Online Program

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Thursday, October 3
Thu, Oct 3, 5:00 PM - 7:00 PM
Evergreen Ballroom Prefunction
Opening Mixer and Speed Poster 1

Using Meta-Analysis on Clinical Data to Refute a Common Misconception About Toothpaste (306680)

Aaron Biesbrock, Procter & Gamble 
Joe DiGennaro, Procter & Gamble 
Tao He, Procter & Gamble 
Dave Ramsey, Procter & Gamble 
*Yuanshu Zou, Procter & Gamble 

Keywords: Stannous fluoride, Meta-analysis

“All fluoride toothpastes are the same” is a common misconception in oral health. Seventy-one randomized clinical studies with seven thousand subjects across eight countries worldwide were included in this research. Meta-analyses using inverse variance method with both fixed and random-effects models were done to evaluate bioavailable stannous fluoride toothpastes across various benefit areas: gingivitis, plaque, sensitivity and erosion. The results demonstrate the superiority of bioavailable stannous fluoride toothpastes over toothpastes containing other fluorides and/or active ingredients.