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Activity Number: 120 - Recent Developments in Causal Inference
Type: Invited
Date/Time: Monday, August 8, 2022 : 10:30 AM to 12:20 PM
Sponsor: IMS
Abstract #319212
Title: Energy Balancing of Covariate Distributions for Estimation of Causal Effects
Author(s): Jared Davis Huling* and Simon Mak
Companies: University of Minnesota and Duke University
Keywords: Causal Inference; Covariate balance; energy distance; Confounding; Observational data
Abstract:

Bias in causal comparisons has a direct correspondence with distributional imbalance of covariates between treatment groups. Weighting strategies such as inverse propensity score weighting attempt to mitigate bias by either modeling the treatment assignment mechanism or balancing specified covariate moments. This paper introduces a new weighting method, called energy balancing, which instead aims to balance weighted covariate distributions. By directly targeting distributional imbalance, the proposed weighting strategy can be flexibly utilized in a wide variety of causal analyses, including the estimation of average treatment effects and individualized treatment rules. Our energy balancing weights (EBW) approach has several advantages over existing weighting techniques. It offers a model-free and robust approach for obtaining covariate balance that does not require tuning parameters, obviating the need for modeling decisions of secondary nature to the scientific question at hand. We demonstrate the effectiveness of this EBW approach in a suite of simulation experiments, and in studies using electronic health record data.


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