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Project Data Sphere Data Integration Initiatives
Steven B. Cohen
RTI International
Jennifer Unangst
RTI International
The quality and content of national population-based surveys are enhanced through integrated designs that link additional medical, behavioral, environmental, socio-economic and financial content from multiple sectors. In this study, the content in selected Project Data Sphere LLC (PDS) cancer patient-level phase III clinical datasets have been augmented by linking the social, economic, and health-related characteristics of like cancer survivors from nationally representative health and health care-related data from the Medical Expenditure Panel Survey (MEPS). Study findings include probabilistic assessments of the representation of the patients in the respective clinical trials relative to the characteristics of cancer survivors in the general population. The study illustrates the enhancements achieved to the analytic capacity and utility of the PDS cancer clinical trial data through data integration.