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CC = Walter E. Washington Convention Center M = Marriott Marquis Washington, DC
* = applied session ! = JSM meeting theme
Activity Details
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30
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Sun, 8/7/2022,
2:00 PM -
3:50 PM
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CC-204C
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Statistical Considerations in Adaptive Designs — Contributed Papers
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Biopharmaceutical Section
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Chair(s): Meijing Wu, Sanofi
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2:05 PM
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Bayesian Empirical Balancing Calibration for Addressing Nonconcurrent Controls in Adaptive Platform Trials
Evan Kwiatkowski, Rice University; Ying Yuan , the University of Texas MD Anderson Cancer Center; Ruitao Lin, MD Anderson
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2:20 PM
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Response-Adaptive Randomization for Precision Medicine Trials and the Pure-Exploration Contextual Bandit Problem
John Sperger, University of North Carolina at Chapel Hill; Michael Kosorok, University of North Carolina at Chapel Hill
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2:35 PM
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Optimal Adaptive Promising Zone Designs
Lingyun Liu, Vertex Pharmaceuticals; Cyrus Mehta, Cytel; Apurva Bhingare, Bristol Myers Squibb; Pralay Senchaudhuri, Cytel Corporation
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2:50 PM
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Generalized Conditional Power for Correlated Continuous Co-Primary Endpoints
Zejiang Yang, Syneos Health
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3:05 PM
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A Note on Multiplicity Control for Trials with Adaptation Based on Intermediate Endpoint
Wenjun Zheng, Regeneron Pharmaceuticals; Chenguang Wang, Regeneron Pharmaceuticals; Bret Musser, Regeneron Pharmaceuticals
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3:20 PM
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Overall Type I Error Control for Seamless 2/3 Adaptive Design Using Biomarkers
Xin Wang, Bristol Myers Squibb; Rong Fan, Bristol Myers Squibb
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3:35 PM
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Adaptive Two-Stage Design with Count Data
Yaohua Zhang, Vertex Pharmaceuticals; Bingming Yi , Vertex Pharmaceuticals; Lingyun Liu, Vertex Pharmaceuticals; Indrias Berhane, Vertex Pharmaceuticals
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