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Sunday, 08/01/2010
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Follow-Up of Subjects in Event Rates for Periodic Safety Monitoring Reports in Open Enrollment Clinical Trials
Maria Carola Alfaro, Boston Scientific Corporation
4:05 PM
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A Parametric Test for Correlated Time-to-Event Data with a Failure Rate Change
Gang Han, Moffitt Cancer Center & Research Institute; Ji-Hyun Lee, Moffitt Cancer Center & Research Institute
4:05 PM
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On the Clinical Meaningfulness of a Treatment's Effect on a Time-to-Event Variable
Qi Jiang, Amgen Inc.; Steven Snapinn, Amgen Inc.
4:05 PM
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An Application of Semiparametric Bayesian Isotonic Regression to the Study of Radiation Effects in Spaceborne Microelectronics
Marian Farah, University of California, Santa Cruz; Athanasios Kottas, University of California, Santa Cruz; Robin D. Morris, Universities Space Research Association
4:25 PM
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Sequential Analytic Methods for Prospective Drug Safety Surveillance
Lingling Li, Harvard Medical School/Harvard Pilgrim Health Care Institute
4:30 PM
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Using Bayesian Adaptive Designs for FDA Event Safety Studies
Jason Connor, Berry Consultants, LLC; Scott Berry, Berry Consultants, LLC; Donald Arthur Berry, MD Anderson Cancer Center
4:45 PM
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Interval-Censored Time-to-Event Data in Clinical Trials: Analyzing and Designing
Xing Sun, Merck & Co., Inc.; Cong Chen, Merck & Co., Inc.
4:50 PM
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Assessing the Causal Effect of Treatment Dosages in the Presence of Self-Selection
Xin Gao, University of Michigan; Michael R. Elliott, University of Michigan
5:05 PM
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Monday, 08/02/2010
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Health, Disability, and Employment Status Effects of a Diabetes Management Life Coaching and Pharmacist Counseling Intervention
Tammy Tom, The University of Hawaii
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ROC Regression Using Percentile Values for Event Time Outcomes
Yuying Jin, University of Washington; Margaret Sullivan Pepe, Fred Hutchinson Cancer Research Center; Yingye Zheng, Fred Hutchinson Cancer Research Center
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Globalization of Biostatistics: The Development Treatments and Preventative Products for Infectious Diseases
Tammy Massie, FDA/CBER
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Classroom Activities for Investigating the Occurrence of Two Unusual Events
Kate Thomas, California State University, Chico; Neil C. Schwertman, California State University, Chico
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Informative Array Screening
Christopher Steven McMahan, University of South Carolina; Joshua Tebbs, University of South Carolina
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Topics on Analyzing Recurrent Event Data with Sparsely Observed Longitudinal Information
Ye Shen, Yale University; Yongtao Guan, Yale University
8:35 AM
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Optimal Two-Stage Phase II Design Utilizing Partial Information for Long-Term Endpoints
Bo Huang, Pfizer Inc.; Enayet Talukder, Pfizer Inc.; Neal Thomas, Pfizer Inc.
9:35 AM
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Approximating Probabilities of Correlated Events
Qizhai Li, Chinese Academy of Sciences; Gang Zheng, National Institutes of Health; Aiyi Liu, Eunice Kennedy Shriver National Institute of Child Health and Human Development; Zhaohai Li, The George Washington University; Kai Yu, National Cancer Institute
9:35 AM
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Globalization of Biostatistics: The Development Treatments and Preventative Products for Infectious Diseases Including Applications in H1N1, Travelers Diarrhea, and/or Malaria
Tammy Massie, FDA/CBER
9:55 AM
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Semiparametric Regression Inference for Tumor Progression in Cancer Studies
Chen Hu, University of Michigan; Alexander Tsodikov, University of Michigan
11:20 AM
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A Bayesian Shrinkage Model for Incomplete Longitudinal Binary Data with Application to the Breast Cancer Prevention Trial
Chenguang Wang, FDA; Michael J. Daniels, University of Florida; Daniel O. Scharfstein, Johns Hopkins Bloomberg School of Public Health; Stephanie R. Land, University of Pittsburgh
11:35 AM
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Diversity in a Sample and Large Number of Small Probabilities: The Case of Questionnaires
Estate V. Khmaladze, Victoria University of Wellington
2:05 PM
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Bayesian Meta-Analysis of Rare Events Incorporating Historical Controls
Yan Zheng, sanofi-aventis; Xin Zhi, sanofi-aventis
2:05 PM
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A Joint Model of Longitudinal Data and Time-to-Event Data with Cure Fraction
Ashok Panneerselvam, Case Western Reserve University; Mark Schluchter, Case Western Reserve University
2:05 PM
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Analysis of Recurrent Event Data in the Presence of Terminal Events and Missing Covariates
Shankar Viswanathan, The University of North Carolina at Chapel Hill; Jianwen Cai, The University of North Carolina at Chapel Hill
2:20 PM
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An Individual-Patient Meta-Analytic Mixed Model with Repeated Measures and Time-Dependent Covariates: An Application to Adverse Event Data
Sofia Paul, Novartis Pharmaceuticals Corporation; Stephanie Ann Kovalchik, University of California, Los Angeles; Jing Hu, Novartis Pharmaceuticals Corporation; Glen Laird, Novartis Pharmaceuticals Corporation
2:20 PM
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Fitting High-Dimensional Joint Models for Longitudinal and Time-to-Event Data Using Laplace Approximations
Dimitris Rizopoulos, Erasmus University Medical Center
2:45 PM
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A Joint Model for the Analysis of Multiscale Time to Events and Longitudinal Binary Data
Rajeshwari Sundaram, Eunice Kennedy Shriver National Institute of Child Health and Human Development; Alexander Mclain, Eunice Kennedy Shriver National Institute of Child Health and Human Development; Paul S. Albert, Eunice Kennedy Shriver National Institute of Child Health and Human Development; Germaine M. Buck Louis, Eunice Kennedy Shriver National Institute of Child Health and Human Development; Kirsten J. Lum, The Johns Hopkins University
3:05 PM
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Tuesday, 08/03/2010
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On the Repeated Estimation of Survival Time Quantiles for a Time-to-Event Study in Follow-Up Stage
Sunhee Kwon Ro, Onyx Pharmaceuticals; Yu-Lin Chang, Onyx Pharmaceuticals
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Statistical Models for Adenoma Data from Colorectal Polyp Prevention Trials
Chiu-Hsieh Hsu, The University of Arizona; Sadhvi Khanna, The University of Arizona
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Cox Regression Model with Time-Dependant Covariates to Investigate the Impacts of Nonfatal Events on Subsequent Mortality
Huyuan Yang, Boston Scientific Corporation; Hong Wang, Boston Scientific Corporation; Heather Bai, Boston Scientific Corporation
8:35 AM
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Application of Bayesian Joint Modeling of Time-to-Event and Patient-Reported Outcomes in an Oncology Clinical Trial
Luping Zhao, Eli Lilly and Company; Wei Shen, Eli Lilly and Company; Haoda Fu, Eli Lilly and Company ; Michelle Denise Hackshaw, Eli Lilly and Company; Mark E. Boye, Eli Lilly and Company
9:15 AM
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A Frailty-Model-Based Approach to Estimating the Age-Dependent Penetrance Function of a Gene Mutation Using Family-Based Study Designs
Yun-Hee Choi, The University of Western Ontario; Laurent Briollais, Samuel Lunenfeld Research Institute
9:35 AM
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Identifying Temporal Pattern of Adverse Events in Drug-Eluting Stents Studies
Aijun Song, Boston Scientific Corporation; Huyuan Yang, Boston Scientific Corporation; Hsini Terry Liao, Boston Scientific Corporation; Jeff Hersh, Boston Scientific Corporation
9:55 AM
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Meta-Analysis for Rare Adverse Event Data from Clinical Trials
Brenda Crowe, Eli Lilly and Company
10:35 AM
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Asymptotic Properties of Logrank and Stratified Logrank Tests on Highly Stratified Time-to-Event Data
Yabing Mai, Merck Research Laboratories; Sherry Liu, Merck Research Laboratories; Tinghui Yu, Binghamton University
10:50 AM
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Spatial Time-to-Event Analysis of Air Pollution and Preterm Birth
Howard Chang, Statistical and Applied Mathematical Sciences Institute; Brian Reich, North Carolina State University; Marie Lynn Miranda, Duke University
11:15 AM
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Sample-Size Calculation for Time-to-Event Outcome with Treatment Lag Effect
Yulei Zhang, Columbia University; Tai-Tsang Chen, Bristol-Myers Squibb/Columbia University
11:20 AM
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A Bivariate Mover-Stayer Model for Interval-Censored Recurrent Event Data: Application to Joint Damage in Rheumatology
Rinku Sutradhar, Institute for Clinical Evaluative Sciences
11:50 AM
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A Novel Rank Rest for a Time-to-Event Outcome That Incorporates Information on a Surrogate Event
Pamela A. Shaw, National Institute of Allergy and Infectious Diseases; Michael P. Fay, National Institute of Allergy and Infectious Diseases
2:05 PM
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Sample-Size Calculation for the Andersen-Gill Model in the Presence of Subject Heterogeneity in the Baseline Risk
Antje Jahn-Eimermacher, University of Mainz; Katharina Ingel, University of Mainz
2:20 PM
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A Case Study of the Relative Differences in the Recording of Ethnicity in Birth Records and in the Census: The Hispanic Population of Los Angeles County, California
David A. Swanson, University of California, Riverside; Matt Kaneshiro, University of California, Riverside; Amanda Martinez, University of California, Riverside
2:50 PM
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Approximate Confidence Limits for a Proportion of the Hypergeometric Probability Distribution: Applications in Audits, Acceptance Sampling and Medical Investigations
Yevgeniy Voinov, KIMEP
2:50 PM
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Wednesday, 08/04/2010
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Bias Correction for Rare Events in Self-Controlled Case Series Design of Vaccine Safety
Chan Zeng, Kaiser Permanente Colorado; Jason M. Glanz, Kaiser Permanente Colorado; Sophia R. Newcomer, Kaiser Permanente Colorado; Stanley Xu, Kaiser Permanente Colorado
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Nonparametric Estimation of Time Trend for Recurrent Events Data
Bo Henry Lindqvist, Norwegian University of Science and Technology
8:35 AM
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Evaluation of the Marital Events Items on the ACS
Diana B. Elliott, U.S. Census Bureau; Tavia Simmons, U.S. Census Bureau; Jamie M. Lewis, The University of North Carolina at Chapel Hill
8:55 AM
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Computationally Efficient Marginal Models for Recurrent Event Data
Dandan Liu, University of Michigan; Douglas E. Schaubel, University of Michigan; John David Kalbfleisch, University of Michigan
9:05 AM
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Testing Small Center Events in Multicenter Trials Using Survival Modeling
Usha Sita Govindarajulu, Brigham and Women's Hospital, Harvard Medical School; Elizabeth J. Malloy, American University; James Dziura, Yale University
9:05 AM
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Longitudinal Data Analysis with Event Time as a Covariate
Xuewen Lu, University of Calgary; Bin Nan, University of Michigan; Peter Song, University of Michigan; MaryFran Sowers, University of Michigan
9:15 AM
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Studying Simulated Mass Layoff Events and Employment/Unemployment Data with Factor Analysis, Multiple Regression, and Bayesian Methods
Zhe (Jason) Liu, Iowa State University; Mack Shelley, Iowa State University
9:20 AM
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The Reliability of Signal Analysis in the Adverse Events Setting of Priorities
Qian Graves, FDA/CFSAN; Peng T. Liu, FDA; Stuart Chirtel, FDA/CFSAN; Curtis Barton, FDA/CFSAN; Debra Street, FDA/CFSAN
9:20 AM
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A Joint Model of Recurrent Events and a Terminal Event with a Nonparametric Covariate Function
Zhangsheng Yu, Indiana University School of Medicine; Lei Liu, University of Virginia
9:35 AM
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Analyses of Recurrent Events with Informative Censoring
Joan Hu, Simon Fraser University
9:35 AM
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The Value of Personalized, Predictive Risk-Assessment Tools for the Prevention of Chronic Diseases
Edward J. Moler, Tethys Bioscience, Inc.; Louis P. Garrison, University of Washington; Janice Kolberg, Tethys Bioscience, Inc.; Harald Rinde, BioBridge Strategies Switzerland; Sean D. Sullivan, University of Washington
9:35 AM
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Intensity-Based Estimation of Extreme Loss Event Probability and Value-at-Risk
Kam Hamidieh, Rice University; Stilian Stoev, University of Michigan; George Michailidis, University of Michigan
10:35 AM
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A Comparison of the Results of Intent-to-Treat, per-Protocol, and g-Estimation in the Presence of Nonrandom Treatment Changes in a Time-to-Event Noninferiority Trial
Yutaka Matsuyama, The University of Tokyo
10:55 AM
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Cancer Risk in the Environment: Public Policy Issues in Screening
Karen Kafadar, Indiana University; Philip Prorok, National Cancer Institute
11:05 AM
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Sensitivity Analyses Adjusting for Early Discontinuation of Study Medication in the RE-LY Trial: An Open-Label, Randomized, Active-Controlled, Time-to-Event Noninferiority Trial
Xiuyu Cong, Boehringer Ingelheim Pharmaceuticals, Inc.; Qiqi Deng, Boehringer Ingelheim Pharmaceuticals, Inc.; Susan Q. Wang, Boehringer Ingelheim Pharmaceuticals, Inc.
11:15 AM
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Sparse Data in Meta-Analysis: Parametric and Semiparametric Models and Parameterization Issues
Arpita Chatterjee, Northern Illinois University; Sanjib Basu, Northern Illinois University
11:15 AM
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A Bayesian Design with the Time-to-Event Endpoint
Qiong Wang, GlaxoSmithKline
11:35 AM
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Comparing Proportions of Extremely Rare Events of Uncertain Status with Applications to Vaccine Safety Studies
Hongyuan Cao, The University of North Carolina at Chapel Hill; Lisa M. LaVange, The University of North Carolina at Chapel Hill; Joseph Heyse, Merck Research Laboratories; Michael Kosorok, The University of North Carolina at Chapel Hill
11:35 AM
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Performance Measures for Survival Prediction Models: An Overview
Linda M. Peelen, Julius Center for Health Sciences and Primary Care UMC Utrecht; Nina P. Paynter, Brigham and Women's Hospital; Karel G.M. Moons, Julius Center for Health Sciences and Primary Care UMC Utrecht; Nancy Cook, Brigham and Women's Hospital
2:05 PM
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Bias in Oncology Time-to-Event Data Analysis
Din Chen, Georgia Southern University; Yuhlong Lio, The University of South Dakota; Yibin Wang, Novartis
2:05 PM
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Multivariate Modeling of Longitudinal Health Care Costs and Time-to-Event Data in Matched Pairs
An Creemers, Universiteit Hasselt; Marc Aerts, Hasselt University; Niel Hens, Hasselt University; Ziv Shkedy, Universiteit Hasselt; Frank De Smet, National Alliance of Christian Mutualities; Philippe Beutels, Universiteit Antwerpen
2:20 PM
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Performance of Prediction Measures in a Survival Setting
Nina P. Paynter, Brigham and Women's Hospital; Linda M. Peelen, Julius Center for Health Sciences and Primary Care UMC Utrecht; Nancy Cook, Brigham and Women's Hospital
2:25 PM
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Correlated Component Regression: A Prediction/Classification Methodology for Possibly Many Features
Jay Magidson, Statistical Innovations Inc.
2:50 PM
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Bayesian Applications in Drug Safety Evaluation
Amy Xia, Amgen Inc.
2:55 PM
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Bayesian Nonparametric Estimation of Regression Models in Event History Analysis
Pierpaolo De Blasi, University of Turin/Collegio Carlo Alberto
3:05 PM
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Modeling Nested Multivariate Longitudinal Count Data with Application to HIV Behavioral Intervention
Yuda Zhu, University of California, Los Angeles; Robert E. Weiss, University of California, Los Angeles School of Public Health
3:05 PM
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Bayesian Dynamic Models for Improved Efficacy in Avoidance of Preventable Hospital Deaths
David Draper, University of California, Santa Cruz
3:20 PM
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Estimation of Odds Ratio with Rare Event Case: A Simulation Study Based on Hospitalized Flu Vaccine Study
Qingxia Chen, Vanderbilt University; Yuwei Zhu, Vanderbilt University; Helen K.B. Talbot, Vanderbilt University; Marie R. Griffin, Vanderbilt University; Kathryn M. Edwards, Vanderbilt University
3:20 PM
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Treatment Strategies: An Evaluation of the Impact of Potential Preventative and Therapeutic Interventions on Costs of Alzheimer's Disease
Elizabeth Colantuoni, The Johns Hopkins University; Ron Brookmeyer, University of California, Los Angeles
3:35 PM
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Thursday, 08/05/2010
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Risk Models for Deciding Whether to Take Tamoxifen to Prevent Breast Cancer and for Allocating Public Health Resources
Mitchell H. Gail, National Cancer Institute
8:35 AM
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Sample Size Re-estimation for a Time-to-event Endpoint Based on Stratified Analysis
Liang Chen, Pfizer Inc.
8:50 AM
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Hypoglycemia Data Analyses in Diabetes Studies
Yu Chen, Merck & Co., Inc.; Yue Shentu, Merck & Co., Inc.; Bret Musser, Merck Research Laboratories
9:35 AM
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Analysis of Correlated Data and Time-to-Event Using the Markov Chain Imbedding Approach
Wendy Lou, University of Toronto
9:55 AM
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Incidence, Prevalence, and Duration in Alternating Events Models
Mei-Cheng Wang, The Johns Hopkins University; Russell T. Shinohara, Johns Hopkins Bloomberg School of Public Health
10:35 AM
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Considerations for Design and Data Analysis of Adaptive Superiority/Noninferiority Cardiovascular Trials
Hui Quan, sanofi-aventis; Mingyu Li, Celgene Corporation; Peng-Liang Zhao, sanofi-aventis; Meehyung Cho, sanofi-aventis; Ji Zhang, Sanofi-Aventis; Yujun Wu, Sanofi-Aventis
10:35 AM
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Bayesian Hierarchical Models for Detecting Safety Signals in Clinical Trials
Haijun Ma, Amgen Inc.; Amy Xia, Amgen Inc.; Bradley P. Carlin, University of Minnesota
10:35 AM
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Using Integrated Difference Between Two Kaplan-Meier Curves for Quantifying Treatment Contrast in Comparative Clinical Trials with Event Time Observations
Lihui Zhao, Harvard School of Public Health
10:35 AM
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Analysis of Number of Recurrent Events with Early Withdrawals
Kim Hung Lo, Johnson & Johnson; Bin Zou, Johnson & Johnson; Jiandong Lu, Johnson & Johnson
11:20 AM
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A Rare Event Model for Growth Dynamics
Dodi Devianto, Andalas University
11:20 AM
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