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Activity Details

195 Tue, 8/4/2020, 10:00 AM - 2:00 PM Virtual
Topics in Personalized/Precision Medicine - II — Contributed Papers
Biopharmaceutical Section
Chair(s): Jennifer Bogert, Janssen / Johnson & Johnson
From Illogical Efficacy Measures to Mistakes in Current Computer Packages – All That Is Wrong in Biomarker Subgroup Identification with Real Example and Proposed Solution
Jason Hsu, Ohio State University; Yi Liu, Nektar Therapeutics; Bushi Wang, Boehringer Ingelheim Pharmaceuticals, Inc.
One-Step Value Difference Test for the Existence of a Subgroup with a Beneficial Treatment Effect Using Random Forests
Dana Johnson, North Carolina State University; Wenbin Lu , North Carolina State University; Marie Davidian, North Carolina State University
Boosting Algorithms for Estimating Optimal Individualized Treatment Rules
Duzhe Wang, University of Wisconsin-Madison; Haoda Fu, Eli Lilly and Company; Po-Ling Loh, UW-Madison
Inference on Selected Subgroups in Clinical Trials
Xinzhou Guo, Harvard University; Xuming He, University of Michigan
A Benchmark Framework for Subgroup Identification Methods in Clinical Trials
Hui Sun, Novartis Parmaceuticals; Ardalan Mirshani, Novartis; Bjoern Bornkamp, Novartis
Matching-Based Classification Tree for Subgroup Effect Identification in Observational Data
Bo Lu, The Ohio State University
Three mistakes in current stratified analyses and confident patient subgroup identification for randomized controlled trials, using a Subgroup Mixable Estimation app
Siyoen Kil, LSK Global PS; Jason Hsu, Ohio State University