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Amy B. Lock

USDA



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Christopher Tong

USDA



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372 – Contributed Oral Poster Presentations: Biopharmaceutical Section

A Computational Procedure for Mean Kinetic Temperature Using Unequally Spaced Data

Sponsor: Biopharmaceutical Section
Keywords: Mean kinetic temperature, stability, Arrhenius equation, Trapezoidal rule

Amy B. Lock

USDA

Christopher Tong

USDA

The mean kinetic temperature (MKT) concept is reviewed and derived from the Arrhenius equation for the case of unequally spaced data. A new computational formula is presented for MKT using timepoint-temperature data pairs at unequally spaced time points, using a trapezoidal approximation. This formula allows the calculation of MKT for data loggers that change their sampling frequency in response to a temperature excursion or other alarm.

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