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488 * Thu, 8/6/2020, 10:00 AM - 2:00 PM Virtual
Estimands and Imputation Methods — Contributed Papers
Biopharmaceutical Section
Chair(s): Nabanita Mukherjee, AbbVie
Monotonicity Assumption in the Estimation of Treatment Effect for a Principal Stratum
Yongming Qu, Eli Lilly and Company; Ilya Lipkovich, Eli LIlly and Company; Steve Ruberg, Analytix Thinking, LLC
Statistical Analysis Approach for Principle Stratum Estimand
David Li, Eisai
Estimating Causal Effects for Adherers in a Randomized Trial Using Multiple Imputation
Junxiang Luo, Sanofi; Yongming Qu, Eli Lilly and Company; Steve Ruberg, Analytix Thinking, LLC
Missing Data Analysis for Recurrent Events
Madhurima Majumder, Bayer US LLC; Yuan Hong, University of South Carolina-Columbia; Arno Fritsch, Bayer AG
Tipping Point Analysis for Time-to-Event Endpoints in Oncology Clinical Trials
Arunava Chakravartty, Novartis Pharmaceuticals
Multiple Imputation for the Estimation of Treatment and Biomarker Interaction Effect in Oncology Phase III Clinical Trials
Feng Liu, Astrazeneca; Binbing Yu, Astrazeneca; Helen Mann, AstraZeneca