Contributed Papers

Subgroup Applications in Clinical Trials

Wed, Aug 9, 8:30 AM

Junshui MaChair

Biopharmaceutical Section

7 Presentations

WITHDRAWN IBIS: Identify Biomarker-Based Subgroups with a Bayesian Enrichment Design for Targeted Combination

8:35 AM - 8:50 AM

Co-authors: Fangrong Yan, Xin Chen (Department of Biostatistics, China Pharmaceutical University), Jingyi Zhang (Department of Biostatistics, China Pharmaceutical University), Liyun Jiang (Department of Biostatistics, China Pharmaceutical University)

Impact Assessment of Systematic Mis-Stratification Issue on Trials with Dual Primary Endpoints

8:50 AM - 9:05 AM

Kaushal Mishra

Co-authors: Jacy Sparks, Archie Sachdeva, Liping Huang (Bristol Myers Squibb), Ram Tiwari (Bristol Myers Squibb), Kalyanee Viraswami-Appanna (Bristol Myers Squibb)

Predicting subgroup treatment effects: Organization & learnings from company-internal data challenge

9:05 AM - 9:20 AM

Ruvie Martin (Novartis Pharmaceuticals)

Statistical considerations of central reading in clinical trials

9:20 AM - 9:35 AM

Zijiang Yang

Co-authors: Ahmad Hakeem Abdul Wahab (Janssen), Lucy Lu (Janssen R&D)

Subgroup Evaluation Using Bayesian Framework