JSM2024
Back to the program
Invited Paper Session

Adaptive Enrichment Designs: Pitfalls and Promises for Targeted Therapies

Thu, Aug 8, 10:30 AM - 12:20 PM
Ruixiao LuChairErik BloomquistOrganizer
Biopharmaceutical Section

4 Presentations

A Promising Biomarker Adaptive Phase 2/3 design – Explained and Expanded
10:35 AM - 10:55 AM
Cong Chen (Merck & Co., Inc.)
Adaptive Enrichment Designs with Information Monitoring and Covariate Adjustment
10:55 AM - 11:15 AM
Michael Rosenblum (Johns Hopkins University, Bloomberg School of Public Health)
Co-authors: Kelly Van Lancker (Ghent University)
An Adaptive Seamless 2-in-1 Design with Biomarker-Driven Subgroup Enrichment
11:15 AM - 11:35 AM
Liwen Wu (Takeda Pharmaceuticals)
Co-authors: Jianchang Lin (Takeda)
Two-Stage Enrichment Designs With a Continuous Biomarker
11:35 AM - 11:55 AM
William Rosenberger (George Mason University)
Co-authors: Nancy Flournoy, Zhantao Lin (George Mason University)

Discussant

Sunhee Ro (Prelude Therapeutics)
↑