This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.
Abstract Details
Activity Number:
|
445
|
Type:
|
Invited
|
Date/Time:
|
Wednesday, August 4, 2010 : 8:30 AM to 10:20 AM
|
Sponsor:
|
Section on Statistical Consulting
|
Abstract - #305921 |
Title:
|
Exon-Based Microarrays and Their Applications in Personalized Health Care
|
Author(s):
|
Wei-min Liu*+ and Yu Chuan Tai and Yan Li
|
Companies:
|
Roche Molecular Systems, Inc. and Roche Molecular Systems, Inc. and Roche Molecular Systems, Inc.
|
Address:
|
4300 Hacienda Dr., Pleasanton, CA, 94588,
|
Keywords:
|
diagnostics ;
personalized medicine ;
microarray ;
molecular profiling ;
exon ;
normalization
|
Abstract:
|
We propose to use the new DQN signals for the exon-based microarrays at both the exon level and gene (transcript cluster) level. We also suggest simple quality control measures. One of the benefits of using DQN signals is that the signals for a single microarray are not dependent on other microarrays in a study, therefore, the cross validation or training and testing for classification can be performed in a setting that the normalization of training dataset is completely irrelevant to the testing dataset. We also check the probe sequence contents with the current RefSeq database. We consider the possible applications of our approach to personalized health care through gene expression profiling, alternative splicing and pathway analysis.
|
The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
Back to the full JSM 2010 program
|
2010 JSM Online Program Home
For information, contact jsm@amstat.org or phone (888) 231-3473.
If you have questions about the Continuing Education program, please contact the Education Department.