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62 Mon, 8/3/2020, 10:00 AM - 2:00 PM Virtual
Topics in Adaptive Designs: Adaptive-Seamless, Group Sequential and Other Designs — Contributed Papers
Biopharmaceutical Section
Chair(s): Cristiana Mayer, Janssen / Johnson & Johnson
Seamless Adaptive Phase 2-3 Designs Allowing for Mid-Term Modifications Using Multiplicity Strategy
Mandy Jin, AbbVie Inc.
Overview of Recent Advances in Biomarker Driven Adaptive Designs
Ilya Lipkovich, Eli LIlly and Company; Sarah E Johnson , University of Oklahoma Health Sciences Center; Alex Dmitrienko , Mediana, Inc; Daniel Zhao , University of Oklahoma Health Sciences Center
Adaptive Simon’s Two-Stage Design with or Without Targeting Biomarker Subpopulation
Weichao Bao, Bayer
An Adaptive-Flavored Group Sequential Design with Connection to Conditional Error
Dong Xi, Novartis; Paul Gallo, Novartis
Automated Design of Adaptive Trials Using Bayesian Optimization
Joe Marion, Berry Consultants
Early Phase Cancer Clinical Trial Design for Dose Finding of Treatment Combinations Across Patient Groups
Bethany Horton, University of Virginia