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Activity Number:
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386
- SPEED: Statistics in Epidemiology Part 1
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Type:
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Contributed
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Date/Time:
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Wednesday, August 10, 2022 : 8:30 AM to 10:20 AM
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Sponsor:
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Section on Statistics in Epidemiology
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Abstract #322372
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Title:
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Cancer Incidence, Latency, and Survival in World Trade Center Rescue/Recovery Workers
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Author(s):
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Charles B Hall* and Andrew Christian Todd and James E Cone and Jiehui Li and David G Goldfarb and Rachel Anna Zeig-Owens and Paolo Boffetta
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Companies:
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Albert Einstein College of Medicine and Icahn School of Medicine at Mount and New York City Department of Health and Mental Hygiene, World Trade Center Health Registry and New York City Department of Health and Mental Hygiene, World Trade Center Health Registry and Montefiore Medical Center, Fire Department of the City of New York, City University of NY and Montefiore Medical Center and Stony Brook Cancer Center
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Keywords:
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Cancer;
Incidence;
Latency;
Survival;
Change Points
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Abstract:
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The terrorist attack and building collapse at the World Trade Center (WTC) in New York City on 9/11/2001 resulted in tens of thousands of rescue/recovery workers (RRWs) being exposed to a wide variety of carcinogens. We pooled data from three cohorts of World Trade Center rescue/recovery workers – the Fire Department of the City of New York, the General Responder Cohort, and the World Trade Center Health Registry. The New York State Cancer Registry performed the pooling, accounting for individuals who are in more than one cohort, and linked to 12 additional state cancer registries. We largely confirmed elevated incidence of cancer from some sites previously identified in analyses of individual cohort analyses as being sites of concern, identified one additional site with elevated incidence, identified some sites with lower-than-expected incidence, and found a shorter than expected latency period for two sites. Our most notable finding was a surprisingly strong survival benefit for WTC RRWs enrolled in a NIOSH-sponsored WTC Health Program medical monitoring program. In this talk we will discuss methodological challenges encountered in this research, and future directions.
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Authors who are presenting talks have a * after their name.
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