, Fred Hutchinson Cancer Research Center
10:25 AM
Bias-Robust Analysis of Microbiome Data
Glen Satten, Emory University
10:45 AM
Differential Abundance Analysis of Microbiomes with Bias Correction
Shyamal Peddada, The Eunice Kennedy Shriver National Institute of Child Health and Human Development
11:05 AM
BugSigDB: A Database of Published Microbial Signatures
Levi Waldron, CUNY Graduate school Public Health and Health Policy
11:25 AM
Integrative Analysis of Multiple Microbiome Data Sets: Robust Models Against Biases and Batches
Ni Zhao, Johns Hopkins University ; Mengyu He, JOHNS HOPKINS UNIVERSITY; Runzhe Li, Johns Hopkins Bloomberg School of Public Health
11:45 AM
Floor Discussion
149 * !
Tue, 8/10/2021,
10:00 AM -
11:50 AM
Virtual
Recent Advances in Statistical Methods for Microbiome Data — Invited Papers
International Indian Statistical Association , Section on Statistics in Genomics and Genetics, ENAR
Organizer(s): Subharup Guha, University of Florida
Chair(s): Subharup Guha, University of Florida
10:05 AM
Bioinformatics Pre-Processing of Microbiome Data with an Application to Metagenomic Forensics
SOMNATH DATTA, University of Florida; Samuel Anyaso-Samuel, University of Florida ; Archie Sachdeva, University of Florida; Subharup Guha, University of Florida
10:30 AM
Feature Selection for Microbiome Studies in the Presence of Confounding Using Standardization
Emily Goren, Iowa State University; Chong Wang, Iowa State University; Peng Liu, Iowa State University
10:55 AM
Dirichlet-Multinomial Regression Models with Bayesian Variable Selection for Microbiome Data
Marina Vannucci, Rice
11:20 AM
Generalized Matrix Decomposition for Exploration, Estimation, and Inference in Two-Way Structured Data
Timothy Randolph, Fred Hutch Cancer Research Center ; Ali Shojaie, University of Washington; Yue Wang, Arizona State University ; Jing Ma, Fred Hutchinson Cancer Research Center
11:45 AM
Floor Discussion
157 *
Tue, 8/10/2021,
10:00 AM -
11:50 AM
Virtual
Advances in Analytic Methods and Novel Applications of the Use of Synthetic Control for Causal Estimation of Effects of Therapeutic Interventions — Topic-Contributed Papers
Biometrics Section , ENAR, Section on Medical Devices and Diagnostics
Organizer(s): Margaret Gamalo, Pfizer
Chair(s): Chao-Kang Jason Liang, National Institute of Allergy and Infectious Diseases
10:05 AM
Synthetic Control Trial Design with Enhanced Double Robust Estimate of Rx Effect
Ming Tan, Georgetown University
10:25 AM
Evaluation of Diagnostic Tests for Low Prevalence Diseases with Leveraging Real-World Data
Wei-Chen Chen, FDA/CDRH ; Heng Li, FDA/CDRH; Nelson Lu, FDA/CDRH; Changhong Song, FDA/CDRH; Chenguang Wang, JHU; Ram Tiwari, FDA/CDRH; Yunling Xu, CDRH/FDA; Lilly Q. Yue, FDA/CDRH
10:45 AM
Innovative Adaptive Design for Confirmatory Trials: A Case Study in Pediatrics
Junjing Lin, Takeda Pharmaceuticals ; Margaret Gamalo-Siebers, Pfizer Inc.; Ran Liao, Eli Lilly
11:05 AM
Some Practical Issues of Augmenting Concurrent Control Data with Synthetic Control
Binbing Yu, AstraZeneca, LLC
11:25 AM
Design and Analysis of Externally Controlled Trials: Regulatory Review Experience in Hematology and Oncology Drug Applications
Presentation
Haiyan Chen, FDA
11:45 AM
Floor Discussion
158 * !
Tue, 8/10/2021,
10:00 AM -
11:50 AM
Virtual
Statistical Methods for High-Dimensional Data in Health Care and Medical Research — Topic-Contributed Papers
Section on Statistics in Epidemiology , International Society for Bayesian Analysis (ISBA), ENAR
Organizer(s): Zehang Richard Li, University of California, Santa Cruz
Chair(s): Zehang Richard Li, University of California, Santa Cruz
10:05 AM
Quantile Probit Copula Model for Association in Paired Study Data
Presentation
Roberta De Vito, Brown University ; Isabella Grabsky, Harvard University; Barbara Engelhardt, Princeton University
10:25 AM
Empirical Evaluation of Internal Validation Methods for Estimating Optimism Error in High-Dimensional Electronic Health Record Data with Rare Event Outcomes
Rebecca Yates Coley, Kaiser Permanente Washington Health Research Institute ; Qinqing Liao, University of Washington
10:45 AM
Validation of a Portable System for Molecular Diagnostics of SARS-CoV-2
Claudia Wehrhahn, University of California, Santa Cruz ; Maricarmen Quirasco Baruch, Universidad Nacional Autónoma de México; Luis Vaca Domínguez, Universidad Nacional Autónoma de México
11:05 AM
Bayesian Sparse Regression for Healthcare Analytics on Network of Observational Databases
Akihiko Nishimura, Johns Hopkins Bloomberg School of Public Health ; Marc Suchard, University of California Los Angeles
11:25 AM
Empirical Likelihood Approach for Variance Component Test with Repeated Accelerometry Measures
Haochang Shou, University of Pennsylvania
11:45 AM
Floor Discussion
161 * !
Tue, 8/10/2021,
10:00 AM -
11:50 AM
Virtual
Collaboratively Improve Trial Design and Result Interpretation Through the Estimand Framework — Topic-Contributed Panel
Biopharmaceutical Section , ENAR, Biometrics Section, Caucus for Women in Statistics
Organizer(s): Lei Nie, Office of Biostatistics (OB), OTS, CDER, FDA
Chair(s): Roderick Joseph Little, University of Michigan
10:05 AM
Collaboratively Improve Trial Design and Result Interpretation Through the Estimand Framework
Panelists:
Paul Kluetz, The US FDA
Gregory Levin, The US FDA
Bohdana Ratitch, Bayer
Anthony Man, Novartis
Sally Seymour, Food and Drug Administration
11:40 AM
Floor Discussion
183 * !
Tue, 8/10/2021,
1:30 PM -
3:20 PM
Virtual
Genomics in Neuroscience — Invited Papers
ENAR , Section on Statistics in Genomics and Genetics, Mental Health Statistics Section
Organizer(s): Wei Sun, Fred Hutchinson Cancer Research Center
Chair(s): Wei Sun, Fred Hutchinson Cancer Research Center
1:35 PM
Constructing Local Cell-Specific Networks from Single-Cell Data
Kathryn Roeder, CARNEGIE-MELLON UNIVERSITY ; Xuran Wang, CARNEGIE-MELLON UNIVERSITY; David Choi, Carnegie Mellon University
2:00 PM
Leveraging Gene Expression in Human Brain Tissue to Better Understand Schizophrenia and Its Genetic Risk
Andrew Jaffe, Johns Hopkins University
2:25 PM
Estimation of Gene-to-Trait Mediation via EQTL and GWAS Integration
Michael Love, UNC-Chapel Hill ; Anqi Zhu, UNC-Chapel Hill; Nana Matoba, UNC-Chapel Hill; Jason Stein, UNC-Chapel Hill; Emmaleigh Wilson, UNC-Chapel Hill; Amanda Tapia, UNC-Chapel Hill; Yun Li, UNC-Chapel Hill; Joseph G Ibrahim, UNC
2:50 PM
Deep Learning-Empowered Integrative Analysis of Single-Cell and Spatial Transcriptomics Data
Mingyao Li, University of Pennsylvania ; Jian Hu, University of Pennsylvania; Kyle Coleman, University of Pennsylvania; Amelia Schroeder, University of Pennsylvania
3:15 PM
Floor Discussion
187 * !
Tue, 8/10/2021,
1:30 PM -
3:20 PM
Virtual
Surrogate Markers and the Role of Mediation Analysis in Drug Development — Invited Papers
Biometrics Section , Lifetime Data Science Section, ENAR
Organizer(s): Peng Wei, The University of Texas MD Anderson Cancer Center
Chair(s): Peng Wei, The University of Texas MD Anderson Cancer Center
1:35 PM
Correlating Surrogate Endpoints with Overall Survival at the Individual Patient Level for Precision Oncology
Emily C Zabor, Cleveland Clinic
1:55 PM
Joint Modeling of Surrogate and Primary End Points via Causal Mediation Analyses
Yen-Tsung Huang, Academia Sinica
2:15 PM
A Survival Mediation Model with Bayesian Model Averaging
Jie Zhou, Cleveland Clinic Foundation ; Peng Wei, The University of Texas MD Anderson Cancer Center; Brian Hobbs, The University of Texas at Austin
2:35 PM
Predicting Outcomes of Phase III Oncology Trials with Bayesian Mediation Modeling
Jie Zhou, Cleveland Clinic Foundation; Xun Jiang, Amgen; Amy Xia, Amgen; Peng Wei, The University of Texas MD Anderson Cancer Center; Brian Hobbs, The University of Texas at Austin
2:55 PM
Discussant: Stijn Vansteelandt, Ghent University
3:15 PM
Floor Discussion
190 !
Tue, 8/10/2021,
1:30 PM -
3:20 PM
Virtual
Synergy of Bayesian, Frequentist, and Fiducial Approaches in Addressing Modern Statistical Problems in Data Science — Invited Papers
Section on Bayesian Statistical Science , General Methodology, ENAR
Organizer(s): Radu V Craiu, University of Toronto
Chair(s): Hary Iyer, National Institute of Standards and Technology
1:35 PM
Uncertainty Quantification for Object Boundaries Extracted from Spatial Point Patterns
Thomas C. M. Lee, University of California at Davis
2:00 PM
Robust and individualized conformal predictive inference in survival analysis
Minge Xie, Rutgers University
2:25 PM
Uncertainty in Estimation of ROC Curves with Applications to Forensic Science
Presentation
Jan Hannig, University of North Carolina at Chapel Hill ; Hary Iyer, National Institute of Standards and Technology
2:50 PM
Discussant: Xiao-Li Meng, Harvard University
3:10 PM
Floor Discussion
191 * !
Tue, 8/10/2021,
1:30 PM -
3:20 PM
Virtual
Statistical Research in Rapid Response to COVID-19 Pandemic: Forecasts, Risk Factors, Therapeutics, and Vaccine Trials — Invited Papers
Health Policy Statistics Section , ENAR, Biometrics Section
Organizer(s): Yuanjia Wang, Columbia University
Chair(s): Shanghong Xie , Columbia Unviersity
1:35 PM
COVID-19 Forecasts and Scenarios for the United States
Bobby Reiner, University of Washington
1:55 PM
A Hierarchical Epidemic Model to Estimate the Time-Varying Reproduction Numbers and Prevalence of COVID-19 Infections Accounting for Under-Reporting and Delayed Reporting of Cases
Rounak Dey, Harvard T.H. Chan School of Public Health ; Haoyu Zhang, Harvard T.H. Chan School of Public Health; Corbin Quick, Harvard T.H. Chan School of Public Health; Xihong Lin, Harvard T.H. Chan School of Public Health
2:15 PM
Dynamic Risk Assessment of COVID-19 Hospitalization from Electronic Health Records (EHRs)
Yuanjia Wang, Columbia University
2:35 PM
Statistical Aspects of COVID-19 Vaccine Trials
Dean Follmann, NIH
2:55 PM
Discussant: Donglin Zeng, UNC Chapel Hill
3:15 PM
Floor Discussion
207 * !
Tue, 8/10/2021,
1:30 PM -
3:20 PM
Virtual
Distinctive Statistical Considerations in Nursing Education and Research — Topic-Contributed Panel
ENAR , Section on Teaching of Statistics in the Health Sciences, Biometrics Section
Organizer(s): Matthew J Hayat, Georgia State University
Chair(s): Todd Schwartz, University of North Carolina at Chapel Hill
1:35 PM
Distinctive Statistical Considerations in Nursing Education and Research
Panelists:
Matthew J Hayat, Georgia State University
Melinda Higgins, Emory University
Myoungjin Kim, Illinois State University
Wei Pan, Duke University
Yelena Perkhounkova, The University of Iowa
3:15 PM
Floor Discussion
224 * !
Wed, 8/11/2021,
10:00 AM -
11:50 AM
Virtual
New Insights from Analyzing Functional Data in Biomedical Research — Invited Papers
ENAR , Biometrics Section, International Chinese Statistical Association
Organizer(s): Wei Yang, University of Pennsylvania
Chair(s): Wensheng Guo, University of Pennsylvania
10:05 AM
Spatiotemporal Modeling of Distributional Climate Data Using Semiparametric Quantile Functional Regression
Jeffrey S. Morris, University of Pennsylvania Perelman School of Medicine ; Hojin Yang, Pusan National University; Veerabhadran Baladandayuthapani, University of Michigan; Birgir Hrafnkelsson, University of Iceland
10:30 AM
A Sequential Monte Carlo Gibbs Coupled with Stochastically Approximated Expectation-Maximization Algorithm for Functional Data
Ziyue Liu, Indiana University School of Medicine
10:55 AM
Simultaneous Curve Registration and Clustering of Digital Electrocardiogram
Wei Yang, University of Pennsylvania ; Wensheng Guo, University of Pennsylvania
11:20 AM
A Latent Class Functional Mixed Effects Model for Flexible Longitudinal Data Clustering
Tianhao Wang, Rush University Medical Center
11:45 AM
Floor Discussion
233 * !
Wed, 8/11/2021,
10:00 AM -
11:50 AM
Virtual
Evaluating Individualized Predictions of Risk and Benefit for Clinical Use — Topic-Contributed Papers
WNAR , Biometrics Section, ENAR
Organizer(s): Hormuzd Katki, National Cancer Institute
Chair(s): Debamita Kundu, NIH/NCI
10:05 AM
Model-Based ROC (MROC) Curve: Examining the Effect of Case-Mix and Model Calibration on the ROC Plot
Presentation
Mohsen Sadatsafavi, The University of British Columbia ; Paramita Saha-Chaudhuri, University of Vermont; John Petkau, The University of British Columbia
10:25 AM
Moving from Individualized Risk-Based Prevention to Benefit-Based Prevention: Estimating Individualized Life-Years Gained from Prevention Services
Li C Cheung, US National Cancer Institute ; Anil Chaturvedi, National Cancer Institute; Hormuzd Katki, National Cancer Institute
10:45 AM
Using Stochastic Orders to Evaluate Performance of Predictive Models: Intransitivity, Area Under the ROC, and Strength of Stochastic Order Relationships
Olga Demler, Harvard University
10:55 AM
Discussant: Gene Pennello, FDA
11:25 AM
Floor Discussion
273 * !
Wed, 8/11/2021,
1:30 PM -
3:20 PM
Virtual
Statistical Methods for Causal Inference and Personalized Medicine Based on Observational Data — Topic-Contributed Papers
ENAR , International Chinese Statistical Association, International Indian Statistical Association
Organizer(s): Maiying Kong, University of Louisville
Chair(s): Mark Meyer, Georgetown University
1:35 PM
Estimation of Average Treatment Effects Among Multiple Treatment Groups by Using an Ensemble Approach
Maiying Kong, University of Louisville
1:55 PM
A Multiple Robust Propensity Score Method for Longitudinal Analysis with Intermittent Missing Data
Ming Wang, Penn State Milton S Hershey Medical Center ; Chixiang Chen, University of Pennsylvania; Biyi Shen, Penn State Milton S Hershey Medical Center; Rongling Wu, Penn State Milton S Hershey Medical Center; Aiyi Liu, National Institute of Child Health and Human Development
2:15 PM
Personalized Treatment Selection Using Observational Data
Presentation
Sudaraka Tholkage, University of Louisville ; KB Kulasekara, University of Louisville; Maiying Kong, University of Louisville
2:35 PM
Weighted ?^2 Test and F Test for Multiple Group Comparisons in Observational Studies
Xiaofang Yan, Medpace, Inc. ; Qi Zheng, University of Louisville; Maiying Kong, University of Louisville
2:55 PM
Optimal Personalized Treatment Selection with Multiple Outcomes
Susmita Datta, University of Florida
3:15 PM
Floor Discussion
278 * !
Wed, 8/11/2021,
1:30 PM -
3:20 PM
Virtual
Innovative Methods for Predicting Public Health Outcomes and Informing Policy — Topic-Contributed Papers
Section on Statistics in Epidemiology , ENAR, Health Policy Statistics Section
Organizer(s): Ashley Buchanan, College of Pharmacy, University of Rhode Island
Chair(s): Anarina Murillo, Brown University
1:35 PM
Spillover Effects of Pre-Exposure Prophylaxis Delivery for HIV Prevention: Evaluating the Importance of Effect Modification using an Agent-Based Model
Ashley Buchanan, College of Pharmacy, University of Rhode Island ; Carolyn Park, Brown School of Public Health; Sam Bessey, Brown School of Public Health; William Goedel, Brown School of Public Health; Eleanor Murray, Boston University; Samuel Friedman, Department of Population Health, NYU Grossman School of Medicine; M. Elizabeth Halloran, Public Health Sciences Division, Fred Hutch; Natallia Katenka, Department of Computer Science and Statistics, University of Rhode Island; Brandon DL Marshall, Brown School of Public Health
1:55 PM
Multilevel Network Models for Evaluation of Network-Informed HIV Prevention Interventions
Nicole Bohme Carnegie, Montana State University
2:15 PM
Novel Application of a Multistate Model to Investigate the Opioid Use Disorder Care Cascade in Rhode Island
Hilary Aroke, University of Rhode Island ; Ashley Buchanan, College of Pharmacy, University of Rhode Island; Anarina Murillo, Brown University; Tianyu Sun, University of Rhode Island; Jeffrey Bratberg, University of Rhode Island; Stephen Kogut, University of Rhode Island; Brandon DL Marshall, Brown School of Public Health; Joseph Hogan, Brown University
2:35 PM
Cardiovascular Health Inequities: Innovative Methods Coupled with Diverse Observational Cohorts Equals a Recipe for Evidence-Based Policies
Loni Tabb, Drexel Univerisity
2:55 PM
Discussant: Joseph Hogan, Brown University
3:15 PM
Floor Discussion
297
Wed, 8/11/2021,
3:30 PM -
5:20 PM
Virtual
Recent Statistical Advances for Mobile Health — Invited Papers
Biometrics Section , ENAR, WNAR
Organizer(s): Walter Dempsey, University of Michigan
Chair(s): Zhenke Wu, University of Michigan, Ann Arbor
3:35 PM
Recurrent Event Analysis in the Presence of Real-Time High-Frequency Data via Random Subsampling
Walter Dempsey, University of Michigan
3:50 PM
Regularized Greedy Gradient Q-Learning with Mobile Health Applications
Min Qian, Columbia University
4:05 PM
Physical Activity Is the Strongest Modifiable Risk Factor for Mortality: A Short Story Based on NHANES and UK Biobank Data
Ciprian Crainiceanu, Johns Hopkins University
4:20 PM
Safe learning methods for mHealth
Eric Laber, Duke University
4:35 PM
Causal Inference Under Unmeasured Confounding With Negative Controls: A Minimax Learning Approach
Nathan Kallus, Cornell University
4:50 PM
Scalar on time-by-distribution regression and its application to modelling cognitive function in Alzheimer's Disease
Vadim Zipunnikov, Johns Hopkins Bloomberg School of Public Health
5:05 PM
Floor Discussion
300 !
Wed, 8/11/2021,
3:30 PM -
5:20 PM
Virtual
Addressing Statistical Challenges of the COVID-19 Crisis — Invited Papers
ENAR , International Chinese Statistical Association, Biometrics Section
Organizer(s): Jing Huang, University of Pennsylvania Perelman School of Medicine
Chair(s): Jiasheng Shi, University of Pennsylvania Perelman School of Medicine
3:35 PM
Transmission Dynamic Modeling for COVID-19 Data in US and the World
Haoyu Zhang, Harvard T.H. Chan School of Public Health ; Chaolong Wang, Huazhong University of Science and Technology; Xihong Lin, Harvard T.H. Chan School of Public Health
4:00 PM
Curating a COVID-19 Data Repository and Forecasting County-Level Death Counts in the United States
Presentation
Nick Altieri, University of California, Berkeley; Rebecca L Barter, University of California, Berkeley; James Duncan, University of California, Berkeley; Raaz Dwivedi, University of California, Berkeley; Karl Kumbier, University of California, San Francisco; Xiao Li, University of California, Berkeley; Robert Netzorg, University of California, Berkeley; Briton Park, University of California, Berkeley; Chandan Singh, University of California, Berkeley; Yan Shuo Tan, University of California, Berkeley; Tiffany Tang, University of California, Berkeley ; Yu Wang, University of California, Berkeley; Chao Zhang, University of California, Santa Barbara; Bin Yu, University of California, Berkeley
4:25 PM
A Semiparametric Regression Model with Online Estimation Algorithm for Dynamics of Disease Transmission
Jing Huang, University of Pennsylvania Perelman School of Medicine ; Jiasheng Shi, University of Pennsylvania Perelman School of Medicine ; David Rubin, Children's Hospital of Philadelphia; Jeffrey S. Morris, University of Pennsylvania Perelman School of Medicine
4:50 PM
Genetic Variants Are Identified to Increase Risk of COVID-19-Related Mortality from UK Biobank Data
Cai Li, Yale University ; Jianchang Hu, Yale University; Shiying Wang, Yale University; Ting Li, Yale University; Heping Zhang, Yale University
5:15 PM
Floor Discussion
334 * !
Thu, 8/12/2021,
10:00 AM -
11:50 AM
Virtual
Functional and Geometric Approaches for Imaging Data — Invited Papers
Section on Statistics in Imaging , ENAR, Biometrics Section
Organizer(s): Shariq Mohammed, University of Michigan
Chair(s): Veerabhadran Baladandayuthapani, University of Michigan
10:05 AM
Machine Learning Frameworks for Association Mapping with 3D Shapes and High-Resolution Imaging
Lorin Crawford, Microsoft Research
10:30 AM
Tumor Radiogenomics with Bayesian Layered Variable Selection
Shariq Mohammed, University of Michigan ; Sebastian Kurtek, The Ohio State University; Karthik Bharath, University of Nottingham; Arvind Rao, University of Michigan; Veerabhadran Baladandayuthapani, University of Michigan
10:55 AM
Simultaneous Registration and Estimation of Fractional Anisotropy Profiles from Fragmented and Noisy Observations
Sebastian Kurtek, The Ohio State University ; James Matuk, Department of Statistics, The Ohio State University; Oksana Chkrebtii, The Ohio State University; Karthik Bharath, University of Nottingham
11:20 AM
Learning Temporal Evolution of Spatial Dependence with Non-separable, Non-stationary Gaussian Process Models
Shiwei Lan, Arizona State University
11:45 AM
Floor Discussion
338 * !
Thu, 8/12/2021,
10:00 AM -
11:50 AM
Virtual
Advice for Junior Researchers on How to Become a Better Mentor and Lead a Research Group — Invited Panel
ENAR , Biometrics Section, Committee on Career Development
Organizer(s): Joseph Antonelli, University of Florida
Chair(s): Naomi Brownstein, Moffitt Cancer Center
10:05 AM
Advice for Junior Researchers on How to Become a Better Mentor and Lead a Research Group
Panelists:
Brian Caffo, Johns Hopkins University
Susan Paddock, NORC at the University of Chicago
Paul S. Albert, National Cancer Institute
Brisa Sanchez, Drexel University
11:40 AM
Floor Discussion
342 * !
Thu, 8/12/2021,
10:00 AM -
11:50 AM
Virtual
Measurement Challenges and Innovations in Cognitive Aging and Dementia Research: Progress from the MEthods for LOngitudinal Studies of DEMentia (MELODEM) Initiative — Topic-Contributed Papers
Section on Statistics in Epidemiology , WNAR, ENAR
Organizer(s): Crystal Shaw, UCLA Fielding School of Public Health
Chair(s): Shubhabrata Mukherjee, University of Washington
10:05 AM
Co-Calibrating Cognitive Scores Across Multiple Studies of Dementia
Laura Gibbons, University of Washington ; Paul K Crane, University of Washington; Shubhabrata Mukherjee, University of Washington
10:25 AM
Co-Calibration of Cognitive Functioning Domains Across Different Countries When There Are No Common Linking Items
Alden Gross, Johns Hopkins Bloomberg School of Public Health ; Emma L Nichols, Johns Hopkins Bloomberg School of Public Health
10:45 AM
A Bayesian latent class mixture modeling framework for algorithmic dementia classification in population-representative studies
Crystal Shaw, UCLA Fielding School of Public Health ; donatello telesca, UCLA; Elizabeth Rose Mayeda, UCLA FSPH; Thomas R. Belin, UCLA FSPH
11:05 AM
Sensitivity Analysis for Nonignorable Missingness and Outcome Misclassification from Proxy Reports
Michelle Shardell, University of Maryland School of Medicine
11:25 AM
Integrating Latent Variable Modeling, Statistical Learning, and Inverse Propensity Score Weighting to Identify Longitudinal Trajectory Phenotypes and the Underlying Disparity
Presentation
Chen-Pin Wang, University of Texas Health Science Center San Antonio ; Mitzi M Gonzales, University of Texas Health Science Center San Antonio; Helen Hazuda, University of Texas Health Science Center San Antonio; Sudha Seshadri, University of Texas Health Science Center San Antonio
11:45 AM
Floor Discussion
366 *
Thu, 8/12/2021,
12:00 PM -
1:50 PM
Virtual
Trial Design and Analysis Methods for COVID-19 Treatment/Prevention — Invited Papers
ENAR , Biopharmaceutical Section, Biometrics Section, Caucus for Women in Statistics
Organizer(s): Michael Rosenblum, Johns Hopkins University
Chair(s): Bingkai Wang, Johns Hopkins Bloomberg School of Public Health
12:05 PM
Improving Precision and Power in Randomized Trials for COVID-19 Treatments Using Covariate Adjustment for Binary, Ordinal, or Time-to-Event Outcomes
David Benkeser, Emory University ; Ivan Diaz, Weill Cornell Medical College; Alex Luedtke, University of Washington; Daniel Scharfstein, University of Utah; Jodi Seagal, Johns Hopkins University; Michael Rosenblum, Johns Hopkins University
12:30 PM
Clinical Trials Impacted by the COVID-19 Pandemic: Adaptive Designs to the Rescue?
Cornelia Kunz, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany ; Silke Jörgens, Janssen-Cilag GmbH, Neuss, Germany ; Frank Bretz, Novartis AG; Nigel Stallard, The University of Warwick, Coventry, UK; Kelly Van Lancker, Ghent University, Belgium ; Dong Xi, Novartis Pharmaceuticals, East Hanover, New Jersey, USA ; Sarah Zohar, Sorbonne Université, Paris, France; Christoph Gerlinger, Statistics and Data Insights, Bayer AG, Berlin, Germany ; Tim Friede, University Medical Center Göttingen, Göttingen, Germany
12:55 PM
Challenges in clinical trial design during a pandemic: Experiences from the UK and beyond
Thomas Jaki, University of Cambridge
1:20 PM
Discussant: Laura Lee Johnson, Center for Drug Evaluation and Research, U.S. FDA
1:40 PM
Floor Discussion
397 * !
Thu, 8/12/2021,
2:00 PM -
3:50 PM
Virtual
Personalized Medicine with Large-Scale Data: Beyond Machine Learning — Invited Papers
ENAR , Lifetime Data Science Section, International Chinese Statistical Association
Organizer(s): Yichuan Zhao, Georgia State University
Chair(s): Yichuan Zhao, Georgia State University
2:05 PM
Inference for High-Dimensional Censored Quantile Regression
Yi Li, University of Michigan
2:30 PM
Testing a High-Dimensional Parameter in the Presence of High-Dimensional Nuisance Parameters
Wei Pan, University of Minnesota
2:55 PM
Personalized Medicine with Large-Scale Data: Beyond Machine Learning
Ross Laverne Prentice, Fred Hutchinson Cancer Research Center
3:20 PM
Discussant: Ian McKeague, Columbia University
3:45 PM
Floor Discussion
402 !
Thu, 8/12/2021,
2:00 PM -
3:50 PM
Virtual
Integrative Inference with Data from Multiple Sources: Challenges and New Developments — Topic-Contributed Papers
ENAR , IMS, Section on Statistical Computing
Organizer(s): Emily C Hector, North Carolina State University
Chair(s): Emily C Hector, North Carolina State University
2:05 PM
Integrating Multisource Block-Wise Missing Data in Model Selection
Fei Xue, University of Pennsylvania ; Annie Qu, Unviersity of California Irvine
2:25 PM
Integrative Factor Regression and Its Inference for Multimodal Data Analysis
Quefeng Li, University of North Carolina at Chapel Hill ; Lexin Li, University of California, Berkeley
2:45 PM
Federated Learning Approaches for Integrative Analysis of Heterogeneous Data Sources
Lu Tang, University of Pittsburgh
3:05 PM
Data Integration with Oracle Use of External Information from Heterogeneous Populations
Peisong Han, University of Michigan
3:25 PM
Causal Inference for Combining RCTs and Observational Studies: Methods Comparison and Medical Application
Presentation
Bénédicte Colnet, INRIA Saclay ; Imke Mayer, Centre d'Analyse et de Mathématiques Sociales, EHESS; Guanhua Chen, Department of Biostatistics and Medical Informatics, University of Winsconsin-Madison; Awa Dieng, Google Research; Ruohong Li, Indiana University School of Medicine; Gaël Varoquaux, INRIA Saclay; Jean-Philippe Vert, Google Research; Julie Josse, INRIA Sophia-Antipolis; Shu Yang, North Carolina State University
3:45 PM
Floor Discussion
418 *
Thu, 8/12/2021,
4:00 PM -
5:50 PM
Virtual
Recent Developments in Network Meta-Analysis — Invited Papers
ENAR , International Chinese Statistical Association, Section on Statistics in Epidemiology
Organizer(s): Haitao Chu, University of Minnesota Twin Cities
Chair(s): Rui Duan, Harvard University
4:05 PM
The Impact of Covariance Priors on Arm-Based Bayesian Network Meta-Analyses with Binary Outcomes
Zhenxun Wang, University of Minnesota Twin Cities; Lifeng Lin, Florida State University; James Hodges, University of Minnesota Twin Cities; Haitao Chu, University of Minnesota Twin Cities
4:30 PM
Assessment of Homogeneity and Consistency for Network Meta-Analysis
Joseph G Ibrahim, UNC ; Cheng Zhang, UCONN; Hao Li, Boeringer-Ingelheim; Ming-Hui Chen, UCONN; Arvind Shah, Merck, Inc.; Jianxin Lin, Merck, Inc.
4:55 PM
Predictive Treatment Ranking in Bayesian Network Meta-Analysis
Lifeng Lin, Florida State University
5:20 PM
Bayesian Network Meta-Regression Hierarchical Models Using Heavy-Tailed Multivariate Random Effects with Covariate-Dependent Variances
Hao Li, University of Connecticut; Daeyoung Lim, University of Connecticut; Ming-Hui Chen, UCONN ; Joseph G Ibrahim, UNC; Sungduk Kim, National Cancer Institute; Arvind Shah, Merck, Inc.; Jianxin Lin, Merck, Inc.
5:45 PM
Floor Discussion
421 * !
Thu, 8/12/2021,
4:00 PM -
5:50 PM
Virtual
Statistical Challenges Linked to Estimands of Interest: Leaving No Stone Unturned — Invited Papers
Biopharmaceutical Section , ENAR, Biometrics Section
Organizer(s): Pilar Lim, Janssen Research & Development, LLC; Elena Polverejan, Janssen Research & Development, LLC
Chair(s): Elena Polverejan, Janssen Research & Development, LLC
4:05 PM
The Only Missing Data Left in Town? Study Withdrawals and the Treatment Policy Approach
Siying Sylvia Li, IQVIA ; Michael O'Kelly, IQVIA
4:30 PM
The Role of Hypothetical Estimand Strategies in Clinical Trials
Frank Bretz, Novartis AG ; Mouna Akacha, Novartis
4:55 PM
Does This Treatment Cause That Outcome?
Stephen J Ruberg, Analytix Thinking, LLC
5:20 PM
Discussant: H. M. James Hung, U.S. Food and Drug Administration (FDA)
5:45 PM
Floor Discussion
422 !
Thu, 8/12/2021,
4:00 PM -
5:50 PM
Virtual
Recent Development of Machine Learning Methods in Causal Inference — Invited Papers
Section on Statistical Learning and Data Science , ENAR, American Association for the Advancement of Science
Organizer(s): Rui Song, North Carolina State University
Chair(s): Hongtu Zhu, University of North Carolina
4:05 PM
Nonparametric Inverse Probability Weighted Estimators Based on the Highly Adaptive Lasso
Ashkan Ertefaie, University of Rochester ; Nima Hejazi, University of California, Berkeley; Mark Van Der Laan, University of California
4:25 PM
Calibrated Optimal Decision-Making with Multiple Data Sources and Limited Outcome
Hengrui Cai, North Carolina State University
4:45 PM
Estimating Heterogeneous Causal Effects of High-Dimensional Treatments: Application to Conjoint Analysis
Max Goplerud, University of Pittsburgh; Kosuke Imai, Harvard University ; Nicole E Pashley, Rutgers University
5:05 PM
Almost Matching Exactly
Cynthia Rudin, Duke University; Alexander Volfovsky, Duke University ; Sudeepa Roy, Duke University
5:25 PM
Discussant: Jelena Bradic, University of California, San Diego
5:45 PM
Floor Discussion
432 * !
Thu, 8/12/2021,
4:00 PM -
5:50 PM
Virtual
Novel Statistical Methods for Microbiome Data Analysis — Topic-Contributed Papers
Section on Statistics in Genomics and Genetics , Biometrics Section, ENAR
Organizer(s): Xiang Zhan , Penn State University
Chair(s): Arun Srinivasan, Penn State University
4:05 PM
Controlled Microbiome Variable Selection Analysis
Xiang Zhan , Penn State University ; Arun Srinivasan, Penn State University; Lingzhou Xue, Penn State University and National Institute of Statistical Sciences
4:25 PM
Corncob: Statistical Modeling of Microbial Abundances and Dysbiosis with Beta-Binomial Regression
Bryan D Martin, University of Washington ; Daniela Witten, University of Washington; Amy D Willis, University of Washington
4:45 PM
Meta-Analysis of Microbiome Studies for Selecting Disease-Associated Microbial Signatures
ZhengZheng Tang, University of Wisconsin-Madison
5:05 PM
Rarefaction-Based Extensions of the LDM and PERMANOVA for Testing Presence-Absence Associations in the Microbiome
Yijuan Hu, Emory University ; Andrea Lane, Emory University; Glen Satten, Emory University
5:25 PM
Dimension Reduction of Longitudinal Microbiome Data via Tensor Functional SVD
Pixu Shi, Duke University ; Rungang Han, University of Wisconsin-Madison; Anru Zhang, Duke University
5:45 PM
Floor Discussion