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Activity Number:
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120
- Recent Advances in Vaccine Dose and Regimen Finding
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Type:
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Topic Contributed
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Date/Time:
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Monday, August 3, 2020 : 1:00 PM to 2:50 PM
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Sponsor:
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Biopharmaceutical Section
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Abstract #312318
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Title:
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Considerations in Vaccine Dose-Finding Studies
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Author(s):
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Aiying Chen* and Scott Patterson and Fabrice Bailleux and Tifany Machabert
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Companies:
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sanofi Pasteur and Sanofi Pasteur and Sanofi Pasteur and Sanofi Pasteur
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Keywords:
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vaccine dose-finding;
Bayesian method;
Safety
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Abstract:
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Vaccine dose-finding studies evaluate the safety and immunogenicity of doses of a new vaccine in healthy adult volunteers, subject to manufacturing and clinical safety constraints. Safety of subjects is the paramount concern, and in some circumstances, Bayesian methods may be applied to monitor ongoing data. An example will be provided to illustrate
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Authors who are presenting talks have a * after their name.
