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Abstract:
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We compare the topological features of functional brain networks. In general, functional brain networks are dealt with in an elementwise manner based on the connectivity matrix as part of network data analysis. This tends to ignore the higher-order topology of the network, which can have significant implications. In recent studies, researchers have been interested in topological data analysis. Persistent homology is known to be useful for studying dynamic topological invariants hidden in complex data obtained from topological space. Analysis using persistent homology not only captures topological features that could be overlooked in the network data analysis but also addresses threshold selection problems commonly found in network data analysis. We use persistent homology to compare the topological features of brain networks. We construct a brain network from the fMRI time series BOLD signal and calculate the persistent homology through the weighted brain network. Also, we compare the summarized topological features of different subject groups by calculating the persistence landscape.
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