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CC = Colorado Convention Center   H = Hyatt Regency Denver at Colorado Convention Center
* = applied session       ! = JSM meeting theme

Activity Details

CE_26C Tue, 7/30/2019, 1:00 PM - 5:00 PM CC-406
Adaptive Treatment Strategies: An Introduction to Statistical Approaches for Estimation (ADDED FEE) — Professional Development Continuing Education Course
ASA, Biometrics Section
Evidence-based medicine relies on using data to provide recommendations for effective treatment decisions. However, in many settings, response is heterogeneous across patients. Patient response may also vary over time, and physicians are faced with the daunting task of making sequential therapeutic decisions having seen few patients with a given clinical history. Adaptive treatment strategies (ATS) operationalize the sequential decision-making process in the precision medicine paradigm, offering statisticians principled estimation tools that can be used to incorporate patient’s characteristics into a clinical decision-making framework so as to adapt the type, dosage or timing of treatment according to patients’ evolving needs. This half-day course will provide an overview of precision medicine from the statistical perspective. We will begin with a discussion of relevant data sources. We will then turn our attention to estimation, and consider multiple approaches – and their relative strengths and weaknesses – to estimating tailored treatment rules in a one-stage setting. Next, we will consider the multi-stage setting and inferential challenges in this area. Relevant clinical examples will be discussed, as well available software tools.
Instructor(s): Erica Moodie, McGill university