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195
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Tue, 8/4/2020,
10:00 AM -
2:00 PM
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Virtual
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Topics in Personalized/Precision Medicine - II — Contributed Papers
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Biopharmaceutical Section
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Chair(s): Jennifer Bogert, Janssen / Johnson & Johnson
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From Illogical Efficacy Measures to Mistakes in Current Computer Packages – All That Is Wrong in Biomarker Subgroup Identification with Real Example and Proposed Solution
Jason Hsu, Ohio State University; Yi Liu, Nektar Therapeutics; Bushi Wang, Boehringer Ingelheim Pharmaceuticals, Inc.
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One-Step Value Difference Test for the Existence of a Subgroup with a Beneficial Treatment Effect Using Random Forests
Dana Johnson, North Carolina State University; Wenbin Lu , North Carolina State University; Marie Davidian, North Carolina State University
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Boosting Algorithms for Estimating Optimal Individualized Treatment Rules
Duzhe Wang, University of Wisconsin-Madison; Haoda Fu, Eli Lilly and Company; Po-Ling Loh, UW-Madison
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Inference on Selected Subgroups in Clinical Trials
Xinzhou Guo, Harvard University; Xuming He, University of Michigan
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A Benchmark Framework for Subgroup Identification Methods in Clinical Trials
Hui Sun, Novartis Parmaceuticals; Ardalan Mirshani, Novartis; Bjoern Bornkamp, Novartis
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Matching-Based Classification Tree for Subgroup Effect Identification in Observational Data
Bo Lu, The Ohio State University
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Three mistakes in current stratified analyses and confident patient subgroup identification for randomized controlled trials, using a Subgroup Mixable Estimation app
Siyoen Kil, LSK Global PS; Jason Hsu, Ohio State University
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