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CC = Walter E. Washington Convention Center   M = Marriott Marquis Washington, DC
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Activity Details

323 * ! Tue, 8/9/2022, 2:00 PM - 3:50 PM CC-201
Adaptive Enrichment Designs in Clinical Trials — Topic Contributed Papers
Biopharmaceutical Section, Biometrics Section, ENAR
Organizer(s): Daniel Zhao, University of Oklahoma
Chair(s): Daniel Zhao, University of Oklahoma
2:05 PM Adaptive Designs with Modified Testing Hierarchy at the Interim
George Kordzakhia, Astra Zeneca; Cassie Dong, Takeda ; Eiji Ishida, Sunovion
2:25 PM A Bayesian Group Sequential Enrichment Design with Adaptive Regression of Response and Survival Time on Baseline Biomarkers
Peter Thall, The University of Texas MD Anderson Cancer Center; Yeonhee Park, University of Wisconsin-Madison; Suyu Liu, The University of Texas MD Anderson Cancer Center; Ying Yuan , the University of Texas MD Anderson Cancer Center
2:45 PM Overview of Existing Methods for Biomarker-Driven Adaptive Designs
Ilya Lipkovich, Eli Lilly and Company; Sarah Johnston, Bristol-Myers Squibb; Alex Dmitrienko, Mediana, Inc; Daniel Zhao, University of Oklahoma
3:05 PM Decision Theoretic Approaches for the Design of Adaptive Enrichment and Umbrella Trials
Martin Posch, Medical University of Vienna
3:25 PM Discussant: Brian Wiens, ACELYRIN, INC.
3:45 PM Floor Discussion