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Topic-Contributed Paper Session

To See the Unseen: Advancing Drug Development through the Lens of Causal Inference

Mon, Aug 3, 2:00 PM - 3:50 PM Room CC-204B Thomas M. Menino Convention & Exhibition Center

Tianmeng LyuOrganizerDong XiOrganizerDong XiChair

Biopharmaceutical Section co: International Chinese Statistical Associationco: ENAR Applied

5 Presentations

Beyond the map: reflections on causal discovery in drug development

2:05 PM - 2:25 PM

Co-authors: Jack Kuipers (D-BSSE ETH Zurich)

Causal inference Causal discovery

Causal Inference in Indirect Treatment Comparison

2:25 PM - 2:45 PM

Yixin Fang (AbbVie)

Estimand Health Technology Assessment Matching Adjusted Indirect Comparison Targeted Learning

Causal Inference with Missing Covariates: A Unified Bayesian Perspective

2:45 PM - 3:05 PM

Arman Oganisian (Brown University)

missing data causal inference bayesian statistics electronic health records

Mechanisms, Mediators, and Surrogates: Exploring the Role of Mediation Analysis in Clinical Trials

3:05 PM - 3:25 PM

Tianmeng Lyu (Novartis)

Co-authors: Simon Newsome (Novartis)

Mediation Analysis Surrogacy Clinical Trials Drug Development Causal Inference

Separating Signal from Adherence: Causal Decomposition for Bridging Phase 2 and Phase 3 Estimands

3:25 PM - 3:45 PM

Zhili Qiao (Eli Lilly and Company)

Estimands Treatment Adherence Causal decomposition

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