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Activity Number: 375 - Causal Estimand in Clinical Trials
Type: Topic Contributed
Date/Time: Wednesday, August 10, 2022 : 8:30 AM to 10:20 AM
Sponsor: Biometrics Section
Abstract #320834
Title: Covariate Adjustment and Missing Data in Clinical Trials
Author(s): Daniel Rubin*
Companies: U.S. Food and Drug Administration
Keywords:
Abstract:

While the main goal of adjusting for baseline covariates in randomized clinical trials is often to improve the precision of treatment effect estimation, adjusted methods can also have advantages relative to unadjusted methods in terms of accounting for missing data. This presentation will discuss several recommendations for implementing covariate adjustment in the presence of missing covariates or outcomes.


Authors who are presenting talks have a * after their name.

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