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Activity Number: 362 - SPEED: Food, Environment, Biomedical Imaging and Physical System Visualization/Learning, Part 2
Type: Contributed
Date/Time: Tuesday, July 30, 2019 : 11:35 AM to 12:20 PM
Sponsor: Section on Statistics in Imaging
Abstract #307795
Title: Analytic White Matter Tractography and Compositional Distance Based Summarization of White Matter Brain Structures
Author(s): Wendy Meiring* and Matthew Cieslak and Tegan Brennan and Subhash Suri and Scott T. Grafton
Companies: University of California At Santa Barbara and U.Penn and UCSB and UCSB and UCSB
Keywords: Diffusion MRI; White matter connectivity; Analytic tractography; Compositional Data Analysis

We present an analytic (simulation free) method for calculating white matter transition probabilities between neighboring brain voxels based on DSI structural MRI, including phantom evaluation, human invivo studies, and Voxel Graph tractography illustrations. We also present two new voxelwise univariate summary measures based on compositional data distances to describe features in white matter, including highlighting complex brain regions with splitting/fanning/kissing fibers. Our new summaries provide valuable additional insights beyond commonly used voxelwise white matter descriptors such as fractional anisotropy (FA).

Authors who are presenting talks have a * after their name.

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