CS025 Lightning Session 5, Part 1 -- SDSS 2026

Change-point modeling of the effect of biologics on survival among metastatic colorectal cancer patients

1:15 PM - 2:45 PM

Co-authors: Abdissa Negassa (Albert Einstein College of Medicine), Abdissa Negassa (Albert Einstein College of Medicine), Sanjay Goel (Rutgers Cancer Institute)

Biochemotherapy Change-point Cox proportional hazards

Clustering-Based Spatial Representation for Molecular Alteration Prediction from Histopathological Images in Prostate Cancer

1:15 PM - 2:45 PM

Co-authors: Lucas Liu (Fred Hutchinson Cancer Center), Mekias Kebede (University of Washington), Mekias Kebede (University of Washington), Ruth Etzioni (Fred Hutchinson Cancer Research Center)

Machine Learning Spatial Representation Histopathology Image Genetic Alterations Prostate Cancer

Win Time in Favor of Treatment: A Statistical Method for Longitudinal Hierarchal Endpoints

1:15 PM - 2:45 PM

Co-authors: Sahil Patel, Sahil Patel, Huiman Barnhart (Duke University), Lu Mao (University of Wisconsin-Madison), Roland Matsouaka, Yuliya Lokhnygina

Hierarchical endpoints Longitudinal clinical data Nonparametric inference U-statistics Composite outcomes Trajectory-based analysis

Developing an OMOP-Standardized Prostate Cancer Database from Electronic Health Records: Data Quality Assessment and Improvement

1:15 PM - 2:45 PM

Co-authors: Jiefei Wang (University of Texas Medical Branch), Jiefei Wang (University of Texas Medical Branch), Anette Garza (University of Texas Medical Branch), Jamaal C. Jackson (University of Texas Medical Branch), Yong-Fang Kuo (University of Texas, Medical Branch)

Prostate Cancer Electronic Health Records OMOP Common Data Model Cancer registry data Natural language processing Clinical data standardization

Enhancing TV Out of Home Measurement: A Total Error Framework

1:15 PM - 2:45 PM

Co-authors: Kyle Poppie (Nielsen), Kyle Poppie (Nielsen)

bias, variance, sampling variability, total survey error nielsen, television, market research, audience measurement applied statistics

Environmental Protection: Development of a Real-Time Multi-Stream Water Quality Monitoring System

1:15 PM - 2:45 PM

Co-authors: Faruk Muritala (Kennesaw State University), Faruk Muritala (Kennesaw State University), Austin Brown, Sherry Ni (Kennesaw State University)

CSB-EWMA control chart

Evaluating Missing Data Assumptions in Longitudinal Trials: A Simulation Study

1:15 PM - 2:45 PM

Co-authors: Kapil Rathi (Corcept Therapeutics), Iulia Cristina Tudor (Corcept Therapeutics Inc), Kapil Rathi (Corcept Therapeutics)

Missing Data Longitudinal Clinical Trails Missing data mechanisms (MAR, MNAR)Sensitivity analyses Simulation study

From Two-Stage Binary Design to Landmark Survival Monitoring

1:15 PM - 2:45 PM

Co-authors: Yuchen Jin (Medical College of Wisconsin), Aniko Szabo (Medical College of Wisconsin), Yuchen Jin (Medical College of Wisconsin)

two-stage phase II design landmark time-to-event outcome Kaplan–Meier estimator clinical trial

Group Sequential Design for Covariate-adjusted Restricted Mean Survival Time Comparisons

1:15 PM - 2:45 PM

Co-authors: Michael Martens (Medical College of Wisconsin), Yikun Shi, Yikun Shi

Restricted mean survival time (RMST)Group sequential design Covariate adjustment Interim analysis Nonproportional hazards Blood and marrow transplantation

Instrumental Variable Estimation of Labor Supply Elasticities in a Function-on-Function Framework

1:15 PM - 2:45 PM

Co-authors: Bahaeddine Taoufik (Saint Joseph's University), Bahaeddine Taoufik (Saint Joseph's University), Justin Petrovich (Saint Vincent College)

Functional Data Instrumental Variables Labor Elasticity two-stage least squares Function-on-Function Regression

Metabolic Pathway Analysis to Uncover Hidden Immune-Metabolic Axes in Clear Cell Renal Cell Carcinoma (ccRCC)

1:15 PM - 2:45 PM

Co-authors: Shivam Chawla, Soyoung Jeon (New Mexico State University), Shivam Chawla

Clear Cell Renal Cell Carcinoma (ccRCC)Transcriptomics Metabolic Pathway Analysis Immunometabolism Gene Set Enrichment Analysis (GSEA)Principal Component Analysis (PCA)

Pathway-Level Insights into Metabolic Reprogramming for Paired Tumor–Normal Proteomics in Head and Neck Cancer

1:15 PM - 2:45 PM

Co-authors: Mawutor Kwasi Agbenor-Efunam, Soyoung Jeon (New Mexico State University), Mawutor Kwasi Agbenor-Efunam

Cancer Metabolism Head and Neck Squamous Cell Carcinoma (HNSCC)Metabolic Pathway Analysis Proteomics Gene Set Enrichment Analysis (GSEA)Principal Component Analysis (PCA)

Single-cell RNA editing defines clinically relevant cellular states in chronic myelomonocytic leukemia

1:15 PM - 2:45 PM

Co-authors: Nisansala Wickramasinghe (Versiti Blood Research Institute), Nisansala Wickramasinghe (Versiti Blood Research Institute), Tongjun Gu (Versiti Blood Research Institute), Doan Bui (Versiti Blood Research Institute), Surendra Neupane (Moffitt Cancer Center), Meghan Ferrall-Fairbanks (University of Florida), Michael Deininger (University of Michigan), Eric Padron (Moffitt Cancer Center)

single cell RNA sequencing RNA editing chronic myelomonocytic leukemia clustering Cellular states

TrialSimulator: Streamlining Simulation for Complex Clinical Trial Designs

1:15 PM - 2:45 PM

Co-authors: Han Zhang (Astellas), Han Zhang (Astellas)

Clinical trial simulation Adaptive designs Multi-arm multi-endpoint design Transparency, reproducibility and auditability Modular software architecture Declarative programming

CS025 Lightning Session 5, Part 1

About this session

14 Presentations