Activity Number:
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237
- SPEED:Statistical Methods for GWAs, Genetics, Genomics, and Other Omics Studies, Part 1
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Type:
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Contributed
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Date/Time:
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Monday, July 29, 2019 : 2:00 PM to 3:50 PM
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Sponsor:
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Section on Statistics in Genomics and Genetics
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Abstract #307095
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Presentation
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Title:
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Trait Evolution on Two Gene Trees
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Author(s):
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James Degnan* and Huan Jiang
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Companies:
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University of New Mexico and Dialysis INC
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Keywords:
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phylogenetics;
evolution;
genetics
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Abstract:
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Models of trait evolution use a phylogenetic tree to determine the correlation structure for traits sampled from a set of species. Typically, the phylogenetic tree estimated from genetic data from many loci, and a single tree is used to model the trait evolution, for example by assuming that the mean trait value follows a Brownian motion on the tree. Here, we model trait evolution by assuming that there are two genetic loci influencing the trait. In this case separate evolutionary trees (called gene trees) can occur for the two loci. We model the correlation structure as arising from a linear combination of Brownian motions on the two trees, and develop a model to estimate the proportion of trait evolution contributed by each gene.
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Authors who are presenting talks have a * after their name.
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