JSM2024
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Contributed Papers

Recent Methodological Advances in Cancer Genomics and Disease Subtyping

Wed, Aug 7, 2:00 PM - 3:50 PM
Hui LiChair
Section on Statistics in Genomics and Genetics

7 Presentations

A novel approach for identifying genetic associations with heterogeneous cancer subtypes risk
2:05 PM - 2:20 PM
Haoyu Zhang (National Cancer Institute)
Co-authors: Diptavo Dutta, Sheng Fu (National Cancer Institute), Xihao Li, Thomas Ahearn (National Cancer Institute), Zilin Li (Northeast Normal University), Kevin Wang (National Cancer Institute), Jin Jin (Johns Hopkins University), Xin Li (National Cancer Institute), Kyriaki Michailidou (Biostatistics Unit, The Cyprus Institute of Neurology & Genetics, Nicosia, Cyprus), Roger Milne (Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia), Peter Kraft (Harvard School of Public Health), Jacques Simard (Genomics Center, Centre Hospitalier Universitaire de Québec), Paul Pharoah (University of Cambridge), Marjanka Schmidt (The Netherlands Cancer Institute), Douglas Easton (University of Cambridge), Nilanjan Chatterjee, Montserrat Garcia-Closas (The Institute of Cancer Research), Yu Kai (National Cancer Institute)
A Semi-Parametric Approach for Longitudinal Outcome-Guided Disease Subtyping Using High-Dimensional Omics Data
2:20 PM - 2:35 PM
Boyi Hu
Co-authors: Yuanjia Wang (Columbia University), Annie Lee (Columbia University Irving Medical Center)
Adaptation of a mutual exclusivity framework to identify driver mutations within oncogenic pathways
2:35 PM - 2:50 PM
Xinjun Wang (Memorial Sloan Kettering Cancer Center)
Co-authors: Caroline Kostrzewa (Memorial Sloan Kettering Cancer Center), Allison Reiner (Memorial Sloan Kettering Cancer Center), Ronglai Shen (Memorial Sloan-Kettering Cancer Center), Colin Begg (Memorial Sloan-Kettering Cancer Center)
Bayesian selection and refitting of reference mutational signatures in cancer genomics
2:50 PM - 3:05 PM
Min Hua (NCI/NIH)
Co-authors: Bin Zhu (NCI/NIH)
Enhancing radiogenomic analysis in breast cancer using a generative neural network approach
3:05 PM - 3:20 PM
Pingzhao Hu
Nonnegative Matrix Factorization with Patient Survival to Find Clinically-relevant Gene Signatures
3:20 PM - 3:35 PM
Amber Marie Young
Co-authors: Alisa Yurovsky (Stony Brook University), Richard Moffitt (Emory University), Didong Li, Naim Rashid (UNC Chapel Hill)
Pathway-guided Bayesian framework identifies cancer subgroups by integrating mulitple genomic data
3:35 PM - 3:50 PM
Zequn Sun (Northwestern University)
Co-authors: Dongjun Chung (The Ohio State University), Brian Neelon (Medical University of South Carolina)
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