Bayesian Methods and Applications in Clinical Trials

Sun, Aug 4, 2:00 PM - 3:50 PM

Jingyi LinChair

Biopharmaceutical Section

6 Presentations

A generalized Bayesian hierarchical model in basket trials

2:05 PM - 2:20 PM

Ruoxuan Xiang (U.S. FDA)

A robust empirical balancing prior for information integration in platform trials

2:20 PM - 2:35 PM

Evan Kwiatkowski (University of Texas Health Science Center at Houston)

Co-authors: Ying Yuan (University of Texas, MD Anderson Cancer Center), Jing Ning (University of Texas, MD Anderson Cancer Center), Maomao Ding (Rice University), Ruitao Lin (University of Texas, MD Anderson Cancer Center)

Benefits of Bayesian Priors as Regularizers in Challenging Meta-analysis Settings

2:35 PM - 2:50 PM

Emma Mackay (Inka Health)

Comparison of three dynamic borrowing approaches to augment time-to-event endpoint in RCTs

2:50 PM - 3:05 PM

Kexin Jin (Bristol Myers Squibb)

Co-authors: Zhi Yang (BMS), Min Chen (Bristol Myers Squibb), Ram Tiwari (Bristol Myers Squibb), Jerry Li (BMS)

Short-term endpoints as surrogates in Bayesian phase II trials with dose selection

3:05 PM - 3:20 PM

Marcio Diniz (Icahn School of Medicine)

Co-authors: Mourad Tighiouart (Cedars-Sinai Medical Center)

Unblinded by the Night: Conditional Power for Complex Bayesian Adaptive Trials when Sight Privileges

3:20 PM - 3:35 PM

Byron Gajewski (University of Kansas Medical Center)

Co-authors: Renee Martin (Medical University of South Carolina), Jonathan Beall (Medical University of South Carolina), Scott Berry (Berry Consultants)