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Activity Number: 240 - Topics in Multiplicity and Control of False Discovery Rate
Type: Contributed
Date/Time: Monday, July 29, 2019 : 2:00 PM to 3:50 PM
Sponsor: Biopharmaceutical Section
Abstract #304849
Title: MULTIPLE TESTING METHODS for A-PRIORI ORDERED HYPOTHESES
Author(s): Anjana Grandhi*
Companies: Merck & Co.
Keywords: FDR; a-priori ordered hypotheses
Abstract:

In multiple testing problems it is often of interest to test a sequence of hypotheses allowing all the hypotheses a chance to be tested. The existing step-wise FDR controlling procedures, such as the Benjamini-Hochberg procedure, are not applicable here because the testing process stops after a certain threshold is reached. In this research, powerful procedures are developed under various dependencies for controlling FDR that allow testing of all hypotheses in a sequence. Simulation studies demonstrate the effectiveness of these procedures in terms of FDR control and average power.


Authors who are presenting talks have a * after their name.

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