All Times EDT
Legend: CC = Walter E. Washington Convention Center M = Marriott Marquis Washington, DC
Activity Details
135 * !
Mon, 8/8/2022,
10:30 AM -
12:20 PM
CC-203AB
The Use of Baseline Covariates and Early Read-Outs in Adaptive and Group Sequential Designs: Worth the Effort? — Topic Contributed Papers
Biopharmaceutical Section
Organizer(s): Lisa Hampson, Novartis Pharma AG, Switzerland; Kelly Van Lancker, Johns Hopkins University, Bloomberg School of Public Health, US and Ghent University, Belgium
Chair(s): Lisa Hampson, Novartis Pharma AG, Switzerland
10:35 AM
Combining Covariate Adjustment with Group Sequential and Information Adaptive Designs to Improve Randomized Trial Efficiency
Michael Rosenblum, Johns Hopkins Bloomberg School of Public Health
10:55 AM
Using a Combination of Early and Primary Endpoint Data in Group-Sequential and Interrupted Clinical Trials
Nigel Stallard, University of Warwick
11:15 AM
Use of Short-Term Outcomes in Adaptive Seamless Designs with Treatment or Subgroup Selection
Tim Friede, University Medical Center Goettingen
11:35 AM
MIRROS: Planning a Phase 3 Trial with Time-to-Event Endpoint, a Cure Proportion, and a Futility Interim Analysis Using Response
Kaspar Rufibach, F. Hoffmann-La Roche ; Dominik Heinzmann, F. Hoffmann-La Roche; Annabelle Monnet, F. Hoffmann-La Roche
11:55 AM
Joint Modeling of Longitudinal and Time-to-Event Data Applied to Adaptive Clinical Trials
Abigail Burdon, University of Cambridge
12:15 PM
Floor Discussion
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