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Topic-Contributed Paper Session

The Analysis of GFR Slope and other Biomarkers in Longitudinal Studies of Chronic Kidney Disease

Wed, Aug 7, 8:30 AM - 10:20 AM

Vivek CharuOrganizerMaria Montez-RathChair

Section on Statistics in Epidemiology

5 Presentations

Shared Parameter Models for GFR Slope in Clinical Trials for Chronic Kidney Disease with Competing Dropout Mechanisms

8:35 AM - 8:55 AM

Edward Vonesh (Vonesh Statistical Consulting, LLC)

Applying the Trial-Level Surrogate Endpoint Framework to Evaluate Alternative GFR Slope Outcomes for Clinical Trials in Chronic Kidney Disease

8:55 AM - 9:15 AM

Willem Collier (University of Utah)

Relaxing Linearity Assumptions for GFR Slope Analysis in Clinical Trials of Chronic Kidney Disease

9:15 AM - 9:35 AM

Tom Greene (University of Utah)

Backward joint models of multivariate longitudinal biomarker trajectories and clinical event endpoints, with application to renal research

9:35 AM - 9:55 AM

Liang Li (University of Texas MD Anderson Cancer Center)

Characterizing heterogeneous treatment effects on GFR slope in clinical trials for chronic kidney disease

9:55 AM - 10:15 AM

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