|
Activity Number:
|
412
- Emerging Challenges and Novel Methods for Treatment Benefit Evaluation
|
|
Type:
|
Topic Contributed
|
|
Date/Time:
|
Wednesday, August 10, 2022 : 10:30 AM to 12:20 PM
|
|
Sponsor:
|
Section on Statistical Consulting
|
|
Abstract #322093
|
|
|
Title:
|
Functional ANOVA on Biorhythm-Adjusted Physical Activity via Curve Registration Using Wearable Device Measured Data
|
|
Author(s):
|
Yei Eun Shin*
|
|
Companies:
|
National Cancer Institute
|
|
Keywords:
|
FANOVA;
curve registration;
circadian rhythm analysis ;
wearable device;
physical activity
|
|
Abstract:
|
Understanding how the improvement of physical activity in daily life can reduce disease risk is an important area in public health. The use of wearable devices provides researchers the opportunity to explore the relationship between complex features of circadian rhythm on disease risk in a more precise and systematic fashion. This talk presents functional ANOVA to compare variabilities of physical activity curves between groups or evaluate treatment effects on physical activity. The potential confounding effect of varying biorhythm within an individual or between individuals, such as different onset times of wake or sleep, will be adjusted by using curve registration techniques. This feature-aligned approach enables the exploration of the variability of physical activity curves in a more selective and informative way. The developed method will be illustrated with an application to NHANES data.
|
Authors who are presenting talks have a * after their name.
