Online Program Home
  My Program

All Times EDT

Abstract Details

Activity Number: 120 - Recent Advances in Vaccine Dose and Regimen Finding
Type: Topic Contributed
Date/Time: Monday, August 3, 2020 : 1:00 PM to 2:50 PM
Sponsor: Biopharmaceutical Section
Abstract #312318
Title: Considerations in Vaccine Dose-Finding Studies
Author(s): Aiying Chen* and Scott Patterson and Fabrice Bailleux and Tifany Machabert
Companies: sanofi Pasteur and Sanofi Pasteur and Sanofi Pasteur and Sanofi Pasteur
Keywords: vaccine dose-finding; Bayesian method; Safety

Vaccine dose-finding studies evaluate the safety and immunogenicity of doses of a new vaccine in healthy adult volunteers, subject to manufacturing and clinical safety constraints. Safety of subjects is the paramount concern, and in some circumstances, Bayesian methods may be applied to monitor ongoing data. An example will be provided to illustrate

Authors who are presenting talks have a * after their name.

Back to the full JSM 2020 program