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Activity Number: 401 - Real-World Survival Data with Multiple Events: Challenges, Opportunities, and Recent Advancements
Type: Invited
Date/Time: Wednesday, August 10, 2022 : 10:30 AM to 12:20 PM
Sponsor: Lifetime Data Science Section
Abstract #319198
Title: Dependent Censoring Based on Copulas
Author(s): Ingrid Van Keilegom* and Claudia Czado
Companies: KU Leuven and Technical University of Munich
Keywords: Copulas; Dependent censoring; Identifiability; Inference
Abstract:

Consider a survival time T that is subject to random right censoring, and suppose that T is stochastically dependent on the censoring time C. We are interested in the marginal distribution of T. In this paper we propose a new model that takes this dependence into account. The model is based on a parametric copula for the relationship between T and C, and on parametric marginal distributions for T and C. Unlike most other papers in the literature, we do not assume that the parameter defining the copula function is known. We give sufficient conditions on these parametric copula and marginals under which the bivariate distribution of (T,C) is identified. These sufficient conditions are then checked for a wide range of common copulas and marginal distributions. We also study the estimation of the model, and carry out extensive simulations and the analysis of data on pancreas cancer to illustrate the proposed model and estimation procedure.


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